DD279013A5 - Verfahren zum herstellen von sertralin-zwischenverbindungen - Google Patents

Verfahren zum herstellen von sertralin-zwischenverbindungen Download PDF

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Publication number
DD279013A5
DD279013A5 DD88325879A DD32587988A DD279013A5 DD 279013 A5 DD279013 A5 DD 279013A5 DD 88325879 A DD88325879 A DD 88325879A DD 32587988 A DD32587988 A DD 32587988A DD 279013 A5 DD279013 A5 DD 279013A5
Authority
DD
German Democratic Republic
Prior art keywords
dichlorophenyl
acid
dihydro
benzene
furanone
Prior art date
Application number
DD88325879A
Other languages
German (de)
English (en)
Inventor
George J Quallich
Michael T Williams
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD279013A5 publication Critical patent/DD279013A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/15Saturated compounds containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Catalysts (AREA)
DD88325879A 1987-06-11 1988-06-10 Verfahren zum herstellen von sertralin-zwischenverbindungen DD279013A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/060,577 US4777288A (en) 1987-06-11 1987-06-11 Process for preparing a 4,4-diphenylbutanoic acid derivative

Publications (1)

Publication Number Publication Date
DD279013A5 true DD279013A5 (de) 1990-05-23

Family

ID=22030394

Family Applications (2)

Application Number Title Priority Date Filing Date
DD88325879A DD279013A5 (de) 1987-06-11 1988-06-10 Verfahren zum herstellen von sertralin-zwischenverbindungen
DD88316663A DD287483A5 (de) 1987-06-11 1988-06-10 Verfahren zum herstellen von 4-(3,4-dichlorphenyl)-4-phenylbuttersaeure als sertralin-zwischenverbindung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD88316663A DD287483A5 (de) 1987-06-11 1988-06-10 Verfahren zum herstellen von 4-(3,4-dichlorphenyl)-4-phenylbuttersaeure als sertralin-zwischenverbindung

Country Status (29)

Country Link
US (1) US4777288A (fi)
EP (1) EP0295050B1 (fi)
JP (1) JPH0627098B2 (fi)
KR (1) KR910000780B1 (fi)
CN (2) CN1025328C (fi)
AT (1) ATE62657T1 (fi)
AU (1) AU586953B2 (fi)
CA (1) CA1285574C (fi)
CS (1) CS272238B2 (fi)
DD (2) DD279013A5 (fi)
DE (1) DE3862434D1 (fi)
DK (1) DK175280B1 (fi)
EG (1) EG18404A (fi)
ES (1) ES2022621B3 (fi)
FI (1) FI90657C (fi)
GR (1) GR3001908T3 (fi)
HU (2) HU213617B (fi)
IE (1) IE61072B1 (fi)
IL (1) IL86629A0 (fi)
MX (1) MX172786B (fi)
MY (2) MY103570A (fi)
NO (1) NO167731C (fi)
NZ (1) NZ224984A (fi)
PH (1) PH25099A (fi)
PL (2) PL153028B1 (fi)
PT (1) PT87691B (fi)
RU (2) RU1799377C (fi)
YU (2) YU47120B (fi)
ZA (1) ZA884161B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE145198T1 (de) * 1991-12-13 1996-11-15 Pfizer Verfahren zur herstellung eines keton enantiomers
US5196607A (en) * 1992-02-14 1993-03-23 Pfizer Inc. Process for preparing ketone enantiomer
US5466880A (en) * 1992-09-15 1995-11-14 Pfizer Inc. Process for preparing ketone enantiomer
DK0724552T3 (da) * 1993-11-30 1997-12-22 Pfizer Fremgangsmåde til fremstilling af chiralt tetralon
US6410794B1 (en) 1994-12-16 2002-06-25 Uop Llc Process for preparation of pharmaceutically desired chiral tetralone from tetralones
IL152330A0 (en) 1997-07-01 2003-05-29 Pfizer Sertraline salts and sustained-release dosage forms of sertraline
WO1999046233A1 (fr) * 1998-03-09 1999-09-16 Sumika Fine Chemicals Co., Ltd. Derives de l'alcool benzylique
IL132500A0 (en) 1998-10-29 2001-03-19 Pfizer Prod Inc Stereoselective microbial reduction of a racemic tetralone
IN187170B (fi) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
FR2817256B1 (fr) * 2000-11-27 2005-07-15 Univ Pasteur Derives de l'acides 4-hydroxybutanoique et de son homologue superieur comme ligands des recepteurs du gamma- hydroxybutyrate (ghb), compositions pharmaceutiques les contenant et utilisations pharmaceutiques
CN100413856C (zh) * 2006-09-06 2008-08-27 大连来克精化有限公司 一种威士忌内酯的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3412146A (en) * 1965-08-13 1968-11-19 Geigy Chem Corp Process for preparation of diphenyl alkanoic acids
DE2112715A1 (de) * 1971-03-17 1972-10-05 Thomae Gmbh Dr K Neue 4-(4-Biphenylyl)-4-hydroxybuttersaeuren,ihre Salze,Ester und Lactone
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4556676A (en) * 1979-11-01 1985-12-03 Pfizer Inc. Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
FR2504127B1 (fr) * 1981-04-17 1985-07-19 Roussel Uclaf Nouveaux derives d'acides phenyl aliphatique carboxyliques, procede pour leur preparation et leur application comme medicaments
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee
US4543428A (en) * 1983-03-11 1985-09-24 Oregon Graduate Center For Study & Research Production of a hexahydronaphthalenone compound
DE3615157A1 (de) * 1986-05-05 1987-11-12 Schwabe Willmar Gmbh & Co 5-arylalkyl-4-alkoxy-2(5h)-furanone, zwischenprodukte und verfahren zu ihrer herstellung sowie ihre anwendung als therapeutische wirkstoffe
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine

Also Published As

Publication number Publication date
NO882566D0 (no) 1988-06-10
NZ224984A (en) 1990-04-26
IE61072B1 (en) 1994-09-21
HUT47070A (en) 1989-01-30
HU198670B (en) 1989-11-28
PT87691A (pt) 1988-07-01
KR890000393A (ko) 1989-03-14
DD287483A5 (de) 1991-02-28
EP0295050A1 (en) 1988-12-14
FI882779A0 (fi) 1988-06-10
IL86629A0 (en) 1988-11-30
RU1839670C (ru) 1993-12-30
EP0295050B1 (en) 1991-04-17
ATE62657T1 (de) 1991-05-15
JPH0627098B2 (ja) 1994-04-13
PT87691B (pt) 1992-09-30
PL153028B1 (en) 1991-02-28
DK319088D0 (da) 1988-06-10
DK175280B1 (da) 2004-08-09
PH25099A (en) 1991-02-19
CN1100086A (zh) 1995-03-15
MX11861A (es) 1993-03-01
MY107026A (en) 1995-08-30
DE3862434D1 (de) 1991-05-23
FI90657B (fi) 1993-11-30
AU586953B2 (en) 1989-07-27
IE881762L (en) 1988-12-11
ES2022621B3 (es) 1991-12-01
DK319088A (da) 1988-12-12
FI90657C (fi) 1994-03-10
CS397688A2 (en) 1990-03-14
FI882779A (fi) 1988-12-12
RU1799377C (ru) 1993-02-28
HU213617B (en) 1997-08-28
CN1042129C (zh) 1999-02-17
YU47120B (sh) 1994-12-28
PL272949A1 (en) 1989-07-10
NO167731B (no) 1991-08-26
YU60893A (sh) 1997-05-28
CN1025328C (zh) 1994-07-06
ZA884161B (en) 1990-02-28
YU49242B (sh) 2004-12-31
EG18404A (en) 1993-02-28
GR3001908T3 (en) 1992-11-23
JPS649953A (en) 1989-01-13
CS272238B2 (en) 1991-01-15
NO167731C (no) 1992-03-04
KR910000780B1 (ko) 1991-02-08
CA1285574C (en) 1991-07-02
PL156829B1 (pl) 1992-04-30
YU112788A (en) 1989-10-31
AU1761388A (en) 1988-12-15
CN1031837A (zh) 1989-03-22
PL278118A1 (en) 1989-08-21
MX172786B (es) 1994-01-13
US4777288A (en) 1988-10-11
MY103570A (en) 1993-08-28
NO882566L (no) 1988-12-12

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Legal Events

Date Code Title Description
NPV Change in the person, the name or the address of the representative (addendum to changes before extension act)
ENJ Ceased due to non-payment of renewal fee