DE2926828A1 - Verfahren zur herstellung von n,n'- disubstituierten 2-naphthalinaethanimidamiden und ihren salzen und 2-nphthylimidoessigsaeureestersalze - Google Patents

Verfahren zur herstellung von n,n'- disubstituierten 2-naphthalinaethanimidamiden und ihren salzen und 2-nphthylimidoessigsaeureestersalze

Info

Publication number
DE2926828A1
DE2926828A1 DE19792926828 DE2926828A DE2926828A1 DE 2926828 A1 DE2926828 A1 DE 2926828A1 DE 19792926828 DE19792926828 DE 19792926828 DE 2926828 A DE2926828 A DE 2926828A DE 2926828 A1 DE2926828 A1 DE 2926828A1
Authority
DE
Germany
Prior art keywords
general formula
salts
carbon atoms
formula iii
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19792926828
Other languages
German (de)
English (en)
Inventor
James Ray Mccarthy
Jun Albert Joseph Schuster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of DE2926828A1 publication Critical patent/DE2926828A1/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/20—Polycyclic condensed hydrocarbons
    • C07C15/24—Polycyclic condensed hydrocarbons containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19792926828 1978-07-03 1979-07-03 Verfahren zur herstellung von n,n'- disubstituierten 2-naphthalinaethanimidamiden und ihren salzen und 2-nphthylimidoessigsaeureestersalze Ceased DE2926828A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92169078A 1978-07-03 1978-07-03

Publications (1)

Publication Number Publication Date
DE2926828A1 true DE2926828A1 (de) 1980-01-17

Family

ID=25445831

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792926828 Ceased DE2926828A1 (de) 1978-07-03 1979-07-03 Verfahren zur herstellung von n,n'- disubstituierten 2-naphthalinaethanimidamiden und ihren salzen und 2-nphthylimidoessigsaeureestersalze

Country Status (12)

Country Link
JP (1) JPS559095A (en, 2012)
AR (1) AR230619A1 (en, 2012)
BE (1) BE877449A (en, 2012)
CA (1) CA1130305A (en, 2012)
CH (1) CH641764A5 (en, 2012)
DE (1) DE2926828A1 (en, 2012)
DK (1) DK273079A (en, 2012)
ES (1) ES482113A1 (en, 2012)
FR (1) FR2430414A1 (en, 2012)
GB (1) GB2024223B (en, 2012)
IT (1) IT1121792B (en, 2012)
NL (1) NL7904774A (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495108A (en) * 1983-03-11 1985-01-22 E. I. Du Pont De Nemours And Company Process for preparing dialkyl propanediimidate dihydrohalides
US5180379A (en) * 1991-04-04 1993-01-19 Minnesota Mining And Manufacturing Company Electrode with pre-wired leads
JPH08293371A (ja) * 1995-04-20 1996-11-05 Nippon Denki Factory Eng Kk Ｉｃソケット

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1468926A1 (de) * 1964-07-31 1969-02-20 Rhone Poulenc Sa Verfahren zur Herstellung von neuen Acetamidinderivaten
DE1951258A1 (de) * 1968-10-17 1970-11-05 Lilly Co Eli Beta-Naphthylacetamidin und dessen Salze
US3742000A (en) * 1969-06-03 1973-06-26 Grace W R & Co Imidoether and amidine derivatives of substituted fatty amides
DE1817861B2 (de) * 1967-11-29 1973-09-06 Orsymonde, Paris N-alkylierte 3,4-methylendioxymandelsaeureamidine und deren pharmakologisch nicht giftige saeureanlagerungssalze und diese enthaltende pharmazeutische mittel
DD109864A1 (en, 2012) * 1973-11-20 1974-11-20
DE2449840A1 (de) * 1973-10-19 1975-04-24 Kao Corp Adamantylamidine und verfahren zu ihrer herstellung
DE2019307B2 (de) * 1969-04-24 1979-09-27 Orsymonde S.A., Paris Mandelamidinderivate und sie enthaltende Arzneimittel
DE2542791C2 (de) * 1974-10-02 1984-11-08 The Dow Chemical Co., Midland, Mich. N,N'-Disubstituierte Naphthylacetamidine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5198201A (en) * 1975-02-18 1976-08-30 n22 chikan omega amijino arufua aminosanjudotaimataha sonosanfukaenno seizoho

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1468926A1 (de) * 1964-07-31 1969-02-20 Rhone Poulenc Sa Verfahren zur Herstellung von neuen Acetamidinderivaten
DE1817861B2 (de) * 1967-11-29 1973-09-06 Orsymonde, Paris N-alkylierte 3,4-methylendioxymandelsaeureamidine und deren pharmakologisch nicht giftige saeureanlagerungssalze und diese enthaltende pharmazeutische mittel
DE1951258A1 (de) * 1968-10-17 1970-11-05 Lilly Co Eli Beta-Naphthylacetamidin und dessen Salze
DE2019307B2 (de) * 1969-04-24 1979-09-27 Orsymonde S.A., Paris Mandelamidinderivate und sie enthaltende Arzneimittel
US3742000A (en) * 1969-06-03 1973-06-26 Grace W R & Co Imidoether and amidine derivatives of substituted fatty amides
DE2449840A1 (de) * 1973-10-19 1975-04-24 Kao Corp Adamantylamidine und verfahren zu ihrer herstellung
DD109864A1 (en, 2012) * 1973-11-20 1974-11-20
DE2542791C2 (de) * 1974-10-02 1984-11-08 The Dow Chemical Co., Midland, Mich. N,N'-Disubstituierte Naphthylacetamidine

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
J.Pharm.Sci. 62 (1973), S.1899-1900 *
Pharmazie 28 (1973), S.427-431 *
Pharmazie 28 (1973), S.724-729 *
Pharmazie 29 (1974), S.263-267 *

Also Published As

Publication number Publication date
FR2430414B1 (en, 2012) 1984-06-08
GB2024223A (en) 1980-01-09
GB2024223B (en) 1982-07-14
AR230619A1 (es) 1984-05-31
JPS559095A (en) 1980-01-22
CA1130305A (en) 1982-08-24
JPS6343382B2 (en, 2012) 1988-08-30
BE877449A (fr) 1980-01-03
CH641764A5 (fr) 1984-03-15
DK273079A (da) 1980-01-04
ES482113A1 (es) 1980-04-01
NL7904774A (nl) 1980-01-07
IT7923509A0 (it) 1979-06-13
FR2430414A1 (fr) 1980-02-01
IT1121792B (it) 1986-04-23

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Legal Events

Date Code Title Description
OI Miscellaneous see part 1
8110 Request for examination paragraph 44
8131 Rejection