NO171677C - Fremgangsmaate ved fremstilling av krystallinske 7-oxo-pgi2-efedrinsaltanaloger - Google Patents

Fremgangsmaate ved fremstilling av krystallinske 7-oxo-pgi2-efedrinsaltanaloger

Info

Publication number
NO171677C
NO171677C NO862112A NO862112A NO171677C NO 171677 C NO171677 C NO 171677C NO 862112 A NO862112 A NO 862112A NO 862112 A NO862112 A NO 862112A NO 171677 C NO171677 C NO 171677C
Authority
NO
Norway
Prior art keywords
pgi2
stands
prevention
hydrogen
lower alkyl
Prior art date
Application number
NO862112A
Other languages
English (en)
Norwegian (no)
Other versions
NO862112L (no
NO171677B (no
Inventor
Gabor Kovacs
Geza Galambos
Istvan Toemoeskoezi
Karoly Kanai
Peter Gyoery
Peter Koermoeczy
Istvan Stadler
Pal Hadhazy
Jenoe Marton
Gyoeegy Dorman
Laszlo Szekeres
Gyula Papp
Eva Udvary
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of NO862112L publication Critical patent/NO862112L/no
Publication of NO171677B publication Critical patent/NO171677B/no
Publication of NO171677C publication Critical patent/NO171677C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO862112A 1985-05-29 1986-05-28 Fremgangsmaate ved fremstilling av krystallinske 7-oxo-pgi2-efedrinsaltanaloger NO171677C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852050A HU197733B (en) 1985-05-29 1985-05-29 Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives

Publications (3)

Publication Number Publication Date
NO862112L NO862112L (no) 1986-12-01
NO171677B NO171677B (no) 1993-01-11
NO171677C true NO171677C (no) 1993-04-21

Family

ID=10957509

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862112A NO171677C (no) 1985-05-29 1986-05-28 Fremgangsmaate ved fremstilling av krystallinske 7-oxo-pgi2-efedrinsaltanaloger

Country Status (23)

Country Link
US (1) US4735965A (sv)
EP (1) EP0205969B1 (sv)
JP (1) JPS61277650A (sv)
KR (1) KR860009031A (sv)
CN (1) CN1010587B (sv)
AT (1) ATE71093T1 (sv)
AU (1) AU588761B2 (sv)
CS (1) CS261894B2 (sv)
DD (1) DD244977A5 (sv)
DE (1) DE3683192D1 (sv)
DK (1) DK249686A (sv)
ES (1) ES8706624A1 (sv)
FI (1) FI82690C (sv)
GR (1) GR861390B (sv)
HU (1) HU197733B (sv)
IL (1) IL78849A (sv)
NO (1) NO171677C (sv)
NZ (1) NZ216339A (sv)
PL (1) PL148718B1 (sv)
PT (1) PT82657B (sv)
SU (2) SU1454250A3 (sv)
YU (1) YU46169B (sv)
ZA (1) ZA863801B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729153D0 (en) * 1987-12-14 1988-01-27 Efamol Ltd Fatty acid compositions
HU227157B1 (en) * 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU502731B2 (en) * 1975-09-17 1979-08-09 The Upjohn Company Prostaglandin analogues
IT1088036B (it) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
HU182012B (en) * 1979-11-12 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6-substituted-7-oxo-pgi down 1 derivatives
US4330553A (en) * 1979-11-12 1982-05-18 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same
DE3035454A1 (de) * 1980-09-18 1982-04-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung
HU191264B (en) * 1984-01-13 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect

Also Published As

Publication number Publication date
GR861390B (en) 1986-09-17
PT82657A (en) 1986-06-01
US4735965A (en) 1988-04-05
JPS61277650A (ja) 1986-12-08
CN86103741A (zh) 1987-02-18
DE3683192D1 (de) 1992-02-13
DK249686D0 (da) 1986-05-28
IL78849A0 (en) 1986-09-30
FI82690B (fi) 1990-12-31
HUT40635A (en) 1987-01-28
DD244977A5 (de) 1987-04-22
IL78849A (en) 1990-01-18
CN1010587B (zh) 1990-11-28
FI862159A0 (fi) 1986-05-22
HU197733B (en) 1989-05-29
NO862112L (no) 1986-12-01
SU1454250A3 (ru) 1989-01-23
ZA863801B (en) 1987-01-28
NZ216339A (en) 1989-08-29
DK249686A (da) 1986-11-30
FI862159A (fi) 1986-11-30
ATE71093T1 (de) 1992-01-15
AU588761B2 (en) 1989-09-21
FI82690C (sv) 1991-04-10
PL148718B1 (en) 1989-11-30
ES8706624A1 (es) 1987-07-01
SU1447823A1 (ru) 1988-12-30
AU5800186A (en) 1986-12-04
EP0205969B1 (de) 1992-01-02
NO171677B (no) 1993-01-11
ES555454A0 (es) 1987-07-01
CS261894B2 (en) 1989-02-10
YU46169B (sh) 1993-05-28
KR860009031A (ko) 1986-12-19
EP0205969A2 (de) 1986-12-30
PT82657B (pt) 1988-03-03
EP0205969A3 (en) 1989-04-19
YU90986A (en) 1988-02-29

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