DE1595932C3 - Verfahren zur Herstellung von 1 (p Chlorbenzoyl) 5 methoxy 2 methylindol 3 essigsaure - Google Patents

Verfahren zur Herstellung von 1 (p Chlorbenzoyl) 5 methoxy 2 methylindol 3 essigsaure

Info

Publication number
DE1595932C3
DE1595932C3 DE1595932A DE1595932A DE1595932C3 DE 1595932 C3 DE1595932 C3 DE 1595932C3 DE 1595932 A DE1595932 A DE 1595932A DE 1595932 A DE1595932 A DE 1595932A DE 1595932 C3 DE1595932 C3 DE 1595932C3
Authority
DE
Germany
Prior art keywords
acetic acid
chlorobenzoyl
ester
methoxy
methylindole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1595932A
Other languages
German (de)
English (en)
Other versions
DE1595932B2 (de
DE1595932A1 (de
Inventor
George Summit Gal
Meyer North Plainfield Sletzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1595932A1 publication Critical patent/DE1595932A1/de
Publication of DE1595932B2 publication Critical patent/DE1595932B2/de
Application granted granted Critical
Publication of DE1595932C3 publication Critical patent/DE1595932C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE1595932A 1964-04-13 1965-04-13 Verfahren zur Herstellung von 1 (p Chlorbenzoyl) 5 methoxy 2 methylindol 3 essigsaure Expired DE1595932C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US359512A US3320280A (en) 1964-04-13 1964-04-13 Process for preparing alpha-(3-indolyl) lower aliphatic acids

Publications (3)

Publication Number Publication Date
DE1595932A1 DE1595932A1 (de) 1972-03-02
DE1595932B2 DE1595932B2 (de) 1973-04-26
DE1595932C3 true DE1595932C3 (de) 1973-11-22

Family

ID=23414137

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1595932A Expired DE1595932C3 (de) 1964-04-13 1965-04-13 Verfahren zur Herstellung von 1 (p Chlorbenzoyl) 5 methoxy 2 methylindol 3 essigsaure
DE19651770404 Pending DE1770404A1 (de) 1964-04-13 1965-04-13 Indolylessigsaeure-tert.-butylester und Verfahren zu ihrer Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19651770404 Pending DE1770404A1 (de) 1964-04-13 1965-04-13 Indolylessigsaeure-tert.-butylester und Verfahren zu ihrer Herstellung

Country Status (13)

Country Link
US (1) US3320280A (enExample)
BE (1) BE662404A (enExample)
BR (1) BR6568008D0 (enExample)
CH (2) CH468380A (enExample)
DE (2) DE1595932C3 (enExample)
DK (2) DK122280B (enExample)
ES (1) ES311977A1 (enExample)
FR (1) FR1590061A (enExample)
GB (1) GB1100602A (enExample)
IL (2) IL30709A (enExample)
NL (1) NL6504700A (enExample)
NO (1) NO123526B (enExample)
SE (3) SE332424B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3517020A (en) * 1967-11-01 1970-06-23 Sandoz Ag Certain 1-(3'-nicotinoyl)-2-loweralkylthio-benzimidazoles
US5245046A (en) * 1988-11-14 1993-09-14 The Upjohn Company α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2852531A (en) * 1954-09-24 1958-09-16 Merck & Co Inc Tris-(2-tetrahydropyranyl) esters of 6, 8-bis (hydrocarbonmercapto)-4, 4-dicarboxy-5-ocaprylic acid and preparation thereof
US3074942A (en) * 1958-01-13 1963-01-22 Geigy Chem Corp alpha-substituted glycine derivatives

Also Published As

Publication number Publication date
NO123526B (enExample) 1971-12-06
DE1595932B2 (de) 1973-04-26
CH467775A (de) 1969-01-31
CH468380A (de) 1969-02-15
ES311977A1 (es) 1965-11-16
SE332424B (enExample) 1971-02-08
GB1100602A (en) 1968-01-24
FR1590061A (enExample) 1970-04-13
BE662404A (enExample) 1965-10-12
DE1595932A1 (de) 1972-03-02
DK113778B (da) 1969-04-28
US3320280A (en) 1967-05-16
DK122280B (da) 1972-02-14
NL6504700A (enExample) 1965-10-14
BR6568008D0 (pt) 1973-08-07
SE332425B (enExample) 1971-02-08
DE1770404A1 (de) 1971-10-28
IL22995A (en) 1969-04-30
IL30709A (en) 1969-05-28
SE304993B (enExample) 1968-10-14

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977