DD244977A5 - Verfahren zur herstellung von neuen 7-oxo-pgi tief 2-ephedrin-salz-analogen - Google Patents

Verfahren zur herstellung von neuen 7-oxo-pgi tief 2-ephedrin-salz-analogen Download PDF

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Publication number
DD244977A5
DD244977A5 DD86290679A DD29067986A DD244977A5 DD 244977 A5 DD244977 A5 DD 244977A5 DD 86290679 A DD86290679 A DD 86290679A DD 29067986 A DD29067986 A DD 29067986A DD 244977 A5 DD244977 A5 DD 244977A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
oxo
hydrogen
compound
ephedrine
Prior art date
Application number
DD86290679A
Other languages
German (de)
English (en)
Inventor
Gabor Kovacs
Geza Galambos
Istvan Toemoeskoezi
Karoly Kanai
Peter Gyoery
Peter Koermoeczy
Istvan Stadler
Laszlo Szekeres
Gyula Papp
Eva Udvary
Pal Hadhazy
Jenoe Marton
Gyoergy Dorman
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@���������@��@����������@��������@�����@��Kk�� filed Critical �������@���������@��@����������@��������@�����@��Kk��
Publication of DD244977A5 publication Critical patent/DD244977A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD86290679A 1985-05-29 1986-05-28 Verfahren zur herstellung von neuen 7-oxo-pgi tief 2-ephedrin-salz-analogen DD244977A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852050A HU197733B (en) 1985-05-29 1985-05-29 Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives

Publications (1)

Publication Number Publication Date
DD244977A5 true DD244977A5 (de) 1987-04-22

Family

ID=10957509

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86290679A DD244977A5 (de) 1985-05-29 1986-05-28 Verfahren zur herstellung von neuen 7-oxo-pgi tief 2-ephedrin-salz-analogen

Country Status (23)

Country Link
US (1) US4735965A (sv)
EP (1) EP0205969B1 (sv)
JP (1) JPS61277650A (sv)
KR (1) KR860009031A (sv)
CN (1) CN1010587B (sv)
AT (1) ATE71093T1 (sv)
AU (1) AU588761B2 (sv)
CS (1) CS261894B2 (sv)
DD (1) DD244977A5 (sv)
DE (1) DE3683192D1 (sv)
DK (1) DK249686A (sv)
ES (1) ES8706624A1 (sv)
FI (1) FI82690C (sv)
GR (1) GR861390B (sv)
HU (1) HU197733B (sv)
IL (1) IL78849A (sv)
NO (1) NO171677C (sv)
NZ (1) NZ216339A (sv)
PL (1) PL148718B1 (sv)
PT (1) PT82657B (sv)
SU (2) SU1454250A3 (sv)
YU (1) YU46169B (sv)
ZA (1) ZA863801B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729153D0 (en) * 1987-12-14 1988-01-27 Efamol Ltd Fatty acid compositions
HU227157B1 (en) * 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU502731B2 (en) * 1975-09-17 1979-08-09 The Upjohn Company Prostaglandin analogues
IT1088036B (it) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
HU182012B (en) * 1979-11-12 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6-substituted-7-oxo-pgi down 1 derivatives
US4330553A (en) * 1979-11-12 1982-05-18 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same
DE3035454A1 (de) * 1980-09-18 1982-04-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung
HU191264B (en) * 1984-01-13 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect

Also Published As

Publication number Publication date
GR861390B (en) 1986-09-17
PT82657A (en) 1986-06-01
US4735965A (en) 1988-04-05
JPS61277650A (ja) 1986-12-08
CN86103741A (zh) 1987-02-18
DE3683192D1 (de) 1992-02-13
DK249686D0 (da) 1986-05-28
IL78849A0 (en) 1986-09-30
FI82690B (fi) 1990-12-31
HUT40635A (en) 1987-01-28
IL78849A (en) 1990-01-18
CN1010587B (zh) 1990-11-28
NO171677C (no) 1993-04-21
FI862159A0 (fi) 1986-05-22
HU197733B (en) 1989-05-29
NO862112L (no) 1986-12-01
SU1454250A3 (ru) 1989-01-23
ZA863801B (en) 1987-01-28
NZ216339A (en) 1989-08-29
DK249686A (da) 1986-11-30
FI862159A (fi) 1986-11-30
ATE71093T1 (de) 1992-01-15
AU588761B2 (en) 1989-09-21
FI82690C (sv) 1991-04-10
PL148718B1 (en) 1989-11-30
ES8706624A1 (es) 1987-07-01
SU1447823A1 (ru) 1988-12-30
AU5800186A (en) 1986-12-04
EP0205969B1 (de) 1992-01-02
NO171677B (no) 1993-01-11
ES555454A0 (es) 1987-07-01
CS261894B2 (en) 1989-02-10
YU46169B (sh) 1993-05-28
KR860009031A (ko) 1986-12-19
EP0205969A2 (de) 1986-12-30
PT82657B (pt) 1988-03-03
EP0205969A3 (en) 1989-04-19
YU90986A (en) 1988-02-29

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