DE69018741T2 - Konjugierte gamma-Hydroxybutenolid-Derivate und sie als aktiver Wirkstoff enthaltende Mittel gegen Magengeschwüre. - Google Patents

Konjugierte gamma-Hydroxybutenolid-Derivate und sie als aktiver Wirkstoff enthaltende Mittel gegen Magengeschwüre.

Info

Publication number
DE69018741T2
DE69018741T2 DE69018741T DE69018741T DE69018741T2 DE 69018741 T2 DE69018741 T2 DE 69018741T2 DE 69018741 T DE69018741 T DE 69018741T DE 69018741 T DE69018741 T DE 69018741T DE 69018741 T2 DE69018741 T2 DE 69018741T2
Authority
DE
Germany
Prior art keywords
hydroxybutenolide
group
derivatives
active ingredients
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69018741T
Other languages
English (en)
Other versions
DE69018741D1 (de
Inventor
Yoshin Tamai
Masahiro Torihara
Yoichi Kido
Johji Yamahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Application granted granted Critical
Publication of DE69018741D1 publication Critical patent/DE69018741D1/de
Publication of DE69018741T2 publication Critical patent/DE69018741T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69018741T 1989-09-20 1990-09-05 Konjugierte gamma-Hydroxybutenolid-Derivate und sie als aktiver Wirkstoff enthaltende Mittel gegen Magengeschwüre. Expired - Fee Related DE69018741T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1245754A JP2790335B2 (ja) 1989-09-20 1989-09-20 共役γ―オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤

Publications (2)

Publication Number Publication Date
DE69018741D1 DE69018741D1 (de) 1995-05-24
DE69018741T2 true DE69018741T2 (de) 1995-10-12

Family

ID=17138301

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69018741T Expired - Fee Related DE69018741T2 (de) 1989-09-20 1990-09-05 Konjugierte gamma-Hydroxybutenolid-Derivate und sie als aktiver Wirkstoff enthaltende Mittel gegen Magengeschwüre.

Country Status (5)

Country Link
US (1) US5084464A (de)
EP (1) EP0418655B1 (de)
JP (1) JP2790335B2 (de)
AT (1) ATE121394T1 (de)
DE (1) DE69018741T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3938468A1 (de) * 1989-11-18 1991-05-23 Basf Ag 1,1-dialkoxy-2-oxo-6-aryl-3,5-alkadiene
US5508302A (en) * 1994-09-28 1996-04-16 American Home Products Corporation Phospholipase A2 inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5916884A (ja) * 1982-07-19 1984-01-28 Fujisawa Pharmaceut Co Ltd 新規フラン化合物
US4789749A (en) * 1984-06-18 1988-12-06 The Regents Of The University Of California Manoalide analogs
JPS61212578A (ja) * 1985-03-15 1986-09-20 Nippon Soda Co Ltd ２−フラノン誘導体及びその製造方法
ZA864674B (en) * 1985-07-01 1988-02-24 Lilly Co Eli Furanone derivatives
JPH0222271A (ja) * 1988-07-11 1990-01-25 Kuraray Co Ltd 共役γ−オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤
JPH0676067B2 (ja) * 1988-12-17 1994-09-28 三菱自動車エンジニアリング株式会社 トラックの車台フレーム

Also Published As

Publication number Publication date
EP0418655A3 (en) 1991-12-18
US5084464A (en) 1992-01-28
JP2790335B2 (ja) 1998-08-27
JPH03106870A (ja) 1991-05-07
ATE121394T1 (de) 1995-05-15
EP0418655A2 (de) 1991-03-27
EP0418655B1 (de) 1995-04-19
DE69018741D1 (de) 1995-05-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee