DE4213005B4 - Verwendung von Aromatasehemmern zur Empfängnisverhütung bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus - Google Patents

Verwendung von Aromatasehemmern zur Empfängnisverhütung bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus Download PDF

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Publication number
DE4213005B4
DE4213005B4 DE4213005A DE4213005A DE4213005B4 DE 4213005 B4 DE4213005 B4 DE 4213005B4 DE 4213005 A DE4213005 A DE 4213005A DE 4213005 A DE4213005 A DE 4213005A DE 4213005 B4 DE4213005 B4 DE 4213005B4
Authority
DE
Germany
Prior art keywords
methyl
cyanophenyl
imidazolyl
benzonitrile
triazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE4213005A
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German (de)
English (en)
Other versions
DE4213005A1 (de
Inventor
Ajay Prof. Dr. Bhatnagar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE4213005A1 publication Critical patent/DE4213005A1/de
Application granted granted Critical
Publication of DE4213005B4 publication Critical patent/DE4213005B4/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE4213005A 1991-04-24 1992-04-21 Verwendung von Aromatasehemmern zur Empfängnisverhütung bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus Expired - Fee Related DE4213005B4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1227/91A CH683151A5 (de) 1991-04-24 1991-04-24 Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
CH1227/91 1991-04-24

Publications (2)

Publication Number Publication Date
DE4213005A1 DE4213005A1 (de) 1992-10-29
DE4213005B4 true DE4213005B4 (de) 2005-12-08

Family

ID=4205470

Family Applications (1)

Application Number Title Priority Date Filing Date
DE4213005A Expired - Fee Related DE4213005B4 (de) 1991-04-24 1992-04-21 Verwendung von Aromatasehemmern zur Empfängnisverhütung bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus

Country Status (25)

Country Link
US (1) US5583128A (zh)
JP (1) JP3710830B2 (zh)
KR (1) KR100219017B1 (zh)
AT (1) AT401873B (zh)
AU (1) AU654540B2 (zh)
BE (1) BE1005781A3 (zh)
CA (1) CA2066807C (zh)
CH (1) CH683151A5 (zh)
DE (1) DE4213005B4 (zh)
DK (1) DK176332B1 (zh)
FR (1) FR2675693B1 (zh)
GB (1) GB2256137B (zh)
IE (1) IE64875B1 (zh)
IL (1) IL101688A (zh)
IT (1) IT1257474B (zh)
LU (1) LU88106A1 (zh)
MX (1) MX9201908A (zh)
NL (1) NL9200755A (zh)
NO (1) NO300156B1 (zh)
NZ (1) NZ242443A (zh)
PH (1) PH30495A (zh)
PT (1) PT100409B (zh)
SE (1) SE512618C2 (zh)
TW (1) TW201267B (zh)
ZA (1) ZA922931B (zh)

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ZA9510926B (en) 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6624197B1 (en) 1998-05-08 2003-09-23 Calyx Therapeutics, Inc. Diphenylethylene compounds
US6245814B1 (en) 1998-05-08 2001-06-12 Calyx Therapeutics, Inc. Diphenylethylene compounds
US7105552B2 (en) 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6331633B1 (en) 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6485972B1 (en) 1998-10-15 2002-11-26 President And Fellows Of Harvard College WNT signalling in reproductive organs
US7407978B2 (en) * 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6525093B1 (en) * 1999-11-08 2003-02-25 Calyx Therapeutics Inc. Compounds to treat diabetes and associated conditions
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20020002200A1 (en) * 2000-02-04 2002-01-03 Bishwagit Nag Novel diphenylethylene compounds
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
JP2005515207A (ja) * 2001-12-11 2005-05-26 エモリー ユニバーシティ 乳癌の予防において使用するためのビス（シアノフェニル）メチル−トリアゾール
US8685950B2 (en) * 2004-10-04 2014-04-01 Wayne State University Use of aromatase inhibitors for treatment of ectopic pregnancy
CA2619503A1 (en) * 2005-06-28 2007-01-04 Robert F. Casper Aromatase inhibitors for emergency contraception
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2008019048A1 (en) * 2006-08-04 2008-02-14 Meditrina Pharmaceuticals Use of aromatase inhibitors for thining the endometrium or treating menorrhagia
US20100292150A1 (en) * 2007-12-10 2010-11-18 Meditrina Pharmaceuticals, Inc. Treatment of Menorrhagia with Aromatase Inhibitor
GB0914767D0 (en) 2009-08-24 2009-09-30 Sterix Ltd Compound

