CA1250833A - Process for preparing 4'-haloanthracycline glycosides - Google Patents

Process for preparing 4'-haloanthracycline glycosides

Info

Publication number
CA1250833A
CA1250833A CA000460796A CA460796A CA1250833A CA 1250833 A CA1250833 A CA 1250833A CA 000460796 A CA000460796 A CA 000460796A CA 460796 A CA460796 A CA 460796A CA 1250833 A CA1250833 A CA 1250833A
Authority
CA
Canada
Prior art keywords
process according
compound
reaction
group
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000460796A
Other languages
English (en)
French (fr)
Inventor
Federico Arcamone
Fernando Giuliani
Sergio Penco
Antonino Suarato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of CA1250833A publication Critical patent/CA1250833A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
CA000460796A 1983-08-11 1984-08-10 Process for preparing 4'-haloanthracycline glycosides Expired CA1250833A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838321676A GB8321676D0 (en) 1983-08-11 1983-08-11 4'-haloanthrocycline glycosides
GB8321676 1983-08-11

Publications (1)

Publication Number Publication Date
CA1250833A true CA1250833A (en) 1989-03-07

Family

ID=10547171

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000460796A Expired CA1250833A (en) 1983-08-11 1984-08-10 Process for preparing 4'-haloanthracycline glycosides

Country Status (19)

Country Link
JP (1) JPS6058997A (da)
AT (1) AT384226B (da)
AU (1) AU563396B2 (da)
BE (1) BE900336A (da)
CA (1) CA1250833A (da)
CH (1) CH660740A5 (da)
CS (1) CS270411B2 (da)
DE (1) DE3428945A1 (da)
DK (1) DK381884A (da)
FI (1) FI78109C (da)
FR (1) FR2554450B1 (da)
GB (2) GB8321676D0 (da)
GR (1) GR80046B (da)
HU (1) HU194266B (da)
IT (1) IT1209576B (da)
NL (1) NL8402477A (da)
SE (1) SE8404005L (da)
SU (1) SU1579465A3 (da)
ZA (1) ZA846147B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2159518A (en) * 1984-06-08 1985-12-04 Erba Farmitalia New anthracyclines and process for manufacture
GB8414619D0 (en) * 1984-06-08 1984-07-11 Erba Farmitalia Anthracyclines
DE3500017A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-haloanthracyclinester
GB2218087B (en) * 1988-04-22 1991-01-30 Erba Carlo Spa 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides
AU601857B2 (en) * 1988-06-30 1990-09-20 Pharmacia & Upjohn S.P.A. A new antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
MA21995A1 (fr) * 1989-11-13 1991-07-01 Menarini Farma Ind Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892943A (fr) * 1942-03-06 1944-05-24 Ig Farbenindustrie Ag Procédé pour épurer la dilactone gamma céto-pimélique
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides

Also Published As

Publication number Publication date
GB8420237D0 (en) 1984-09-12
NL8402477A (nl) 1985-03-01
DK381884D0 (da) 1984-08-08
FI78109B (fi) 1989-02-28
GB2144744B (en) 1986-12-03
CS270411B2 (en) 1990-06-13
CS605284A2 (en) 1989-11-14
FR2554450A1 (fr) 1985-05-10
SU1579465A3 (ru) 1990-07-15
ZA846147B (en) 1985-03-27
DE3428945A1 (de) 1985-02-28
DK381884A (da) 1985-02-12
SE8404005D0 (sv) 1984-08-07
GR80046B (en) 1984-12-10
HU194266B (en) 1988-01-28
JPS6058997A (ja) 1985-04-05
AT384226B (de) 1987-10-12
FI78109C (fi) 1989-06-12
SE8404005L (sv) 1985-02-12
IT8422232A0 (it) 1984-08-06
ATA253884A (de) 1987-03-15
FR2554450B1 (fr) 1987-01-30
AU563396B2 (en) 1987-07-09
BE900336A (fr) 1985-02-11
AU3168584A (en) 1985-02-14
FI843110A0 (fi) 1984-08-08
GB2144744A (en) 1985-03-13
HUT35691A (en) 1985-07-29
GB8321676D0 (en) 1983-09-14
FI843110A (fi) 1985-02-12
IT1209576B (it) 1989-08-30
CH660740A5 (de) 1987-06-15

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Legal Events

Date Code Title Description
MKEX Expiry