DD211565A5 - Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel - Google Patents

Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel Download PDF

Info

Publication number
DD211565A5
DD211565A5 DD83248328A DD24832883A DD211565A5 DD 211565 A5 DD211565 A5 DD 211565A5 DD 83248328 A DD83248328 A DD 83248328A DD 24832883 A DD24832883 A DD 24832883A DD 211565 A5 DD211565 A5 DD 211565A5
Authority
DD
German Democratic Republic
Prior art keywords
erythromycin
epi
product
reaction
water
Prior art date
Application number
DD83248328A
Other languages
German (de)
English (en)
Inventor
Frank Ch Sciavolino
Mark A Guadliana
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD211565A5 publication Critical patent/DD211565A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
DD83248328A 1982-03-01 1983-02-28 Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel DD211565A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/353,547 US4382085A (en) 1982-03-01 1982-03-01 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents

Publications (1)

Publication Number Publication Date
DD211565A5 true DD211565A5 (de) 1984-07-18

Family

ID=23389603

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83248328A DD211565A5 (de) 1982-03-01 1983-02-28 Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel

Country Status (26)

Country Link
US (1) US4382085A (cs)
EP (1) EP0087905B1 (cs)
JP (1) JPS58159499A (cs)
KR (1) KR850000965B1 (cs)
AT (1) ATE15048T1 (cs)
AU (1) AU555208B2 (cs)
CA (1) CA1178596A (cs)
CS (3) CS235036B2 (cs)
DD (1) DD211565A5 (cs)
DE (1) DE3360589D1 (cs)
DK (1) DK157495C (cs)
EG (1) EG16630A (cs)
ES (2) ES520177A0 (cs)
FI (1) FI74287C (cs)
GR (1) GR78094B (cs)
GT (1) GT198301599A (cs)
HU (1) HU193157B (cs)
IE (1) IE56056B1 (cs)
IL (1) IL68004A (cs)
NO (1) NO155932C (cs)
NZ (1) NZ203417A (cs)
PH (1) PH17908A (cs)
PL (1) PL138758B1 (cs)
PT (1) PT76298B (cs)
RO (1) RO86647B (cs)
ZA (1) ZA831356B (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
EP0136831B1 (en) * 1983-09-06 1988-11-09 Pfizer Inc. Azahomoerythromycin b derivatives and intermediates thereof
JPS60120895A (ja) * 1983-12-02 1985-06-28 Taisho Pharmaceut Co Ltd 6−0−メチル−2′−0,ν−ビス(ベンジルオキシカルボニル)−ν−デメチルエリスロマイシンaの製法
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシン類の製法
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
US4783811A (en) * 1984-12-27 1988-11-08 Texas Instruments Incorporated Method and apparatus for determining syllable boundaries
US4640910A (en) * 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
US4681872A (en) * 1985-11-12 1987-07-21 Abbott Laboratories Erythromycin A 11,12-carbonate and method of use
US4833236A (en) * 1986-05-02 1989-05-23 Taisho Pharmaceutical Co., Ltd. Erythromycin derivatives
DK0699207T3 (da) * 1993-05-19 1997-12-08 Pfizer Mellemprodukt til azithromycin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
SI1532131T1 (sl) * 2002-08-29 2009-04-30 Pfizer Motilidne spojine
WO2004101592A1 (ja) * 2003-05-19 2004-11-25 Taisho Pharmaceutical Co., Ltd. エリスロマイシンa誘導体の製造方法
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3417077A (en) * 1966-05-16 1968-12-17 Lilly Co Eli Erythromycin derivative and process for the preparation thereof
US3884904A (en) * 1973-06-21 1975-05-20 Abbott Lab 11-Substituted erythromycin B derivatives
US3884903A (en) * 1973-06-21 1975-05-20 Abbott Lab 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives
SE445223B (sv) * 1977-02-04 1986-06-09 Pfizer Sett att framstella 4"-amino-erytomylin-a-derivat
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives

Also Published As

Publication number Publication date
FI74287C (fi) 1988-01-11
JPS58159499A (ja) 1983-09-21
GT198301599A (es) 1984-09-13
PL138758B1 (en) 1986-10-31
PH17908A (en) 1985-01-25
NZ203417A (en) 1985-10-11
FI74287B (fi) 1987-09-30
PL240764A1 (en) 1985-01-02
IE830411L (en) 1983-09-01
ZA831356B (en) 1983-11-30
KR840003647A (ko) 1984-09-15
RO86647B (ro) 1985-05-01
FI830654A0 (fi) 1983-02-28
EG16630A (en) 1991-03-30
KR850000965B1 (ko) 1985-07-02
JPH0140039B2 (cs) 1989-08-24
DK157495C (da) 1990-06-11
IL68004A0 (en) 1983-06-15
RO86647A (ro) 1985-04-17
DK96783A (da) 1983-09-02
CS235049B2 (en) 1985-04-16
DK157495B (da) 1990-01-15
EP0087905B1 (en) 1985-08-21
DK96783D0 (da) 1983-02-28
ATE15048T1 (de) 1985-09-15
ES8403928A1 (es) 1984-04-01
NO155932B (no) 1987-03-16
US4382085A (en) 1983-05-03
CS235036B2 (en) 1985-04-16
IE56056B1 (en) 1991-04-10
IL68004A (en) 1986-11-30
DE3360589D1 (en) 1985-09-26
AU555208B2 (en) 1986-09-18
NO155932C (no) 1987-06-24
PT76298B (en) 1986-01-27
ES8602837A1 (es) 1985-11-16
ES526323A0 (es) 1985-11-16
AU1189883A (en) 1983-09-08
EP0087905A1 (en) 1983-09-07
FI830654L (fi) 1983-09-02
GR78094B (cs) 1984-09-26
CA1178596A (en) 1984-11-27
NO830686L (no) 1983-09-02
CS235048B2 (en) 1985-04-16
PT76298A (en) 1983-03-01
ES520177A0 (es) 1984-04-01
HU193157B (en) 1987-08-28

Similar Documents

Publication Publication Date Title
DD211565A5 (de) Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel
CH655728A5 (de) Erythromycin a-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung.
DD216017A5 (de) Verfahren zur herstellung von 4"-epi-9-desoxo-9a-methyl-9a-aza-9a-homoerythromycin a
DD143779A5 (de) Verfahren zur herstellung von 4''-desoxy-4''-oxo-erythromycin-a-derivaten
DE2900118C2 (cs)
US4382086A (en) 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A
DE2804517C3 (de) Epimere 4"-substituierte Aminoderivate des Oleandomycins und deren Verwendung bei der Bekämpfung von Bakterien
CH629820A5 (en) Process for the preparation of 9,3'',4''-trialkanoyl derivatives of the substance SF-837-M1
DE2740950A1 (de) Verfahren zur herstellung von flavonen
DE2804507C2 (de) 4"-Desoxy-4"-amino-erythromycin-A und dessen Derivate sowie diese Verbindungen enthaltende antibakterielle Mittel
DE2804509C2 (de) 4"-Amino-oleandomycin-Derivate und diese Verbindungen enthaltende antibakterielle Mittel
DE2607459A1 (de) Neue antibiotische verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2302935A1 (de) Semi-synthetische antibiotika mit makrocyclischer lactonstruktur
CH615197A5 (en) Process for the preparation of antibiotic compounds
US4429116A (en) Alkylated oleandomycin containing compounds
DE2900119C2 (de) 4''-Desoxy-4''-carbamat- und -dithiocarbamat-Derivate des 11-Acetyl-oleandomycins und deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2856534A1 (de) 11-alkanoyl-4''desoxy-4''-isonitrilo-oleandomycin-derivate und ihre verwendung
DE2900120C2 (cs)
AT361629B (de) Verfahren zur herstellung von neuen 4''- -erythromycin-a-derivaten
AT360159B (de) Verfahren zur herstellung von neuen 4''-amino- -oleandomycinen
AT371481B (de) Verfahren zur herstellung von neuen 4''-deoxy-4''-acylamidoderivaten von erythromycin
DE3041130A1 (de) Antibiotisch wirksames macrolid
DD215787A5 (de) Verfahren zur herstellung neuer zwischenstufen fuer antibakterielle erythromycin-derivate
DE2821189A1 (de) Coriolinderivate, deren herstellung und diese enthaltende pharmazeutische praeparate
CH634056A5 (en) Process for preparing a derivative of streptovaricinone C

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee