IT1197708B - Composizione farmaceutica a base di antibiotici beta-lattamici,procedimento per prepararla e metodo per stabilizzarla - Google Patents

Composizione farmaceutica a base di antibiotici beta-lattamici,procedimento per prepararla e metodo per stabilizzarla

Info

Publication number
IT1197708B
IT1197708B IT48950/83A IT4895083A IT1197708B IT 1197708 B IT1197708 B IT 1197708B IT 48950/83 A IT48950/83 A IT 48950/83A IT 4895083 A IT4895083 A IT 4895083A IT 1197708 B IT1197708 B IT 1197708B
Authority
IT
Italy
Prior art keywords
stabilize
beta
prepare
procedure
pharmaceutical composition
Prior art date
Application number
IT48950/83A
Other languages
English (en)
Other versions
IT8348950A0 (it
Inventor
Betty Linda Richardson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT8348950A0 publication Critical patent/IT8348950A0/it
Application granted granted Critical
Publication of IT1197708B publication Critical patent/IT1197708B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
IT48950/83A 1982-09-10 1983-09-09 Composizione farmaceutica a base di antibiotici beta-lattamici,procedimento per prepararla e metodo per stabilizzarla IT1197708B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8225853 1982-09-10

Publications (2)

Publication Number Publication Date
IT8348950A0 IT8348950A0 (it) 1983-09-09
IT1197708B true IT1197708B (it) 1988-12-06

Family

ID=10532830

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48950/83A IT1197708B (it) 1982-09-10 1983-09-09 Composizione farmaceutica a base di antibiotici beta-lattamici,procedimento per prepararla e metodo per stabilizzarla

Country Status (20)

Country Link
US (2) US4582830A (it)
JP (1) JPS5973518A (it)
KR (1) KR880001094B1 (it)
AT (1) AT388671B (it)
AU (1) AU566245B2 (it)
BE (1) BE897721A (it)
CA (1) CA1215647A (it)
CH (1) CH655008A5 (it)
DE (1) DE3332616C2 (it)
DK (1) DK161304C (it)
ES (1) ES525492A0 (it)
FR (1) FR2532849B1 (it)
GB (1) GB2126479B (it)
IE (1) IE55720B1 (it)
IT (1) IT1197708B (it)
NL (1) NL189948C (it)
NZ (1) NZ205539A (it)
PT (1) PT77323B (it)
SE (1) SE464615B (it)
ZA (1) ZA836703B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626534A (en) * 1984-07-23 1986-12-02 Eli Lilly And Company Pharmaceutical formulation
AT393452B (de) * 1985-08-05 1991-10-25 Bristol Myers Squibb Co Verfahren zur herstellung eines cephalosporinpraeparates zur herstellung einer injektionsloesung
KR890701104A (ko) * 1987-05-27 1989-12-19 에지.지.제이.베르미렌, 에이.디.도우마 β-락탐 항생제의 급용해성 무수 조성물
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
DE69518666T2 (de) * 1994-12-08 2001-02-08 Otsuka Pharmaceutical Factory, Inc. Verfahren zum unterdrücken der adsorption von aus dem behältermaterial stammenden substanzen durch arzneimittel
HRP970281B1 (en) * 1996-05-28 2002-04-30 Merck & Co Inc Carbapenem antibiotic, composition and method of preparation
CA2239331C (en) * 1998-05-29 1999-11-30 Bernard Charles Sherman Pharmaceutical tablets comprising cefuroxime axetil
WO2004096279A1 (ja) * 2003-04-28 2004-11-11 Takeda Pharmaceutical Company Limited 注射用組成物
JP4700291B2 (ja) * 2003-04-28 2011-06-15 武田薬品工業株式会社 注射用組成物
EP1625859A1 (en) * 2004-08-13 2006-02-15 Access Group ApS A process for the preparation of a package comprising a sterilised bulk of a substance, and a package comprising a sterilised bulk of a penicilin
CN102920710B (zh) * 2012-11-16 2014-05-28 罗诚 一种头孢地嗪化合物的药物组合物
CN103432137B (zh) * 2013-08-28 2015-01-28 芦红代 头孢西丁的药物组合物
CN113350511B (zh) * 2021-03-01 2024-01-02 郎俊娜 一种新型注射用无菌粉末灌装混合保护气
CN116588404A (zh) * 2022-12-31 2023-08-15 浙江惠迪森药业有限公司 注射用无菌粉末灌装保护气制作方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB737242A (en) * 1952-10-16 1955-09-21 Novo Terapeutisk Labor As Process of increasing the physical stability of aqueous suspensions of penicillin compounds
GB760087A (en) * 1952-10-16 1956-10-31 Novo Terapeutisk Labor As Process of increasing the physical stability of aqueous suspensions of penicillin compounds
GB1132583A (en) * 1964-12-16 1968-11-06 Glaxo Lab Ltd Pharmaceutical compositions containing cephalosporins
GB1276839A (en) * 1968-08-02 1972-06-07 Sandoz Products Ltd Antibiotic compositions
AT307616B (de) * 1969-05-02 1973-05-25 Biochemie Gmbh Verfahren zur Herstellung einer Brausezubereitung
GB1380741A (en) * 1971-02-05 1975-01-15 Squibb & Sons Inc Antibiotic compositions and their preparation
US3940483A (en) * 1971-02-05 1976-02-24 E. R. Squibb & Sons, Inc. Antibiotic compositions and method
LU65921A1 (it) * 1972-08-18 1974-02-21
US4160829A (en) * 1972-12-22 1979-07-10 Gist-Brocades N.V. Antibacterial 1,2,4-oxadiazolylacetamido cephalosporins
US3969524A (en) * 1974-08-13 1976-07-13 Hoffmann-La Roche Inc. Stable amoxicillin dosage form
GB1463563A (en) * 1974-10-10 1977-02-02 Beecham Group Ltd Pharmaceutical compositions
DE2461969A1 (de) * 1974-12-31 1976-07-08 Behringwerke Ag Stabiles blutplasma, verfahren zu dessen herstellung und seine verwendung als vergleichsplasma bei gerinnungs- untersuchungen
CA1051780A (en) * 1975-04-09 1979-04-03 Bahram Farhadieh Stable chelocardin composition
GB1575905A (en) * 1976-04-28 1980-10-01 Glaxo Lab Ltd Salt of cefuroxime
GB1504767A (en) * 1976-08-23 1978-03-22 Beecham Group Ltd Antibiotic compositions
JPS5329936A (en) * 1976-08-31 1978-03-20 Takeda Chem Ind Ltd Antibiotic composition
FR2403078A1 (fr) * 1977-09-19 1979-04-13 Lafon Labor Nouveau procede de preparation de formes pharmaceutiques, cosmetiques ou de diagnostic
EP0001516A1 (en) * 1977-10-10 1979-04-18 Glaxo Group Limited Beta-Lactam compounds, processes for their preparation, pharmaceutical compositions containing them and intermediates of use in their preparation
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
PT70225A (en) * 1978-10-03 1979-10-01 Gist Brocades Nv Process for the preparation of sodium amoxicillin preparations
US4235900A (en) * 1978-11-15 1980-11-25 E. R. Squibb & Sons, Inc. Cephradine compositions
FR2445833A1 (fr) * 1979-01-04 1980-08-01 Chimie Biolog Nouveaux sels d'antibiotiques amines a cycle beta lactame
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic

