DE1470029C3 - Verfahren zur Herstellung von Thiaxanthenderivaten - Google Patents

Verfahren zur Herstellung von Thiaxanthenderivaten

Info

Publication number
DE1470029C3
DE1470029C3 DE1470029A DE1470029A DE1470029C3 DE 1470029 C3 DE1470029 C3 DE 1470029C3 DE 1470029 A DE1470029 A DE 1470029A DE 1470029 A DE1470029 A DE 1470029A DE 1470029 C3 DE1470029 C3 DE 1470029C3
Authority
DE
Germany
Prior art keywords
radical
carbon atoms
methyl
mixture
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1470029A
Other languages
German (de)
English (en)
Other versions
DE1470029A1 (de
DE1470029B2 (de
Inventor
Edward Louis Gwynedd Valley Engelhardt
Ambler Zell Howard Charles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1470029A1 publication Critical patent/DE1470029A1/de
Publication of DE1470029B2 publication Critical patent/DE1470029B2/de
Application granted granted Critical
Publication of DE1470029C3 publication Critical patent/DE1470029C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fertilizers (AREA)
DE1470029A 1961-09-29 1962-09-12 Verfahren zur Herstellung von Thiaxanthenderivaten Expired DE1470029C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US141607A US3275640A (en) 1961-09-29 1961-09-29 Substituted 1-hydrocarbyl-4-(10-thiaxanthylidene) piperidines

Publications (3)

Publication Number Publication Date
DE1470029A1 DE1470029A1 (de) 1969-04-30
DE1470029B2 DE1470029B2 (de) 1974-06-06
DE1470029C3 true DE1470029C3 (de) 1975-02-20

Family

ID=22496410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1470029A Expired DE1470029C3 (de) 1961-09-29 1962-09-12 Verfahren zur Herstellung von Thiaxanthenderivaten

Country Status (13)

Country Link
US (1) US3275640A (enExample)
BE (1) BE622809A (enExample)
BR (1) BR6243360D0 (enExample)
CH (1) CH429724A (enExample)
DE (1) DE1470029C3 (enExample)
DK (1) DK120490B (enExample)
ES (1) ES281419A1 (enExample)
FI (1) FI43983B (enExample)
FR (2) FR1501704A (enExample)
GB (1) GB1015793A (enExample)
NL (2) NL283292A (enExample)
NO (1) NO115109B (enExample)
SE (1) SE333928B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301204A (enExample) * 1962-12-07
US3464983A (en) * 1964-02-04 1969-09-02 Sandoz Ag 4h-benzo(4,5)cyclohepta(1,2-b)thiophenes
US3470188A (en) * 1967-01-05 1969-09-30 Smithkline Corp 9-cycloalkyl-lower alkyl-piperidylidene derivatives of xanthenes and thioxanthenes
USB426802I5 (enExample) * 1972-11-20 1976-02-17
GB1434486A (en) * 1974-02-04 1976-05-05 Ici Ltd Thioxanthene derivatives
US4086350A (en) * 1974-11-06 1978-04-25 Smithkline Corporation Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms
ZA756550B (en) * 1974-11-06 1976-09-29 Smithkline Corp Pharmaceutical compositions and method of producing antipsychotic activity without extrapyramidal symptoms
US4076714A (en) * 1974-11-25 1978-02-28 Merck & Co., Inc. 1-Methyl-4-(2-carboxy-thioxanthen-9-ylidene)-piperidine an appetite stimulant and antihistaminic agent
US4021561A (en) * 1975-12-22 1977-05-03 Merck & Co., Inc. Trifluoromethylthio- and trifluoromethylsulfonyl-thioxanthen-9-ylidenepiperidines
US4073912A (en) * 1976-10-12 1978-02-14 Smithkline Corporation Piperidylidene derivatives of benzo-fused xanthenes, thioxanthenes and dibenzoxepins and antipsychotic use thereof
US4169205A (en) * 1978-10-25 1979-09-25 E. R. Squibb & Sons, Inc. Imidazole derivatives of 6,11-dihydrodibenz[b,e]oxepines and 6,11-dihydrodibenz[b,e]thiepines
DE3160719D1 (en) * 1980-03-06 1983-09-08 Roussel Uclaf Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them
US4777177A (en) * 1984-10-19 1988-10-11 Ciba-Geigy Corporation Pesticidal thioxanthen-9-ylidenepiperidines
EP1270568A1 (en) * 2001-06-19 2003-01-02 Biofrontera Pharmaceuticals AG 1-methyl-4-(3-ethoxy-9h-thioxanthene-ylidene)-piperidine and its use as 5-HT2B and/or H1 antagonist
US7060711B2 (en) * 2001-10-25 2006-06-13 Biofrontera Bioscience Gmbh Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist
EP1306376A1 (en) * 2001-10-25 2003-05-02 Biofrontera Pharmaceuticals AG Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist
WO2014117863A1 (en) 2013-02-01 2014-08-07 Biofrontera Bioscience Gmbh Salt polymorph of thioxanthene - 9 - ylidene - 1 - methyl piperidine acid addition salts as antimigraine compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996503A (en) * 1955-09-23 1961-08-15 Merck & Co Inc Derivatives of heterocyclic compounds
GB829763A (en) * 1955-09-23 1960-03-09 Merck & Co Inc Derivatives of thiaxanthene
BE557002A (enExample) * 1956-07-09
BE568611A (enExample) * 1957-07-18
US3014911A (en) * 1958-09-29 1961-12-26 Merck & Co Inc Derivatives of dibenzo[a, e]cycloheptatriene
BE585338A (enExample) * 1958-12-04
US3073847A (en) * 1959-02-12 1963-01-15 Hoffmann La Roche 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation
NL260070A (enExample) * 1960-02-25

Also Published As

Publication number Publication date
DE1470029A1 (de) 1969-04-30
BE622809A (fr) 1963-03-25
FR1501704A (fr) 1967-11-18
FI43983B (enExample) 1971-04-30
NL122808C (enExample)
BR6243360D0 (pt) 1973-05-24
ES281419A1 (es) 1963-02-01
NL283292A (enExample)
CH429724A (de) 1967-02-15
SE333928B (enExample) 1971-04-05
DE1470029B2 (de) 1974-06-06
US3275640A (en) 1966-09-27
NO115109B (enExample) 1968-07-29
FR2959M (fr) 1964-11-30
GB1015793A (en) 1966-01-05
DK120490B (da) 1971-06-07

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Legal Events

Date Code Title Description
SH Request for examination between 03.10.1968 and 22.04.1971
C3 Grant after two publication steps (3rd publication)