ATE289685T1 - Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben - Google Patents

Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben

Info

Publication number
ATE289685T1
ATE289685T1 AT03103218T AT03103218T ATE289685T1 AT E289685 T1 ATE289685 T1 AT E289685T1 AT 03103218 T AT03103218 T AT 03103218T AT 03103218 T AT03103218 T AT 03103218T AT E289685 T1 ATE289685 T1 AT E289685T1
Authority
AT
Austria
Prior art keywords
cervical
solubilized
carcinomas
body sample
overexpression
Prior art date
Application number
AT03103218T
Other languages
English (en)
Inventor
Ruediger Dr Ridder
Anja Dr Reichert
Matthias Dr Herkert
Knebel Doeberitz Magnus Dr Von
Original Assignee
Mtm Lab Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mtm Lab Ag filed Critical Mtm Lab Ag
Application granted granted Critical
Publication of ATE289685T1 publication Critical patent/ATE289685T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57411Specifically defined cancers of cervix
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT03103218T 2003-08-25 2003-08-25 Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben ATE289685T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03103218A EP1507148B1 (de) 2003-08-25 2003-08-25 Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben

Publications (1)

Publication Number Publication Date
ATE289685T1 true ATE289685T1 (de) 2005-03-15

Family

ID=33560881

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03103218T ATE289685T1 (de) 2003-08-25 2003-08-25 Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
AT04104026T ATE461449T1 (de) 2003-08-25 2004-08-20 Verfahren zum nachweis von medizinisch relevanten zuständen in gelösten lbc-proben

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04104026T ATE461449T1 (de) 2003-08-25 2004-08-20 Verfahren zum nachweis von medizinisch relevanten zuständen in gelösten lbc-proben

Country Status (13)

