GB1276839A - Antibiotic compositions - Google Patents

Antibiotic compositions

Info

Publication number
GB1276839A
GB1276839A GB3712368A GB3712368A GB1276839A GB 1276839 A GB1276839 A GB 1276839A GB 3712368 A GB3712368 A GB 3712368A GB 3712368 A GB3712368 A GB 3712368A GB 1276839 A GB1276839 A GB 1276839A
Authority
GB
United Kingdom
Prior art keywords
effervescent
antibiotic
compositions
acid
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3712368A
Inventor
Robert Foster Weir
Keith Robert Burton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharmaceuticals UK Ltd
Original Assignee
Sandoz Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Products Ltd filed Critical Sandoz Products Ltd
Priority to GB3712368A priority Critical patent/GB1276839A/en
Priority to AT426469A priority patent/AT308284B/en
Priority to DK382969A priority patent/DK127167B/en
Priority to DE19691938709 priority patent/DE1938709A1/en
Priority to ES370058A priority patent/ES370058A1/en
Priority to FR6926510A priority patent/FR2014956B1/fr
Priority to NL6911804A priority patent/NL6911804A/xx
Publication of GB1276839A publication Critical patent/GB1276839A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Abstract

1276839 Effervescent antibiotic compositions SANDOZ PRODUCTS Ltd 31 July 1969 [2 Aug 1968] 37123/68 Heading A5B Effervescent antibiotic compositions, in a form suitable for dissolution in water to produce an orally acceptable effervescent solution, comprise (i) an effervescent agent and (ii) an antibiotic which goes into solution when the effervescent composition is dissolved in water, which is acid-stable, and which is neither irritant to the stomach nor destroyed therein, from 1 to 60 parts by weight of (i) being present for each part by weight of (ii), the composition being in unit dosage form and containing from 1 to 4gms of effervescent agent when a surface active agent is present. The antibiotic may be a penicillin or a salt thereof, such as phenoxymethyl penicillin or its potassium salt, ampicillin, cloxacillin, oxacillin, phenethicillin, phenbenicillin, nafcillin, novobiocin, fusidic acid, chloramphenicol, colistin, lincomycin, spiramycin, neomycin, paromomycin, viomycin, streptomycin, methacycline, erythromycin, chlorotetracycline, oxytetracycline, tetracycline, lymecyline and cycloserine. The effervescent agent may comprise a pharmaceutically acceptable carbonate e.g. sodium or potassium carbonate or bicarbonate; and a substance which on dissolution in water forms an acid-reacting substance e.g. citric or tartaric acid. The compositions may also contain glucosamine. The compositions are preferably in the form of tablets or sachets.
GB3712368A 1968-08-02 1968-08-02 Antibiotic compositions Expired GB1276839A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GB3712368A GB1276839A (en) 1968-08-02 1968-08-02 Antibiotic compositions
AT426469A AT308284B (en) 1968-08-02 1969-05-02 Process for making an effervescent preparation
DK382969A DK127167B (en) 1968-08-02 1969-07-15 Process for the preparation of a pharmaceutical effervescent composition of penicillin compounds.
DE19691938709 DE1938709A1 (en) 1968-08-02 1969-07-30 New compositions containing antibiotics
ES370058A ES370058A1 (en) 1968-08-02 1969-07-30 Antibiotic compositions
FR6926510A FR2014956B1 (en) 1968-08-02 1969-08-01
NL6911804A NL6911804A (en) 1968-08-02 1969-08-01

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3712368A GB1276839A (en) 1968-08-02 1968-08-02 Antibiotic compositions

Publications (1)

Publication Number Publication Date
GB1276839A true GB1276839A (en) 1972-06-07

Family

ID=10393920

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3712368A Expired GB1276839A (en) 1968-08-02 1968-08-02 Antibiotic compositions

Country Status (7)

