DE2462376A1 - Antibiotika und verfahren zu ihrer herstellung - Google Patents

Antibiotika und verfahren zu ihrer herstellung

Info

Publication number
DE2462376A1
DE2462376A1 DE19742462376 DE2462376A DE2462376A1 DE 2462376 A1 DE2462376 A1 DE 2462376A1 DE 19742462376 DE19742462376 DE 19742462376 DE 2462376 A DE2462376 A DE 2462376A DE 2462376 A1 DE2462376 A1 DE 2462376A1
Authority
DE
Germany
Prior art keywords
acid
solution
syn
added
stirred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19742462376
Other languages
German (de)
English (en)
Inventor
Janice Bradshaw
Martin Christopher Cook
Gordon Ian Gregory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10410683&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE2462376(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE2462376A1 publication Critical patent/DE2462376A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DE19742462376 1973-08-21 1974-08-20 Antibiotika und verfahren zu ihrer herstellung Pending DE2462376A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3964573A GB1453049A (en) 1973-08-21 1973-08-21 Cephalosporing antibiotics

Publications (1)

Publication Number Publication Date
DE2462376A1 true DE2462376A1 (de) 1976-11-25

Family

ID=10410683

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2439880A Expired DE2439880C3 (de) 1973-08-21 1974-08-20 (6R, 7R)-3-Carbamoyloxymethyl-7- [2-(fur-2-yl)-2methoxyiminoacetamido] -ceph-S-em^carbonsäure und Verfahren zur ihrer Herstellung
DE19742462376 Pending DE2462376A1 (de) 1973-08-21 1974-08-20 Antibiotika und verfahren zu ihrer herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2439880A Expired DE2439880C3 (de) 1973-08-21 1974-08-20 (6R, 7R)-3-Carbamoyloxymethyl-7- [2-(fur-2-yl)-2methoxyiminoacetamido] -ceph-S-em^carbonsäure und Verfahren zur ihrer Herstellung

Country Status (32)

Country Link
JP (2) JPS562077B2 (ja)
AR (2) AR212076A1 (ja)
AT (1) AT340042B (ja)
AU (1) AU473550B2 (ja)
BE (1) BE819004R (ja)
BG (2) BG23903A3 (ja)
CA (1) CA1057283A (ja)
CH (2) CH613975A5 (ja)
CS (2) CS204988B2 (ja)
CY (1) CY945A (ja)
DD (1) DD114417A5 (ja)
DE (2) DE2439880C3 (ja)
DK (1) DK147683C (ja)
ES (2) ES429388A1 (ja)
FI (1) FI65623C (ja)
FR (1) FR2241318B2 (ja)
GB (1) GB1453049A (ja)
GT (1) GT198302370A (ja)
HK (1) HK17378A (ja)
HU (1) HU170000B (ja)
IE (1) IE39764B1 (ja)
IL (1) IL45505A (ja)
KE (1) KE2816A (ja)
LU (2) LU88269I2 (ja)
MY (1) MY7800188A (ja)
NL (1) NL154741B (ja)
NO (1) NO152751C (ja)
PL (2) PL115805B1 (ja)
RO (2) RO64129A (ja)
SU (1) SU633483A3 (ja)
YU (2) YU36737B (ja)
ZA (1) ZA745331B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1897959A1 (en) * 2002-11-22 2008-03-12 The Johns Hopkins University Target for therapy of cognitive impairment

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
FI771866A (ja) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
FR2414509A1 (fr) * 1978-01-17 1979-08-10 Glaxo Group Ltd Procede de cristallisation de cefuroxime sodique
DE2804040C3 (de) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Cephemverbindungen
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
IT1190734B (it) * 1982-03-11 1988-02-24 Opos Biochimica Srl Procedimento per la preparazione di cefuroxima e intermedi impiegati in tale procedimento
GB8320520D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
WO2000053609A1 (en) * 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime
WO2004050663A2 (en) * 2002-12-05 2004-06-17 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefuroxime sodium
JP2008275173A (ja) * 2008-08-04 2008-11-13 Toshiba Corp 分岐配管
EP2741750A1 (en) 2011-08-12 2014-06-18 Dhanuka Laboratories Ltd. Pharmaceutical composition comprising cefuroxime
WO2013038323A1 (en) 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
KR101497420B1 (ko) 2013-07-05 2015-03-03 삼성중공업 주식회사 증발가스 저감용 액화천연가스 수송장치
CN105884799A (zh) * 2015-09-23 2016-08-24 石药集团中诺药业（石家庄）有限公司 一种新的头孢呋辛钠化合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1897959A1 (en) * 2002-11-22 2008-03-12 The Johns Hopkins University Target for therapy of cognitive impairment

Also Published As

Publication number Publication date
DK443274A (ja) 1975-04-28
LU70765A1 (ja) 1975-12-09
CH615931A5 (en) 1980-02-29
ES437269A1 (es) 1977-01-01
FI65623C (fi) 1984-06-11
JPS5649388A (en) 1981-05-02
CS204988B2 (en) 1981-04-30
IE39764B1 (en) 1978-12-20
IL45505A (en) 1979-01-31
ZA745331B (en) 1975-10-29
PL98962B1 (pl) 1978-06-30
CH613975A5 (en) 1979-10-31
BE819004R (fr) 1975-02-20
HK17378A (en) 1978-04-07
YU41231B (en) 1986-12-31
DD114417A5 (ja) 1975-08-05
HU170000B (ja) 1977-03-28
JPS562077B2 (ja) 1981-01-17
GB1453049A (en) 1976-10-20
YU30781A (en) 1983-02-28
CA1057283A (en) 1979-06-26
IL45505A0 (en) 1974-11-29
ES429388A1 (es) 1976-08-16
FI65623B (fi) 1984-02-29
AT340042B (de) 1977-11-25
DE2439880B2 (de) 1979-02-22
NO152751C (no) 1985-11-13
NL154741B (nl) 1977-10-17
BG23903A3 (en) 1977-11-10
AR212076A1 (es) 1978-05-15
JPS5052083A (ja) 1975-05-09
NO742986L (ja) 1975-03-17
BG25801A3 (en) 1978-12-12
MY7800188A (en) 1978-12-31
LU88269I2 (ja) 1994-02-03
NL7411095A (nl) 1975-02-25
YU228374A (en) 1982-06-18
NO152751B (no) 1985-08-05
DK147683C (da) 1985-05-13
RO69607A (ro) 1980-08-15
FI245674A (ja) 1975-02-22
CY945A (en) 1978-06-23
FR2241318A2 (ja) 1975-03-21
DE2439880A1 (de) 1975-04-03
AU473550B2 (en) 1976-06-24
IE39764L (en) 1975-02-21
KE2816A (en) 1978-02-24
RO64129A (fr) 1979-03-15
GT198302370A (es) 1984-11-20
FR2241318B2 (ja) 1979-08-10
AU7253174A (en) 1976-02-26
ATA676374A (de) 1977-03-15
PL115805B1 (en) 1981-05-30
DE2439880C3 (de) 1979-10-18
AR212156A1 (es) 1978-05-31
CS204989B2 (en) 1981-04-30
DK147683B (da) 1984-11-12
YU36737B (en) 1984-08-31
SU633483A3 (ru) 1978-11-15

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Legal Events

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