Country Link
US (1) US7932047B2 (de)
EP (2) EP1507148B1 (de)
JP (2) JP5619336B2 (de)
CN (1) CN1836166B (de)
AT (2) ATE289685T1 (de)
AU (1) AU2004317284B2 (de)
BR (1) BRPI0414030B8 (de)
CA (1) CA2528490C (de)
DE (2) DE60300339T2 (de)
ES (1) ES2342535T3 (de)
MX (1) MXPA05013903A (de)
RU (1) RU2405158C2 (de)
WO (2) WO2005088311A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
EP1510820B1 (de) * 2003-08-25 2010-03-17 MTM Laboratories AG Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
CA2652118C (en) * 2006-05-11 2015-07-07 Becton, Dickinson And Company Method of protein extraction from cells
US8859218B2 (en) 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US9207240B2 (en) 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
US10365279B2 (en) 2008-01-25 2019-07-30 Berg Llc Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy
US20090204009A1 (en) * 2008-02-07 2009-08-13 Los Alamos National Security Medical device system and related methods for diagnosing abnormal medical conditions based on in-vivo optical properties of tissue
AU2009289822B2 (en) * 2008-09-04 2015-04-30 Ventana Medical Systems, Inc. Method for prediction of the progression risk of tumors
WO2010062556A1 (en) * 2008-10-27 2010-06-03 Qiagen Gaithersburg Inc. Fast results hybrid capture assay and system
CN101487845B (zh) * 2009-02-19 2013-01-02 苏州海路生物技术有限公司 大便标本自动检测仪
EP2425019B1 (de) 2009-05-01 2014-03-19 QIAGEN Gaithersburg, Inc. Ungezieltes verstärkungsverfahren zur erkennung von rna-spleissformen in einer probe
CN102449479B (zh) * 2009-05-07 2015-11-25 安科健康公司 鉴别高度或≥cin2用于人乳头瘤病毒(hpv)与hpv相关癌症的早期及晚期检测、筛检和诊断
WO2011084598A1 (en) * 2010-01-08 2011-07-14 Oncohealth Corporation High throughput cell-based hpv immunoassays for diagnosis and screening of hpv-associated cancers
US9605303B2 (en) 2010-01-29 2017-03-28 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of an HPV in a sample
AU2011210734B2 (en) 2010-01-29 2017-02-09 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
WO2011146629A2 (en) 2010-05-19 2011-11-24 Qiagen Gaithersburg Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
WO2011158847A1 (ja) 2010-06-17 2011-12-22 国立大学法人 岡山大学 microRNA標的遺伝子検出用キット及びmicroRNA標的遺伝子の検出方法
GB201014335D0 (en) * 2010-08-27 2010-10-13 Forensic Science Service Ltd Improvements in and relating to analysis
SG10201506959SA (en) 2010-09-03 2015-10-29 Stemcentrx Inc Novel modulators and methods of use
CN102033056B (zh) * 2010-10-14 2012-05-30 中国科学院化学研究所 抑制膜蛋白受体聚集的抗癌药物鉴定方法
CA2828224A1 (en) 2011-02-24 2012-08-30 Qiagen Gaithersburg, Inc. Materials and methods for detection of hpv nucleic acids
EP2780714B1 (de) 2011-11-15 2017-08-16 University Of Miami Methoden für den nachweis von humanem papillomavirus und zur prognose von kopf-hals-plattenepithelkarzinom
RU2508542C1 (ru) * 2012-07-16 2014-02-27 Полина Михайловна Шварцбурд Экспресс-способ определения риска злокачественности клеток
RU2535071C1 (ru) * 2013-04-09 2014-12-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия" Министерства здравоохранения Российской Федерации Способ диагностики недифференцированной дисплазии соединительной ткани у женщин с потерей беременности в анамнезе
JP2016527514A (ja) * 2013-07-31 2016-09-08 ユニバーシティー オブ マイアミ 対象の癌リスクを明らかにするための組成物及び方法
WO2015147370A1 (en) * 2014-03-28 2015-10-01 Seegene, Inc. Detection of target nucleic acid sequences using different detection temperatures
RU2558987C1 (ru) * 2014-04-21 2015-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ диагностики степени тяжести недифференцированной дисплазии соединительной ткани у женщин репродуктивного возраста
WO2016198833A2 (en) 2015-06-08 2016-12-15 Arquer Diagnostics Limited Methods
EP4060344A1 (de) 2015-06-08 2022-09-21 Arquer Diagnostics Limited Verfahren und kits
CN106610434A (zh) * 2016-02-26 2017-05-03 弗雷米德生物医药技术(天津)有限公司 一种hpv16型e7蛋白的elisa检测试剂盒
RU2680930C2 (ru) * 2017-03-24 2019-02-28 федеральное государственное бюджетное образовательное учреждение высшего образования "Северный государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ забора материала для цитологического исследования при опухолевых заболеваниях поджелудочной железы, печени и желчевыводящих путей
CN107748265A (zh) * 2017-09-29 2018-03-02 中南大学湘雅医院 Cdc6和ki67在制备癌症放疗抵抗的诊断标记物中的应用
CN111526889B (zh) * 2017-12-29 2023-06-02 沃泰克斯药物股份有限公司 使用atr抑制剂治疗癌症的方法
US11230729B2 (en) * 2018-04-20 2022-01-25 Inanna Diagnostics, Inc Methods and devices for obtaining cellular and DNA material from human female reproductive system
CN109781977B (zh) * 2019-01-09 2022-03-29 首都医科大学附属北京安定医院 IL15Rα以及相关膜蛋白检测试剂盒及其应用
RU2707099C1 (ru) * 2019-04-24 2019-11-22 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации Способ скрининга злокачественных опухолей органов грудной полости
MX380106B (es) * 2019-05-21 2025-03-12 Timser S A P I De C V Biomarcadores relacionados a cancer.
CN117233382A (zh) * 2023-09-08 2023-12-15 江苏默乐生物科技股份有限公司 一种可同时检测低危型和高危型人乳头瘤病毒的抗原检测试剂盒及其应用
CN119639903B (zh) * 2025-01-17 2025-11-25 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 用于肝内胆管癌的生物标记物、药物及其应用

