DE3428945A1 - 4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung - Google Patents

4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung

Info

Publication number
DE3428945A1
DE3428945A1 DE3428945A DE3428945A DE3428945A1 DE 3428945 A1 DE3428945 A1 DE 3428945A1 DE 3428945 A DE3428945 A DE 3428945A DE 3428945 A DE3428945 A DE 3428945A DE 3428945 A1 DE3428945 A1 DE 3428945A1
Authority
DE
Germany
Prior art keywords
deoxy
group
general formula
hydrogen atom
anthracycline glycoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE3428945A
Other languages
German (de)
English (en)
Inventor
Federico Nerviano Arcamone
Fernando Cassina de'Pecchi Giuliani
Sergio Mailand/Milano Penco
Antonino Suarato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SpA Mailand/milano
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SpA Mailand/milano, Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SpA Mailand/milano
Publication of DE3428945A1 publication Critical patent/DE3428945A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE3428945A 1983-08-11 1984-08-06 4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung Withdrawn DE3428945A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838321676A GB8321676D0 (en) 1983-08-11 1983-08-11 4'-haloanthrocycline glycosides

Publications (1)

Publication Number Publication Date
DE3428945A1 true DE3428945A1 (de) 1985-02-28

Family

ID=10547171

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3428945A Withdrawn DE3428945A1 (de) 1983-08-11 1984-08-06 4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung

Country Status (19)

Country Link
JP (1) JPS6058997A (da)
AT (1) AT384226B (da)
AU (1) AU563396B2 (da)
BE (1) BE900336A (da)
CA (1) CA1250833A (da)
CH (1) CH660740A5 (da)
CS (1) CS270411B2 (da)
DE (1) DE3428945A1 (da)
DK (1) DK381884A (da)
FI (1) FI78109C (da)
FR (1) FR2554450B1 (da)
GB (2) GB8321676D0 (da)
GR (1) GR80046B (da)
HU (1) HU194266B (da)
IT (1) IT1209576B (da)
NL (1) NL8402477A (da)
SE (1) SE8404005L (da)
SU (1) SU1579465A3 (da)
ZA (1) ZA846147B (da)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520469A1 (de) * 1984-06-08 1985-12-12 Farmitalia Carlo Erba S.p.A., Mailand/Milano Neue anthracycline, verfahren zu deren herstellung, zwischenverbindungen und pharmazeutische zubereitung
DE3912867A1 (de) * 1988-04-22 1989-11-02 Erba Carlo Spa 4-desmethoxy-4'-desoxy-4'-jodoanthracyclinglycoside und verfahren zu deren herstellung
WO1996007665A1 (en) * 1994-09-09 1996-03-14 Pharmacia S.P.A. Anthracycline derivatives

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2159518A (en) * 1984-06-08 1985-12-04 Erba Farmitalia New anthracyclines and process for manufacture
DE3500017A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-haloanthracyclinester
AU601857B2 (en) * 1988-06-30 1990-09-20 Pharmacia & Upjohn S.P.A. A new antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
MA21995A1 (fr) * 1989-11-13 1991-07-01 Menarini Farma Ind Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892943A (fr) * 1942-03-06 1944-05-24 Ig Farbenindustrie Ag Procédé pour épurer la dilactone gamma céto-pimélique
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520469A1 (de) * 1984-06-08 1985-12-12 Farmitalia Carlo Erba S.p.A., Mailand/Milano Neue anthracycline, verfahren zu deren herstellung, zwischenverbindungen und pharmazeutische zubereitung
DE3912867A1 (de) * 1988-04-22 1989-11-02 Erba Carlo Spa 4-desmethoxy-4'-desoxy-4'-jodoanthracyclinglycoside und verfahren zu deren herstellung
WO1996007665A1 (en) * 1994-09-09 1996-03-14 Pharmacia S.P.A. Anthracycline derivatives

Also Published As

Publication number Publication date
GB8420237D0 (en) 1984-09-12
NL8402477A (nl) 1985-03-01
DK381884D0 (da) 1984-08-08
FI78109B (fi) 1989-02-28
GB2144744B (en) 1986-12-03
CS270411B2 (en) 1990-06-13
CS605284A2 (en) 1989-11-14
FR2554450A1 (fr) 1985-05-10
SU1579465A3 (ru) 1990-07-15
ZA846147B (en) 1985-03-27
CA1250833A (en) 1989-03-07
DK381884A (da) 1985-02-12
SE8404005D0 (sv) 1984-08-07
GR80046B (en) 1984-12-10
HU194266B (en) 1988-01-28
JPS6058997A (ja) 1985-04-05
AT384226B (de) 1987-10-12
FI78109C (fi) 1989-06-12
SE8404005L (sv) 1985-02-12
IT8422232A0 (it) 1984-08-06
ATA253884A (de) 1987-03-15
FR2554450B1 (fr) 1987-01-30
AU563396B2 (en) 1987-07-09
BE900336A (fr) 1985-02-11
AU3168584A (en) 1985-02-14
FI843110A0 (fi) 1984-08-08
GB2144744A (en) 1985-03-13
HUT35691A (en) 1985-07-29
GB8321676D0 (en) 1983-09-14
FI843110A (fi) 1985-02-12
IT1209576B (it) 1989-08-30
CH660740A5 (de) 1987-06-15

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: FARMITALIA CARLO ERBA S.R.L., MAILAND/MILANO, IT

8128 New person/name/address of the agent

Representative=s name: EITLE, W., DIPL.-ING. HOFFMANN, K., DIPL.-ING. DR.

8139 Disposal/non-payment of the annual fee