DD206379A5 - Verfahren zur herstellung von ergopeptinderivaten - Google Patents

Verfahren zur herstellung von ergopeptinderivaten Download PDF

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Publication number
DD206379A5
DD206379A5 DD82242325A DD24232582A DD206379A5 DD 206379 A5 DD206379 A5 DD 206379A5 DD 82242325 A DD82242325 A DD 82242325A DD 24232582 A DD24232582 A DD 24232582A DD 206379 A5 DD206379 A5 DD 206379A5
Authority
DD
German Democratic Republic
Prior art keywords
hydrogen
formula
compounds
acid
acid addition
Prior art date
Application number
DD82242325A
Other languages
German (de)
English (en)
Inventor
Hans Kobel
Jean-Jacques Sanglier
Hans Tscherter
Georg Bolliger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DD206379A5 publication Critical patent/DD206379A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DD82242325A 1981-08-07 1982-08-06 Verfahren zur herstellung von ergopeptinderivaten DD206379A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5104/81A CH649300A5 (de) 1981-08-07 1981-08-07 Ergopeptinderivate, ihre herstellung und verwendung.

Publications (1)

Publication Number Publication Date
DD206379A5 true DD206379A5 (de) 1984-01-25

Family

ID=4287999

Family Applications (2)

Application Number Title Priority Date Filing Date
DD82242325A DD206379A5 (de) 1981-08-07 1982-08-06 Verfahren zur herstellung von ergopeptinderivaten
DD82256213A DD211582A5 (de) 1981-08-07 1982-08-06 Verfahren zur herstellung von ergopeptinderivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD82256213A DD211582A5 (de) 1981-08-07 1982-08-06 Verfahren zur herstellung von ergopeptinderivaten

Country Status (27)

Country Link
US (3) US4542135A (fi)
JP (1) JPS5843982A (fi)
AT (1) AT382156B (fi)
AU (1) AU558414B2 (fi)
BE (1) BE894046A (fi)
CA (1) CA1191802A (fi)
CH (1) CH649300A5 (fi)
CS (1) CS235303B2 (fi)
DD (2) DD206379A5 (fi)
DE (1) DE3228230A1 (fi)
DK (1) DK352082A (fi)
ES (2) ES8402348A1 (fi)
FI (1) FI72979C (fi)
FR (1) FR2511003B1 (fi)
GB (1) GB2109795B (fi)
GR (1) GR77262B (fi)
HU (2) HU190405B (fi)
IE (1) IE53647B1 (fi)
IL (1) IL66471A (fi)
IT (1) IT1152489B (fi)
MY (1) MY8600311A (fi)
NL (1) NL8203067A (fi)
NZ (1) NZ201504A (fi)
PH (1) PH22998A (fi)
PT (1) PT75384B (fi)
SE (1) SE452011B (fi)
ZA (1) ZA825727B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
JPS60104129A (ja) * 1983-11-11 1985-06-08 Hitachi Ltd フッ素含有ポリアミド酸誘導体及びポリイミドの製造方法
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
HU193317B (en) * 1985-06-12 1987-09-28 Richter Gedeon Vegyeszet Process for producing 2-bromo-alpha-ergochristin
DE69330601T2 (de) * 1992-12-24 2002-07-04 Pharmacia & Upjohn Spa Serotoninergische ergolin derivate
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
US20070022720A1 (en) * 2005-07-27 2007-02-01 The Toro Company Cleaner for cooling system screen of outdoor power equipment unit
US8710092B2 (en) * 2009-12-23 2014-04-29 Map Pharmaceuticals, Inc. Substituted indolo 4,3 FG quinolines useful for treating migraine
BR112013033339A2 (pt) 2011-06-23 2016-08-16 Map Pharmaceuticals Inc análogos de fluorergolina
WO2013095707A1 (en) 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
CA2859175A1 (en) 2011-12-21 2013-06-27 Map Pharmaceuticals, Inc. Novel neuromodulatory compounds
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
CZ2013590A3 (cs) * 2013-07-25 2014-09-03 Teva Czech Industries S.R.O. Izolovaný kmen houby Claviceps purpurea (Fr.) Tul., CCM 8404
CN113308442B (zh) * 2021-04-28 2023-06-27 天津大学 重组酿酒酵母菌株及其构建方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314959A (en) * 1961-05-10 1967-04-18 Sandoz Ltd Intermediates for the synthesis of ergot alkaloids
FR2292M (fr) * 1962-06-27 1964-01-27 Sandoz Sa Médicament a base d'une combinaison de dihydro-ergotamine, de caféine et d'une hydantoine.
CH602765A5 (fi) * 1974-09-27 1978-07-31 Sandoz Ag
CH602766A5 (en) * 1974-09-27 1978-07-31 Sandoz Ag 10-Alpha-methoxy-di:hydro-beta-ergosine derivs.
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
CH626373A5 (fi) * 1977-02-22 1981-11-13 Sandoz Ag
GB1584464A (en) * 1977-04-19 1981-02-11 Farmaceutici Italia Ergot alkaloids
DE2717953A1 (de) * 1977-04-22 1978-10-26 Sandoz Ag Neue therapeutische mischung und verfahren zu deren herstellung
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
CH636011A5 (en) * 1978-01-01 1983-05-13 Sandoz Ag Administration forms for organic compounds
EP0003286B1 (de) * 1978-01-20 1982-03-24 Sandoz Ag Ergopeptidalkaloid-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE2803543A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Ergopeptidalkaloidderivate, ihre verwendung und herstellung
YU40046B (en) * 1978-09-04 1985-06-30 Lek Tovarna Farmacevtskih Process for preparing 2-bromo-9,10-dihydroergosine
US4609731A (en) * 1979-10-10 1986-09-02 Sandoz Ltd. Process for brominating ergot alkaloids
DD200571A1 (de) * 1981-07-22 1983-05-18 Alfred Baumert Verfahren zur herstellung von ergopeptinen mit modifiziertem prolinteil
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
AU558414B2 (en) 1987-01-29
US4681880A (en) 1987-07-21
AT382156B (de) 1987-01-26
SE8204585L (sv) 1983-02-08
PH22998A (en) 1989-02-24
CS235303B2 (en) 1985-05-15
MY8600311A (en) 1986-12-31
NL8203067A (nl) 1983-03-01
DD211582A5 (de) 1984-07-18
IT1152489B (it) 1986-12-31
US4804660A (en) 1989-02-14
IE53647B1 (en) 1989-01-04
CH649300A5 (de) 1985-05-15
IE821906L (en) 1983-02-07
NZ201504A (en) 1986-08-08
HU193373B (en) 1987-09-28
ATA302682A (de) 1986-06-15
DE3228230A1 (de) 1983-02-17
GB2109795A (en) 1983-06-08
SE452011B (sv) 1987-11-09
DK352082A (da) 1983-02-08
FR2511003A1 (fr) 1983-02-11
FI72979B (fi) 1987-04-30
JPH0437836B2 (fi) 1992-06-22
AU8678582A (en) 1983-03-03
ES514766A0 (es) 1984-01-16
GR77262B (fi) 1984-09-11
JPS5843982A (ja) 1983-03-14
FR2511003B1 (fr) 1986-12-05
HUT37960A (en) 1986-03-28
BE894046A (fr) 1983-02-07
CA1191802A (en) 1985-08-13
SE8204585D0 (sv) 1982-08-05
IL66471A0 (en) 1982-12-31
FI822670L (fi) 1983-02-08
FI822670A0 (fi) 1982-07-30
HU190405B (en) 1986-09-29
ES8504825A1 (es) 1985-04-16
ES526119A0 (es) 1985-04-16
GB2109795B (en) 1985-07-03
IT8222768A0 (it) 1982-08-06
ES8402348A1 (es) 1984-01-16
US4542135A (en) 1985-09-17
ZA825727B (en) 1984-03-28
FI72979C (fi) 1987-08-10
IL66471A (en) 1986-02-28
PT75384B (en) 1985-06-28
PT75384A (en) 1982-09-01

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