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
EP0584264A1 (de) 1991-05-16 1994-03-02 Cold Spring Harbor Laboratory D-typ cyclin und darauf bezogene anwendungen
US5889169A (en) * 1991-05-16 1999-03-30 Cold Spring Harbor Laboratory Cell cycle regulatory protein p16 gene
DE69229960T2 (de) 1991-12-13 2000-01-05 Bion Diagnostic Sciences, Inc. Agglutierungsassays und kolloide farbstoffe verwendende testsätze
US6316208B1 (en) * 1994-01-07 2001-11-13 Memorial Sloan-Kettering Cancer Center Methods for determining isolated p27 protein levels and uses thereof
CN1128049A (zh) * 1994-03-18 1996-07-31 犹他大学研究基金会 多肿瘤抑制因子基因种系突变及检测该基因癌肿倾向性的方法
US5989815A (en) * 1994-03-18 1999-11-23 University Of Utah Research Foundation Methods for detecting predisposition to cancer at the MTS gene
US6060301A (en) * 1994-03-18 2000-05-09 Myriad Genetics, Inc. Vector containing MTS1E1β gene
CA2164167A1 (en) 1994-12-20 1996-06-21 Izak Bahar Assay normalization method
US6033847A (en) * 1995-02-06 2000-03-07 St. Jude Children's Research Hospital InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof
US5843756A (en) * 1995-06-07 1998-12-01 Myriad Genetics, Inc. Mouse MTSI gene
US6403383B1 (en) * 1996-03-11 2002-06-11 American Bio Medica Corp. Diagnostic test kit for immunological assays of fluid samples
US5976799A (en) * 1996-03-21 1999-11-02 The Board Of Trustees Of The University Of Arkansas Early detection of ovarian carcinoma using P16 gene products
US5955268A (en) * 1996-04-26 1999-09-21 Abbott Laboratories Method and reagent for detecting multiple nucleic acid sequences in a test sample
US5858683A (en) * 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
ATE403744T1 (de) * 1997-05-15 2008-08-15 Univ Jefferson Bestimmung der vorhandenen mengen an cyclin- abhängigem kinase-inhibitor p27 als prognostischem faktor bei krebspatienten
AU8403098A (en) 1997-07-15 1999-02-10 Deaconess Hospital Reagents and methods for diagnosis and prognosis of proliferative disor ders
US6090579A (en) * 1997-08-12 2000-07-18 Smithkline Beecham Corporation Human SDR2 cDNA clone
AU748022B2 (en) * 1997-12-12 2002-05-30 Digene Corporation Universal collection medium
US20010051364A1 (en) * 1997-12-23 2001-12-13 Francis Michon Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines
US7399589B2 (en) * 1998-02-06 2008-07-15 Digene Corporation Immunological detection of RNA:DNA hybrids on microarrays
US5994079A (en) * 1998-02-06 1999-11-30 Digene Corporation Direct detection of RNA mediated by reverse transcriptase lacking RNAse H function
US6686151B1 (en) 1998-02-06 2004-02-03 Digene Corporation Immunological detection of RNA:DNA hybrids on microarrays
US6576420B1 (en) * 1998-06-23 2003-06-10 Regents Of The University Of California Method for early diagnosis of, and determination of prognosis in, cancer
DE19829473C2 (de) * 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
US7306926B2 (en) * 1998-07-01 2007-12-11 Mtm Laboratories Ag Method for detecting carcinomas in a solubilized cervical body sample
US6593084B2 (en) * 1998-10-13 2003-07-15 Robert E. Bird Carcinogen assay
WO2000031538A1 (en) * 1998-11-23 2000-06-02 Praxsys Biosystems, Inc. Improved lateral flow assays
SE515668C2 (sv) * 1999-02-22 2001-09-17 Quantovir Ab Metod och kit för tidig förutsägelse av cancer
DE10014685B4 (de) * 2000-03-24 2004-07-01 Schubert, Walter, Dr. Verfahren zur Identifizierung von zellspezifischen Zielstrukturen
GB0018140D0 (en) 2000-07-24 2000-09-13 Medical Res Council Screening for abnormalities
DE10063179A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
ITRM20010363A1 (it) * 2001-06-25 2001-09-24 Franco Castelmani Gancio adattivo applicato ad un generatore di vivrazioni sinusoidali.
AU2003201639C1 (en) * 2002-01-07 2009-02-26 Norchip A/S Method for detecting human papillomavirus mRNA
EP1333278B1 (de) * 2002-02-01 2004-03-10 MTM molecular tools in medicine Verfahren zur Prognose gastrointestinaler Tumoren
ES2215957T3 (es) * 2002-08-01 2004-10-16 Mtm Laboratories Ag Metodo para diagnostico basado en una solucion.
US7361460B2 (en) * 2003-04-11 2008-04-22 Digene Corporation Approach to molecular diagnosis of human papillomavirus-related diseases