Citations (1)

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EP0340153A1 (de) * 1988-03-31 1989-11-02 Schering Aktiengesellschaft N-substituierte Imidazole, Verfahren zu ihrer Herstellung sowie ihre Verwendung in Arzneimitteln

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US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
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US4617307A (en) * 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
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US4889861A (en) * 1982-12-21 1989-12-26 Ciba-Geigy Corp. Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors
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DE3714964A1 (de) * 1987-04-30 1988-11-10 Schering Ag 15-alkyl-19-thio-4-androsten-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
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GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
GB8716650D0 (en) * 1987-07-15 1987-08-19 Ici Plc Use of olefinic compounds
GB8721384D0 (en) * 1987-09-11 1987-10-21 Erba Farmitalia 17-substituted andro-sta-1 4-dien-3-one derivatives
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Patent Citations (1)

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EP0340153A1 (de) * 1988-03-31 1989-11-02 Schering Aktiengesellschaft N-substituierte Imidazole, Verfahren zu ihrer Herstellung sowie ihre Verwendung in Arzneimitteln

Also Published As

Publication number Publication date
GB2256137B (en) 1995-01-11
PT100409B (pt) 1999-10-29
AU1509292A (en) 1992-10-29
JPH05112467A (ja) 1993-05-07
ITRM920310A1 (it) 1993-10-24
CH683151A5 (de) 1994-01-31
US5583128A (en) 1996-12-10
IL101688A (en) 1997-01-10
AU654540B2 (en) 1994-11-10
DK53392D0 (da) 1992-04-24
PT100409A (pt) 1993-08-31
ZA922931B (en) 1993-04-28
IT1257474B (it) 1996-01-25
SE9201249D0 (sv) 1992-04-21
NO921575D0 (no) 1992-04-23
DK176332B1 (da) 2007-08-20
NO300156B1 (no) 1997-04-21
IE64875B1 (en) 1995-09-20
DK53392A (da) 1992-10-25
SE9201249L (sv) 1992-10-25
SE512618C2 (sv) 2000-04-10
NL9200755A (nl) 1992-11-16
CA2066807A1 (en) 1992-10-25
DE4213005A1 (de) 1992-10-29
JP3710830B2 (ja) 2005-10-26
PH30495A (en) 1997-05-28
CA2066807C (en) 2003-09-23
IE921318A1 (en) 1992-11-04
KR920019351A (ko) 1992-11-19
IL101688A0 (en) 1992-12-30
BE1005781A3 (fr) 1994-01-25
FR2675693B1 (fr) 1995-06-30
AT401873B (de) 1996-12-27
GB2256137A (en) 1992-12-02
KR100219017B1 (ko) 1999-09-01
NZ242443A (en) 1996-10-28
TW201267B (zh) 1993-03-01
MX9201908A (es) 1992-11-01
ATA83692A (de) 1996-05-15
LU88106A1 (de) 1993-12-06
NO921575L (no) 1992-10-26
GB9208718D0 (en) 1992-06-10
FR2675693A1 (fr) 1992-10-30
ITRM920310A0 (it) 1992-04-24

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: NOVARTIS AG, BASEL, CH

8110 Request for examination paragraph 44
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8339 Ceased/non-payment of the annual fee