DE2265413C2 - 2,4-Diamino-5-(3,5-dimethoxy-4hydroxybenzyl)-6-methylthiopyrimidin - Google Patents

2,4-Diamino-5-(3,5-dimethoxy-4hydroxybenzyl)-6-methylthiopyrimidin

Info

Publication number
DE2265413C2
DE2265413C2 DE2265413A DE2265413A DE2265413C2 DE 2265413 C2 DE2265413 C2 DE 2265413C2 DE 2265413 A DE2265413 A DE 2265413A DE 2265413 A DE2265413 A DE 2265413A DE 2265413 C2 DE2265413 C2 DE 2265413C2
Authority
DE
Germany
Prior art keywords
diamino
dimethoxy
pyrimidine
methylthiopyrimidine
och
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2265413A
Other languages
German (de)
English (en)
Other versions
DE2265413B1 (de
Inventor
Barbara Chapel Hill N.C. Roth (V.St.A.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE2265413B1 publication Critical patent/DE2265413B1/de
Application granted granted Critical
Publication of DE2265413C2 publication Critical patent/DE2265413C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • H10W72/381—

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DE2265413A 1971-04-16 1972-04-14 2,4-Diamino-5-(3,5-dimethoxy-4hydroxybenzyl)-6-methylthiopyrimidin Expired DE2265413C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB964071A GB1401612A (en) 1971-04-16 1971-04-16 2,4-diamino-5-benzylpyrimidines and preparations thereof

Publications (2)

Publication Number Publication Date
DE2265413B1 DE2265413B1 (de) 1980-04-10
DE2265413C2 true DE2265413C2 (de) 1980-12-04

Family

ID=9875907

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2265413A Expired DE2265413C2 (de) 1971-04-16 1972-04-14 2,4-Diamino-5-(3,5-dimethoxy-4hydroxybenzyl)-6-methylthiopyrimidin
DE2218221A Expired DE2218221C3 (de) 1971-04-16 1972-04-14 Verfahren zur Herstellung von 2,4-Diamino-5-(3,43-trimethoxybenzyO-pyrimidin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2218221A Expired DE2218221C3 (de) 1971-04-16 1972-04-14 Verfahren zur Herstellung von 2,4-Diamino-5-(3,43-trimethoxybenzyO-pyrimidin

Country Status (25)

Country Link
US (1) US3822264A (enExample)
JP (1) JPS5324433B1 (enExample)
AR (1) AR193078A1 (enExample)
AT (1) AT316560B (enExample)
AU (1) AU468410B2 (enExample)
BE (1) BE782154R (enExample)
CA (1) CA978954A (enExample)
CH (1) CH565159A5 (enExample)
CS (2) CS178105B2 (enExample)
DD (1) DD97653A6 (enExample)
DE (2) DE2265413C2 (enExample)
DK (1) DK132221C (enExample)
ES (1) ES401796A2 (enExample)
FI (1) FI57400C (enExample)
FR (1) FR2133753B2 (enExample)
GB (1) GB1401612A (enExample)
HU (1) HU165865B (enExample)
IE (1) IE36289B1 (enExample)
IL (1) IL39221A (enExample)
NL (1) NL163214C (enExample)
NO (1) NO136046C (enExample)
PL (1) PL75399B3 (enExample)
SE (2) SE405118B (enExample)
ZA (1) ZA722533B (enExample)
ZM (1) ZM7072A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
US4039543A (en) * 1974-12-24 1977-08-02 Hoffmann-La Roche Inc. Benzylpyrimidines
DE2720771C3 (de) * 1977-05-09 1979-11-29 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-Diamino-5-(33-dimethoxy-4thioalkyl-benzyD-pyrimidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
JPS5888368A (ja) * 1981-11-09 1983-05-26 ザ・ウエルカム・フアウンデ−シヨン・リミテツド ベンジルピリミジン誘導体の製造法
DE3250132C2 (de) * 1981-11-09 1997-01-16 Mallinckrodt Veterinary Inc Verfahren zur Herstellung von 2,4-Diamino-5-benzyl-pyrimidinen und neue Zwischenprodukte des Verfahrens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR94837E (fr) * 1966-02-19 1969-11-28 Wellcome Found Procédé de préparation de dérivés de la pyrimidine.

Also Published As

Publication number Publication date
SE7503993L (enExample) 1975-04-08
IL39221A (en) 1975-11-25
HU165865B (enExample) 1974-11-28
CA978954A (en) 1975-12-02
IE36289B1 (en) 1976-09-29
IL39221A0 (en) 1972-06-28
FR2133753B2 (enExample) 1975-10-10
AT316560B (de) 1974-07-25
NO136046C (no) 1977-07-13
GB1401612A (en) 1975-07-16
JPS5324433B1 (enExample) 1978-07-20
BE782154R (fr) 1972-10-16
SE405118B (sv) 1978-11-20
US3822264A (en) 1974-07-02
ZA722533B (en) 1973-11-28
IE36289L (en) 1972-10-16
CS178105B2 (enExample) 1977-08-31
AU4117772A (en) 1973-10-18
FI57400B (fi) 1980-04-30
DK132221B (da) 1975-11-10
NL7205046A (enExample) 1972-10-18
NL163214B (nl) 1980-03-17
AR193078A1 (es) 1973-03-30
ES401796A2 (es) 1975-03-01
DE2218221B2 (de) 1978-05-24
PL75399B3 (en) 1974-12-31
DE2218221C3 (de) 1979-02-01
CS178140B2 (enExample) 1977-08-31
FI57400C (fi) 1980-08-11
NL163214C (nl) 1980-08-15
ZM7072A1 (en) 1974-03-21
DE2218221A1 (de) 1972-11-02
FR2133753A2 (enExample) 1972-12-01
CH565159A5 (enExample) 1975-08-15
DK132221C (da) 1976-04-20
SE417097B (sv) 1981-02-23
DD97653A6 (enExample) 1973-05-14
DE2265413B1 (de) 1980-04-10
NO136046B (enExample) 1977-04-04
AU468410B2 (en) 1973-10-18

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Legal Events

Date Code Title Description
OI Miscellaneous see part 1
OI Miscellaneous see part 1
OD Request for examination
OI Miscellaneous see part 1
8339 Ceased/non-payment of the annual fee