Also Published As

Publication number Publication date
MXPA05013903A (es) 2006-03-09
RU2006101395A (ru) 2006-06-10
EP1507148B1 (de) 2005-02-23
BRPI0414030B1 (pt) 2017-04-04
WO2005088311A1 (en) 2005-09-22
HK1092219A1 (zh) 2007-02-02
BRPI0414030B8 (pt) 2021-07-27
CA2528490A1 (en) 2005-09-22
BRPI0414030A (pt) 2007-01-23
AU2004317284B2 (en) 2009-11-05
CN1836166A (zh) 2006-09-20
ES2342535T3 (es) 2010-07-08
ATE461449T1 (de) 2010-04-15
WO2005084103A2 (en) 2005-09-15
JP5619336B2 (ja) 2014-11-05
CN1836166B (zh) 2010-05-26
RU2405158C2 (ru) 2010-11-27
US20070190529A1 (en) 2007-08-16
CA2528490C (en) 2015-11-03
DE60300339D1 (de) 2005-03-31
US7932047B2 (en) 2011-04-26
JP2012032412A (ja) 2012-02-16
DE602004026014D1 (de) 2010-04-29
EP1664788A1 (de) 2006-06-07
JP5677270B2 (ja) 2015-02-25
DE60300339T2 (de) 2006-04-13
JP2007503208A (ja) 2007-02-22
EP1507148A1 (de) 2005-02-16
AU2004317284A1 (en) 2005-09-22

Similar Documents

Publication Publication Date Title
ATE289685T1 (de) Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
DE59903915D1 (de) Verfahren zur frühen diagnose von carcinomen
MX2007005053A (es) Metodo para evaluar la enfermedad de alzheimer y reactivo de diagnostico.
JOP20200216A1 (ar) تجارب للكشف عن التنكس العصبي
ATE365922T1 (de) Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)
ATE418072T1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
MY145455A (en) Diagnostic biomolecule(s)
KR100711046B1 (ko) 대장암에 대한 마커로서의 니코틴아미드n―메틸트랜스퍼라아제의 용도
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
WO2005124356A3 (en) Use of protein cbp2 as a marker for colorectal cancer
ATE534037T1 (de) Verwendung des proteins asc als marker für brustkrebs
PL1977244T3 (pl) Rozróżnianie bakteryjnego i wirusowego zapalenia opon mózgowych
EP1636587A4 (de) Einen für menschliches protoonkogenes protein spezifischen antikörper enthaltender diagnostischer kit für leberzirrhose
ATE557277T1 (de) Verfahren zur diagnose von endometriose mittels tfpi-2 protein
WO2009016734A1 (ja) 軽度認知機能障害の検定方法
ATA19972000A (de) Pibf für die diagnose von tumoren
EA201001340A1 (ru) Улучшенный аналитический способ для определения латентного гепатита с, его применения и соответствующий диагностический набор
WO2006112962A3 (en) Syphilis diagnostic test and kits
DE602004017017D1 (de) Verwendung des proteins proteasome aktivator untereinheit 3 als marker für kolorektale karzinome
TW200502399A (en) Recombinant virus and use thereof and method of detecting an analyte in a sample and kit thereof
WO2005040807A3 (en) Swiprosin-2 as a breast cancer marker
SG152020A1 (en) Diagnostic methods
WO2003005033A8 (en) Carcinoma-related peptides
WO2005124354A3 (en) Use of protein ch10 as a marker for breast cancer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties