FR2449680A1 - Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant - Google Patents
Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenantInfo
- Publication number
- FR2449680A1 FR2449680A1 FR8003580A FR8003580A FR2449680A1 FR 2449680 A1 FR2449680 A1 FR 2449680A1 FR 8003580 A FR8003580 A FR 8003580A FR 8003580 A FR8003580 A FR 8003580A FR 2449680 A1 FR2449680 A1 FR 2449680A1
- Authority
- FR
- France
- Prior art keywords
- alcoyl
- hydroyl
- prostaglandin
- analogs
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003174 prostaglandin I2 derivatives Chemical class 0.000 title 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical compound C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical class C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
L'INVENTION CONCERNE DES ANALOGUES DE LA PROSTAGLANDINE I. CES COMPOSES ONT LA FORMULE CI-DESSOUS, DANS LAQUELLE R H, ALCOYLE, ARALCOYLE, CYCLOALCOYLE OU PHENYL SUBSTITUES OU NON, OU GROUPE ALCOXYCARBONYLALCOYLE, HYDROXYALCOYLE, ALCOXYALCOYLE OU AMINO-ALCOYLE, R H, METHYLE OU ETHYL, R ALCOYLE, R H OU ALCOYLE, R ALCOYLE, ET Y ETHYLENE OU VINYLENE TRANS. APPLICATIONS PHARMACOLOGIQUES, EN PARTICULIER POUR TRAITER LES MALADIES CARDIOVASCULAIRES ET LES ULCERES GASTRIQUES. (CF DESSIN DANS BOPI)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1793579A JPS55111465A (en) | 1979-02-20 | 1979-02-20 | Prostaglandin i2 analog and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2449680A1 true FR2449680A1 (fr) | 1980-09-19 |
| FR2449680B1 FR2449680B1 (fr) | 1983-04-15 |
Family
ID=11957625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8003580A Granted FR2449680A1 (fr) | 1979-02-20 | 1980-02-19 | Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4313954A (fr) |
| JP (1) | JPS55111465A (fr) |
| AU (1) | AU540973B2 (fr) |
| BE (1) | BE881799A (fr) |
| CA (1) | CA1154442A (fr) |
| CH (1) | CH646152A5 (fr) |
| DE (1) | DE3006032A1 (fr) |
| FR (1) | FR2449680A1 (fr) |
| GB (1) | GB2044763B (fr) |
| HU (1) | HU184239B (fr) |
| IE (1) | IE49512B1 (fr) |
| IT (1) | IT1141221B (fr) |
| LU (1) | LU82182A1 (fr) |
| NL (1) | NL8000987A (fr) |
| ZA (1) | ZA80921B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
| JPS6130519A (ja) * | 1984-07-23 | 1986-02-12 | Dainippon Pharmaceut Co Ltd | 脳神経細胞の酸素欠乏性疾患治療剤 |
| DE102014200866A1 (de) * | 2014-01-17 | 2015-07-23 | Iwa - F. Riehle Gmbh & Co Kg | Vorrichtung zur Ermittlung einer zu spritzenden Insulinmenge bei Diabetes-Patienten |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4097489A (en) * | 1977-06-17 | 1978-06-27 | The Upjohn Company | 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds |
| JPS54125653A (en) * | 1978-03-18 | 1979-09-29 | Ono Pharmaceut Co Ltd | Prostaglandin i2 analog, its preparation, and drug composition comprising it as active constituent |
| US4211706A (en) * | 1978-10-13 | 1980-07-08 | The Upjohn Company | 9-Deoxy-9α,6-nitrilo or 6,9α-imino-17,18-didehydro-PGF compounds |
-
1979
- 1979-02-20 JP JP1793579A patent/JPS55111465A/ja active Granted
-
1980
- 1980-02-18 AU AU55625/80A patent/AU540973B2/en not_active Ceased
- 1980-02-18 NL NL8000987A patent/NL8000987A/nl not_active Application Discontinuation
- 1980-02-18 DE DE19803006032 patent/DE3006032A1/de active Granted
- 1980-02-18 ZA ZA00800921A patent/ZA80921B/xx unknown
- 1980-02-18 IE IE297/80A patent/IE49512B1/en unknown
- 1980-02-18 CA CA000345900A patent/CA1154442A/fr not_active Expired
- 1980-02-18 HU HU80368A patent/HU184239B/hu not_active IP Right Cessation
- 1980-02-18 GB GB8005439A patent/GB2044763B/en not_active Expired
- 1980-02-18 IT IT19983/80A patent/IT1141221B/it active
- 1980-02-19 LU LU82182A patent/LU82182A1/fr unknown
- 1980-02-19 FR FR8003580A patent/FR2449680A1/fr active Granted
- 1980-02-19 CH CH133580A patent/CH646152A5/fr not_active IP Right Cessation
- 1980-02-19 US US06/122,704 patent/US4313954A/en not_active Expired - Lifetime
- 1980-02-19 BE BE0/199455A patent/BE881799A/fr not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| EXBK/78 * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2449680B1 (fr) | 1983-04-15 |
| JPS6228134B2 (fr) | 1987-06-18 |
| LU82182A1 (fr) | 1980-09-24 |
| CH646152A5 (fr) | 1984-11-15 |
| NL8000987A (nl) | 1980-08-22 |
| CA1154442A (fr) | 1983-09-27 |
| US4313954A (en) | 1982-02-02 |
| DE3006032C2 (fr) | 1988-03-17 |
| ZA80921B (en) | 1981-02-25 |
| IE800297L (en) | 1980-08-20 |
| GB2044763B (en) | 1983-02-23 |
| AU540973B2 (en) | 1984-12-13 |
| IT1141221B (it) | 1986-10-01 |
| DE3006032A1 (de) | 1980-08-28 |
| IT8019983A0 (it) | 1980-02-18 |
| GB2044763A (en) | 1980-10-22 |
| HU184239B (en) | 1984-07-30 |
| AU5562580A (en) | 1980-08-28 |
| BE881799A (fr) | 1980-08-19 |
| IE49512B1 (en) | 1985-10-16 |
| JPS55111465A (en) | 1980-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |