CH613975A5 - Process for the preparation of the syn isomer or of a mixture of syn isomer and anti isomer, where the content of the syn isomer is at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids with antibiotic activity - Google Patents

Process for the preparation of the syn isomer or of a mixture of syn isomer and anti isomer, where the content of the syn isomer is at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids with antibiotic activity

Info

Publication number
CH613975A5
CH613975A5 CH1135374A CH1135374A CH613975A5 CH 613975 A5 CH613975 A5 CH 613975A5 CH 1135374 A CH1135374 A CH 1135374A CH 1135374 A CH1135374 A CH 1135374A CH 613975 A5 CH613975 A5 CH 613975A5
Authority
CH
Switzerland
Prior art keywords
syn isomer
isomer
syn
acylaminoceph
mixture
Prior art date
Application number
CH1135374A
Inventor
Martin Christopher Cook
Gordon Ian Gregory
Janice Bradshaw
Original Assignee
Glaxo Operations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10410683&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH613975(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Operations Ltd filed Critical Glaxo Operations Ltd
Publication of CH613975A5 publication Critical patent/CH613975A5/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
CH1135374A 1973-08-21 1974-08-20 Process for the preparation of the syn isomer or of a mixture of syn isomer and anti isomer, where the content of the syn isomer is at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids with antibiotic activity CH613975A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3964573A GB1453049A (en) 1973-08-21 1973-08-21 Cephalosporing antibiotics

Publications (1)

Publication Number Publication Date
CH613975A5 true CH613975A5 (en) 1979-10-31

Family

ID=10410683

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1135374A CH613975A5 (en) 1973-08-21 1974-08-20 Process for the preparation of the syn isomer or of a mixture of syn isomer and anti isomer, where the content of the syn isomer is at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids with antibiotic activity
CH1013378A CH615931A5 (en) 1973-08-21 1978-09-28 Process for the preparation of the syn isomer or of a mixture of syn and anti isomers, the content of the syn isomer being at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1013378A CH615931A5 (en) 1973-08-21 1978-09-28 Process for the preparation of the syn isomer or of a mixture of syn and anti isomers, the content of the syn isomer being at least 90%, of 7-acylaminoceph-3-em-4-carboxylic acids

Country Status (32)

Country Link
JP (2) JPS562077B2 (en)
AR (2) AR212076A1 (en)
AT (1) AT340042B (en)
AU (1) AU473550B2 (en)
BE (1) BE819004R (en)
BG (2) BG25801A3 (en)
CA (1) CA1057283A (en)
CH (2) CH613975A5 (en)
CS (2) CS204989B2 (en)
CY (1) CY945A (en)
DD (1) DD114417A5 (en)
DE (2) DE2439880C3 (en)
DK (1) DK147683C (en)
ES (2) ES429388A1 (en)
FI (1) FI65623C (en)
FR (1) FR2241318B2 (en)
GB (1) GB1453049A (en)
GT (1) GT198302370A (en)
HK (1) HK17378A (en)
HU (1) HU170000B (en)
IE (1) IE39764B1 (en)
IL (1) IL45505A (en)
KE (1) KE2816A (en)
LU (2) LU70765A1 (en)
MY (1) MY7800188A (en)
NL (1) NL154741B (en)
NO (1) NO152751C (en)
PL (2) PL115805B1 (en)
RO (2) RO69607A (en)
SU (1) SU633483A3 (en)
YU (2) YU36737B (en)
ZA (1) ZA745331B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
FR2345153A1 (en) * 1976-03-25 1977-10-21 Roussel Uclaf NEW ALCOYLOXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
FI771866A (en) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
IT1162442B (en) * 1978-01-17 1987-04-01 Glaxo Group Ltd PROCEDURE FOR PREPARING THE CRYSTALLINE SHAPED SODIUM SALT OF CEFUROSSIMA
DE2804040C3 (en) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Process for the preparation of cephem compounds
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
IT1190734B (en) * 1982-03-11 1988-02-24 Opos Biochimica Srl PROCEDURE FOR THE PREPARATION OF CEFUROXIMA AND INTERMEDIATES USED IN SUCH PROCEDURE
GB8320520D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
WO2000053609A1 (en) * 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime
US20040191803A1 (en) * 2002-11-22 2004-09-30 Michela Gallagher Target for therapy of cognitive impairment
WO2004050663A2 (en) * 2002-12-05 2004-06-17 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefuroxime sodium
JP2008275173A (en) * 2008-08-04 2008-11-13 Toshiba Corp Branch pipe
EP2741750A1 (en) 2011-08-12 2014-06-18 Dhanuka Laboratories Ltd. Pharmaceutical composition comprising cefuroxime
WO2013038323A1 (en) 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
KR101497420B1 (en) 2013-07-05 2015-03-03 삼성중공업 주식회사 LNG transportation Apparatus for reducing Boil-Off Gas
CN105884799A (en) * 2015-09-23 2016-08-24 石药集团中诺药业(石家庄)有限公司 Novel cefuroxime sodium compound

Also Published As

Publication number Publication date
FI65623C (en) 1984-06-11
FI65623B (en) 1984-02-29
RO69607A (en) 1980-08-15
YU41231B (en) 1986-12-31
HK17378A (en) 1978-04-07
DE2462376A1 (en) 1976-11-25
YU30781A (en) 1983-02-28
GT198302370A (en) 1984-11-20
AU473550B2 (en) 1976-06-24
DE2439880C3 (en) 1979-10-18
JPS5649388A (en) 1981-05-02
DD114417A5 (en) 1975-08-05
SU633483A3 (en) 1978-11-15
NO742986L (en) 1975-03-17
IE39764B1 (en) 1978-12-20
JPS562077B2 (en) 1981-01-17
GB1453049A (en) 1976-10-20
AT340042B (en) 1977-11-25
ZA745331B (en) 1975-10-29
YU36737B (en) 1984-08-31
BG25801A3 (en) 1978-12-12
DK147683B (en) 1984-11-12
JPS5052083A (en) 1975-05-09
CA1057283A (en) 1979-06-26
CY945A (en) 1978-06-23
BG23903A3 (en) 1977-11-10
CH615931A5 (en) 1980-02-29
DK443274A (en) 1975-04-28
CS204989B2 (en) 1981-04-30
AR212156A1 (en) 1978-05-31
IL45505A (en) 1979-01-31
ES437269A1 (en) 1977-01-01
PL98962B1 (en) 1978-06-30
IE39764L (en) 1975-02-21
FR2241318B2 (en) 1979-08-10
ES429388A1 (en) 1976-08-16
DK147683C (en) 1985-05-13
NL7411095A (en) 1975-02-25
ATA676374A (en) 1977-03-15
NO152751C (en) 1985-11-13
YU228374A (en) 1982-06-18
NO152751B (en) 1985-08-05
DE2439880B2 (en) 1979-02-22
AU7253174A (en) 1976-02-26
CS204988B2 (en) 1981-04-30
NL154741B (en) 1977-10-17
AR212076A1 (en) 1978-05-15
IL45505A0 (en) 1974-11-29
LU70765A1 (en) 1975-12-09
FI245674A (en) 1975-02-22
LU88269I2 (en) 1994-02-03
DE2439880A1 (en) 1975-04-03
KE2816A (en) 1978-02-24
BE819004R (en) 1975-02-20
HU170000B (en) 1977-03-28
FR2241318A2 (en) 1975-03-21
MY7800188A (en) 1978-12-31
RO64129A (en) 1979-03-15
PL115805B1 (en) 1981-05-30

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