CA1130305A - Process for the preparation of n,n'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein - Google Patents

Process for the preparation of n,n'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein

Info

Publication number
CA1130305A
CA1130305A CA330,828A CA330828A CA1130305A CA 1130305 A CA1130305 A CA 1130305A CA 330828 A CA330828 A CA 330828A CA 1130305 A CA1130305 A CA 1130305A
Authority
CA
Canada
Prior art keywords
formula
carbon atoms
naphthylacetonitrile
hydroxy
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA330,828A
Other languages
English (en)
French (fr)
Inventor
Albert J. Schuster, Jr.
James R. Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of CA1130305A publication Critical patent/CA1130305A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/20—Polycyclic condensed hydrocarbons
    • C07C15/24—Polycyclic condensed hydrocarbons containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA330,828A 1978-07-03 1979-06-29 Process for the preparation of n,n'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein Expired CA1130305A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92169078A 1978-07-03 1978-07-03
US921,690 1978-07-03

Publications (1)

Publication Number Publication Date
CA1130305A true CA1130305A (en) 1982-08-24

Family

ID=25445831

Family Applications (1)

Application Number Title Priority Date Filing Date
CA330,828A Expired CA1130305A (en) 1978-07-03 1979-06-29 Process for the preparation of n,n'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein

Country Status (12)

Country Link
JP (1) JPS559095A (en, 2012)
AR (1) AR230619A1 (en, 2012)
BE (1) BE877449A (en, 2012)
CA (1) CA1130305A (en, 2012)
CH (1) CH641764A5 (en, 2012)
DE (1) DE2926828A1 (en, 2012)
DK (1) DK273079A (en, 2012)
ES (1) ES482113A1 (en, 2012)
FR (1) FR2430414A1 (en, 2012)
GB (1) GB2024223B (en, 2012)
IT (1) IT1121792B (en, 2012)
NL (1) NL7904774A (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495108A (en) * 1983-03-11 1985-01-22 E. I. Du Pont De Nemours And Company Process for preparing dialkyl propanediimidate dihydrohalides
US5180379A (en) * 1991-04-04 1993-01-19 Minnesota Mining And Manufacturing Company Electrode with pre-wired leads
JPH08293371A (ja) * 1995-04-20 1996-11-05 Nippon Denki Factory Eng Kk Ｉｃソケット

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1434131A (fr) * 1964-07-31 1966-04-08 Usines Rhone Poulenc Soc D Nouveaux dérivés de l'acétamidine
GB1243186A (en) * 1967-11-29 1971-08-18 Orsymonde Improvements in or relating to mandelamidine derivatives
ZA696719B (en) * 1968-10-17 1971-04-28 Lilly Co Eli 13-manphthylacetamidine and salts thereof
FR2036973A1 (en, 2012) * 1969-04-24 1970-12-31 Orsymonde
US3742000A (en) * 1969-06-03 1973-06-26 Grace W R & Co Imidoether and amidine derivatives of substituted fatty amides
JPS5246949B2 (en, 2012) * 1973-10-19 1977-11-29
DD109864A1 (en, 2012) * 1973-11-20 1974-11-20
US3903163A (en) * 1974-10-02 1975-09-02 Dow Chemical Co N,N-Disubstituted naphthaleneacetamidines
JPS5198201A (en) * 1975-02-18 1976-08-30 n22 chikan omega amijino arufua aminosanjudotaimataha sonosanfukaenno seizoho

Also Published As

Publication number Publication date
FR2430414B1 (en, 2012) 1984-06-08
GB2024223A (en) 1980-01-09
GB2024223B (en) 1982-07-14
AR230619A1 (es) 1984-05-31
JPS559095A (en) 1980-01-22
JPS6343382B2 (en, 2012) 1988-08-30
BE877449A (fr) 1980-01-03
CH641764A5 (fr) 1984-03-15
DE2926828A1 (de) 1980-01-17
DK273079A (da) 1980-01-04
ES482113A1 (es) 1980-04-01
NL7904774A (nl) 1980-01-07
IT7923509A0 (it) 1979-06-13
FR2430414A1 (fr) 1980-02-01
IT1121792B (it) 1986-04-23

Similar Documents

Publication Publication Date Title
CA1130305A (en) Process for the preparation of n,n'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein
NO783559L (no) Fremgangsmaate til fremstilling av 2,6-diaminonebulariner
CA1223265A (en) Process for preparing 1,2,4-triazole-3-carboxamides
US5461157A (en) Process for preparing pyrrolidinylacetamide derivatives
US4189444A (en) Process for the preparation of N,N'-disubstituted 2-naphthaleneethanimidamide and intermediates used therein
KR960002371B1 (ko) 1-프로파르길-2,4-디옥소이미다졸리딘의 제조중간체 및 그 제조방법
US4017512A (en) Process for producing N-alkylhydroxylamines
KR20010005943A (ko) 0-(3-아미노-2-히드록시-프로필)-히드록심산할라이드의 제조방법
US6147215A (en) Process for producing 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof
US4374266A (en) Ammonium salts of fluorophthalamic acids and method of preparation
NZ202857A (en) Preparation of beta-((2-methylpropoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate
US4062891A (en) N-formyl-2,3,5,6-dibenzobicyclo[5.1.0]octan-4-methylamine
EP0483674B1 (en) A process for producing an aliphatic amide and salts thereof
HU207718B (en) Process for producing 3,5,6-trichloropyridin-2-ol
EP0853077B1 (en) Process for producing alkyl 3-amino-4-substituted benzoates
CA1119179A (en) Process for preparing n-tritylimidazole compounds
US5081268A (en) Process for the preparation of oxetanes from 1,3-glycol monosulfates
SU978724A3 (ru) Способ получени 1-(2,6-диметилфенокси)-2-азидопропана
KR940009935B1 (ko) N-벤조일-c-티오펜옥시이미도일 클로라이드 유도체 및 그 제조방법
US5550288A (en) Process for the preparation of α-aminoacylanilides
US4229375A (en) 1-Aminomethyltricyclo[4.3.1.12,5 ]undecane and acid-addition salts thereof
KR950011118B1 (ko) 유기 n-히드록시이미데이트의 제조방법
KR960010101B1 (ko) 4-오르소토릴티오세미카바지드의 제조방법
US2538139A (en) Biotin derivatives and processes of preparing the same
US4612395A (en) Process for the production of N-(2-methyl-4-chlorophenyl)-formamidine derivatives

Legal Events

Date Code Title Description
MKEX Expiry