Country Link
AT (1) AT308284B (en)
DE (1) DE1938709A1 (en)
DK (1) DK127167B (en)
ES (1) ES370058A1 (en)
FR (1) FR2014956B1 (en)
GB (1) GB1276839A (en)
NL (1) NL6911804A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2532849A1 (en) * 1982-09-10 1984-03-16 Glaxo Group Ltd SOLID PHARMACEUTICAL COMPOSITION CONTAINING B-LACTAMIC ANTIBIOTICS, PROCESS FOR PREPARING THE SAME AND METHOD FOR STABILIZING A PHARMACEUTICAL COMPOSITION
US5223246A (en) * 1990-02-14 1993-06-29 Takeda Chemical Industries, Ltd. Effervescent composition, its production and use
US6051254A (en) * 1990-04-07 2000-04-18 Smithkline Beecham Plc Pharmaceutical formulation
US6488961B1 (en) 1996-09-20 2002-12-03 Ethypharm, Inc. Effervescent granules and methods for their preparation
EP1728511A1 (en) * 2005-05-31 2006-12-06 Faust Pharmaceuticals New use of phenethicillin and salts thereof.
WO2007147125A2 (en) * 2006-06-15 2007-12-21 Serenex, Inc. Tetracycline package formulations
WO2007147133A1 (en) * 2006-06-15 2007-12-21 Serenex, Inc. Stabilized tetracycline compositions
WO2008085310A2 (en) * 2006-12-19 2008-07-17 Schering-Plough Ltd. Effervescent formulations of florfenicol for addition in drinking water systems
CN102670646A (en) * 2012-05-07 2012-09-19 河南省康星药业有限公司 Cattle effervescent tablet taking lincomycin hydrochloride as main component and preparation process for effervescent tablet
WO2016097754A1 (en) * 2014-12-18 2016-06-23 Helperby Therapeutics Limited Novel combination and use
CN109453192A (en) * 2018-12-06 2019-03-12 沧州爱农生物科技有限公司 A kind of compound hydrochloric acid terramycin alumen borneol effervescent tablet and preparation method thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1291281A (en) * 1969-03-20 1972-10-04 Pfizer Ltd Improvements in pharmaceutical compositions
DE4420735C2 (en) * 1994-06-15 1996-09-05 Allphamed Arzneimittel Gmbh Process for the production of mechanically stable, high-speed effervescent tablets

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US131123A (en) * 1872-09-03 Improvement in combined dental pluggers and burring-tools

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2532849A1 (en) * 1982-09-10 1984-03-16 Glaxo Group Ltd SOLID PHARMACEUTICAL COMPOSITION CONTAINING B-LACTAMIC ANTIBIOTICS, PROCESS FOR PREPARING THE SAME AND METHOD FOR STABILIZING A PHARMACEUTICAL COMPOSITION
GB2126479A (en) * 1982-09-10 1984-03-28 Glaxo Group Ltd Pharmaceutical-compositions in inert carbon dioxide atmosphere
US5223246A (en) * 1990-02-14 1993-06-29 Takeda Chemical Industries, Ltd. Effervescent composition, its production and use
US6051254A (en) * 1990-04-07 2000-04-18 Smithkline Beecham Plc Pharmaceutical formulation
US6077536A (en) * 1990-04-07 2000-06-20 Beecham Group Plc Pharmaceutical formulation
US6488961B1 (en) 1996-09-20 2002-12-03 Ethypharm, Inc. Effervescent granules and methods for their preparation
EP1728511A1 (en) * 2005-05-31 2006-12-06 Faust Pharmaceuticals New use of phenethicillin and salts thereof.
WO2007147133A1 (en) * 2006-06-15 2007-12-21 Serenex, Inc. Stabilized tetracycline compositions
WO2007147125A2 (en) * 2006-06-15 2007-12-21 Serenex, Inc. Tetracycline package formulations
WO2007147125A3 (en) * 2006-06-15 2008-02-28 Serenex Inc Tetracycline package formulations
WO2008085310A2 (en) * 2006-12-19 2008-07-17 Schering-Plough Ltd. Effervescent formulations of florfenicol for addition in drinking water systems
WO2008085310A3 (en) * 2006-12-19 2008-08-21 Schering Plough Ltd Effervescent formulations of florfenicol for addition in drinking water systems
CN102670646A (en) * 2012-05-07 2012-09-19 河南省康星药业有限公司 Cattle effervescent tablet taking lincomycin hydrochloride as main component and preparation process for effervescent tablet
CN102670646B (en) * 2012-05-07 2014-01-22 河南省康星药业股份有限公司 Cattle effervescent tablet taking lincomycin hydrochloride as main component and preparation process for effervescent tablet
WO2016097754A1 (en) * 2014-12-18 2016-06-23 Helperby Therapeutics Limited Novel combination and use
JP2018503614A (en) * 2014-12-18 2018-02-08 ヘルパービー セラピューティクス リミテッドＨｅｌｐｅｒｂｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ New combinations and uses
US10335454B2 (en) 2014-12-18 2019-07-02 Helperby Therapeutics Limited Combination and use
JP2020033385A (en) * 2014-12-18 2020-03-05 ヘルパービー セラピューティクス リミテッドＨｅｌｐｅｒｂｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ Therapeutic agents for microbial infections
CN109453192A (en) * 2018-12-06 2019-03-12 沧州爱农生物科技有限公司 A kind of compound hydrochloric acid terramycin alumen borneol effervescent tablet and preparation method thereof

Also Published As

Publication number Publication date
AT308284B (en) 1973-06-25
DE1938709A1 (en) 1970-04-02
NL6911804A (en) 1970-02-04
ES370058A1 (en) 1971-12-01
DK127167B (en) 1973-10-01
FR2014956B1 (en) 1973-01-12
FR2014956A1 (en) 1970-04-24

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees