DE3485693D1 - Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung. - Google Patents

Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung.

Info

Publication number
DE3485693D1
DE3485693D1 DE8484303783T DE3485693T DE3485693D1 DE 3485693 D1 DE3485693 D1 DE 3485693D1 DE 8484303783 T DE8484303783 T DE 8484303783T DE 3485693 T DE3485693 T DE 3485693T DE 3485693 D1 DE3485693 D1 DE 3485693D1
Authority
DE
Germany
Prior art keywords
igf
recombinant host
insulin
human
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8484303783T
Other languages
English (en)
Inventor
James Mon Lee
Axel Ullrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27053789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3485693(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE3485693D1 publication Critical patent/DE3485693D1/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE8484303783T 1983-06-06 1984-06-05 Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung. Revoked DE3485693D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50135383A 1983-06-06 1983-06-06
US50607883A 1983-06-20 1983-06-20

Publications (1)

Publication Number Publication Date
DE3485693D1 true DE3485693D1 (de) 1992-06-11

Family

ID=27053789

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484303783T Revoked DE3485693D1 (de) 1983-06-06 1984-06-05 Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung.

Country Status (10)

Country Link
US (3) US6331609B1 (de)
EP (1) EP0128733B1 (de)
JP (2) JP2608870B2 (de)
KR (1) KR850000525A (de)
AU (1) AU594301B2 (de)
DE (1) DE3485693D1 (de)
DK (1) DK172480B1 (de)
ES (1) ES8603955A1 (de)
IE (1) IE58317B1 (de)
IL (1) IL71991A (de)

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US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
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TW202233228A (zh) 2020-10-19 2022-09-01 美商舒爾人類基因療法公司 適用於新生兒的組成物
CN118574840A (zh) 2022-01-19 2024-08-30 奥克希尔生物有限公司 用于减少igf-1/igfbp的氧化的组合物和方法

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AU594301B2 (en) 1990-03-08
IE841400L (en) 1984-12-06
US6331609B1 (en) 2001-12-18
JPS6069029A (ja) 1985-04-19
DK276184D0 (da) 1984-06-04
KR850000525A (ko) 1985-02-27
EP0128733A1 (de) 1984-12-19
ES8603955A1 (es) 1986-01-16
JPH0759578A (ja) 1995-03-07
ES533170A0 (es) 1986-01-16
EP0128733B1 (de) 1992-05-06
DK172480B1 (da) 1998-10-05
JP2608870B2 (ja) 1997-05-14
IL71991A (en) 1994-05-30
US6331414B1 (en) 2001-12-18
IE58317B1 (en) 1993-09-08
IL71991A0 (en) 1984-10-31
AU2913384A (en) 1984-12-13
DK276184A (da) 1985-01-21
USRE39355E1 (en) 2006-10-17

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