Also Published As

Publication number Publication date
ATA322783A (de) 1989-01-15
JPH0480883B2 (it) 1992-12-21
IE832118L (en) 1984-03-10
AU1897583A (en) 1984-03-15
NZ205539A (en) 1986-03-14
US4582830A (en) 1986-04-15
GB8324133D0 (en) 1983-10-12
ZA836703B (en) 1984-10-31
SE8304857L (sv) 1984-03-11
GB2126479A (en) 1984-03-28
PT77323A (en) 1983-10-01
NL189948B (nl) 1993-04-16
ES8502863A1 (es) 1985-02-01
SE8304857D0 (sv) 1983-09-09
IT8348950A0 (it) 1983-09-09
DK409183D0 (da) 1983-09-09
CH655008A5 (de) 1986-03-27
DK161304C (da) 1991-12-02
AU566245B2 (en) 1987-10-15
KR880001094B1 (ko) 1988-06-29
BE897721A (fr) 1984-03-09
AT388671B (de) 1989-08-10
GB2126479B (en) 1986-04-03
NL8303125A (nl) 1984-04-02
PT77323B (en) 1986-02-06
ES525492A0 (es) 1985-02-01
FR2532849A1 (fr) 1984-03-16
NL189948C (nl) 1993-09-16
US4803196A (en) 1989-02-07
DE3332616C2 (de) 1995-06-01
KR840006126A (ko) 1984-11-22
CA1215647A (en) 1986-12-23
DK409183A (da) 1984-03-11
JPS5973518A (ja) 1984-04-25
IE55720B1 (en) 1991-01-02
DE3332616A1 (de) 1984-03-15
FR2532849B1 (fr) 1986-08-22
DK161304B (da) 1991-06-24
SE464615B (sv) 1991-05-27

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 217

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 217, 19920504; GLAXO GROUP LIMITED

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970829