AT382156B - Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden - Google Patents

Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden

Info

Publication number
AT382156B
AT382156B AT0302682A AT302682A AT382156B AT 382156 B AT382156 B AT 382156B AT 0302682 A AT0302682 A AT 0302682A AT 302682 A AT302682 A AT 302682A AT 382156 B AT382156 B AT 382156B
Authority
AT
Austria
Prior art keywords
thiapeptidergotal
calalid
producing new
new cyclic
cyclic
Prior art date
Application number
AT0302682A
Other languages
English (en)
Other versions
ATA302682A (de
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to AT134285A priority Critical patent/AT384437B/de
Publication of ATA302682A publication Critical patent/ATA302682A/de
Application granted granted Critical
Publication of AT382156B publication Critical patent/AT382156B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
AT0302682A 1981-08-07 1982-08-06 Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden AT382156B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT134285A AT384437B (de) 1981-08-07 1985-05-06 Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5104/81A CH649300A5 (de) 1981-08-07 1981-08-07 Ergopeptinderivate, ihre herstellung und verwendung.

Publications (2)

Publication Number Publication Date
ATA302682A ATA302682A (de) 1986-06-15
AT382156B true AT382156B (de) 1987-01-26

Family

ID=4287999

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0302682A AT382156B (de) 1981-08-07 1982-08-06 Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden

Country Status (27)

Country Link
US (3) US4542135A (de)
JP (1) JPS5843982A (de)
AT (1) AT382156B (de)
AU (1) AU558414B2 (de)
BE (1) BE894046A (de)
CA (1) CA1191802A (de)
CH (1) CH649300A5 (de)
CS (1) CS235303B2 (de)
DD (2) DD206379A5 (de)
DE (1) DE3228230A1 (de)
DK (1) DK352082A (de)
ES (2) ES8402348A1 (de)
FI (1) FI72979C (de)
FR (1) FR2511003B1 (de)
GB (1) GB2109795B (de)
GR (1) GR77262B (de)
HU (2) HU190405B (de)
IE (1) IE53647B1 (de)
IL (1) IL66471A (de)
IT (1) IT1152489B (de)
MY (1) MY8600311A (de)
NL (1) NL8203067A (de)
NZ (1) NZ201504A (de)
PH (1) PH22998A (de)
PT (1) PT75384B (de)
SE (1) SE452011B (de)
ZA (1) ZA825727B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
JPS60104129A (ja) * 1983-11-11 1985-06-08 Hitachi Ltd フッ素含有ポリアミド酸誘導体及びポリイミドの製造方法
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
HU193317B (en) * 1985-06-12 1987-09-28 Richter Gedeon Vegyeszet Process for producing 2-bromo-alpha-ergochristin
WO1994014806A1 (en) * 1992-12-24 1994-07-07 Farmitalia Carlo Erba S.R.L. Serotoninergic ergoline derivatives
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
US20070022720A1 (en) * 2005-07-27 2007-02-01 The Toro Company Cleaner for cooling system screen of outdoor power equipment unit
WO2011079313A1 (en) * 2009-12-23 2011-06-30 Map Pharmaceuticals, Inc. Novel ergoline analogs
CN103827113A (zh) 2011-06-23 2014-05-28 Map药物公司 新型氟麦角碱类似物
CA2859173A1 (en) 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
AU2012355983A1 (en) 2011-12-21 2015-01-22 Map Pharmaceuticals, Inc. Novel neuromodulatory compounds
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
CZ304709B6 (cs) * 2013-07-25 2014-09-03 Teva Czech Industries S.R.O. Izolovaný kmen houby Claviceps purpurea (Fr.) Tul., CCM 8404
CN113308442B (zh) * 2021-04-28 2023-06-27 天津大学 重组酿酒酵母菌株及其构建方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314959A (en) * 1961-05-10 1967-04-18 Sandoz Ltd Intermediates for the synthesis of ergot alkaloids
FR2292M (fr) * 1962-06-27 1964-01-27 Sandoz Sa Médicament a base d'une combinaison de dihydro-ergotamine, de caféine et d'une hydantoine.
CH602765A5 (de) * 1974-09-27 1978-07-31 Sandoz Ag
CH602766A5 (en) * 1974-09-27 1978-07-31 Sandoz Ag 10-Alpha-methoxy-di:hydro-beta-ergosine derivs.
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
CH626373A5 (de) * 1977-02-22 1981-11-13 Sandoz Ag
GB1584464A (en) * 1977-04-19 1981-02-11 Farmaceutici Italia Ergot alkaloids
DE2717953A1 (de) * 1977-04-22 1978-10-26 Sandoz Ag Neue therapeutische mischung und verfahren zu deren herstellung
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
CH636011A5 (en) * 1978-01-01 1983-05-13 Sandoz Ag Administration forms for organic compounds
DE2962303D1 (en) * 1978-01-20 1982-04-29 Sandoz Ag Derivatives of ergopeptide alkaloids, process for their preparation and pharmaceutical compositions containing them
DE2803543A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Ergopeptidalkaloidderivate, ihre verwendung und herstellung
YU40046B (en) * 1978-09-04 1985-06-30 Lek Tovarna Farmacevtskih Process for preparing 2-bromo-9,10-dihydroergosine
US4609731A (en) * 1979-10-10 1986-09-02 Sandoz Ltd. Process for brominating ergot alkaloids
DD200571A1 (de) * 1981-07-22 1983-05-18 Alfred Baumert Verfahren zur herstellung von ergopeptinen mit modifiziertem prolinteil
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
ES514766A0 (es) 1984-01-16
CS235303B2 (en) 1985-05-15
HU190405B (en) 1986-09-29
US4804660A (en) 1989-02-14
PT75384B (en) 1985-06-28
ATA302682A (de) 1986-06-15
IL66471A (en) 1986-02-28
SE8204585D0 (sv) 1982-08-05
CA1191802A (en) 1985-08-13
AU558414B2 (en) 1987-01-29
FR2511003B1 (fr) 1986-12-05
FI822670A0 (fi) 1982-07-30
SE8204585L (sv) 1983-02-08
FR2511003A1 (fr) 1983-02-11
MY8600311A (en) 1986-12-31
BE894046A (fr) 1983-02-07
HUT37960A (en) 1986-03-28
GB2109795A (en) 1983-06-08
DD206379A5 (de) 1984-01-25
ES526119A0 (es) 1985-04-16
JPH0437836B2 (de) 1992-06-22
IE53647B1 (en) 1989-01-04
US4542135A (en) 1985-09-17
GB2109795B (en) 1985-07-03
IT1152489B (it) 1986-12-31
IL66471A0 (en) 1982-12-31
DK352082A (da) 1983-02-08
US4681880A (en) 1987-07-21
ZA825727B (en) 1984-03-28
ES8504825A1 (es) 1985-04-16
JPS5843982A (ja) 1983-03-14
NZ201504A (en) 1986-08-08
IT8222768A0 (it) 1982-08-06
CH649300A5 (de) 1985-05-15
SE452011B (sv) 1987-11-09
GR77262B (de) 1984-09-11
PH22998A (en) 1989-02-24
FI72979B (fi) 1987-04-30
HU193373B (en) 1987-09-28
FI72979C (fi) 1987-08-10
NL8203067A (nl) 1983-03-01
ES8402348A1 (es) 1984-01-16
AU8678582A (en) 1983-03-03
DE3228230A1 (de) 1983-02-17
FI822670L (fi) 1983-02-08
PT75384A (en) 1982-09-01
IE821906L (en) 1983-02-07
DD211582A5 (de) 1984-07-18

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