AT386199B - Verfahren zur herstellung von neuen 2-piperazinopyrimidinen - Google Patents
Verfahren zur herstellung von neuen 2-piperazinopyrimidinenInfo
- Publication number
- AT386199B AT386199B AT0127682A AT127682A AT386199B AT 386199 B AT386199 B AT 386199B AT 0127682 A AT0127682 A AT 0127682A AT 127682 A AT127682 A AT 127682A AT 386199 B AT386199 B AT 386199B
- Authority
- AT
- Austria
- Prior art keywords
- piperazinopyrimidines
- producing new
- producing
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8106924A FR2503162A1 (fr) | 1981-04-07 | 1981-04-07 | Nouveaux derives de piperazino-2 pyrimidine, procedes pour leur preparation et leur utilisation comme medicaments ou comme intermediaires pour la fabrication de medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA127682A ATA127682A (de) | 1987-12-15 |
| AT386199B true AT386199B (de) | 1988-07-11 |
Family
ID=9257094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0127682A AT386199B (de) | 1981-04-07 | 1982-03-31 | Verfahren zur herstellung von neuen 2-piperazinopyrimidinen |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4535080A (de) |
| EP (1) | EP0063509B1 (de) |
| JP (1) | JPS57179167A (de) |
| AR (1) | AR231442A1 (de) |
| AT (1) | AT386199B (de) |
| AU (1) | AU549748B2 (de) |
| CA (1) | CA1175427A (de) |
| DE (1) | DE3262374D1 (de) |
| DK (1) | DK156722C (de) |
| ES (4) | ES8306745A1 (de) |
| FI (1) | FI78909C (de) |
| FR (1) | FR2503162A1 (de) |
| GR (1) | GR77331B (de) |
| HU (1) | HU187673B (de) |
| IE (1) | IE52872B1 (de) |
| IL (1) | IL65422A (de) |
| MA (1) | MA19438A1 (de) |
| MX (1) | MX156087A (de) |
| NO (1) | NO158739C (de) |
| PT (1) | PT74712B (de) |
| ZA (1) | ZA822344B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3305524A1 (de) * | 1983-02-18 | 1984-08-23 | Celamerck Gmbh & Co Kg, 6507 Ingelheim | Neue pyrimidinderivate |
| DE3321969A1 (de) * | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| JPS6143173A (ja) * | 1984-08-06 | 1986-03-01 | Mitsui Petrochem Ind Ltd | 新規ピリミジン誘導体およびその製法 |
| JP2561689B2 (ja) * | 1986-02-24 | 1996-12-11 | 三井石油化学工業株式会社 | 神経疾患用治療薬 |
| US4959368A (en) * | 1986-02-24 | 1990-09-25 | Mitsui Petrochemical Industries Ltd. | Therapeutic agent for neurological diseases |
| WO1989000423A1 (en) | 1987-07-09 | 1989-01-26 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
| US4910204A (en) * | 1988-06-28 | 1990-03-20 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
| FI895821A0 (fi) * | 1988-12-07 | 1989-12-05 | Wellcome Found | Farmaceutiskt aktiva cns foereningar. |
| EP1984390A2 (de) * | 2006-01-23 | 2008-10-29 | Board of Trustees of Michigan State University | Verfahren für die züchtung von glyphosateresistenten pflanzen und zusammensetzungen davon |
| EP2326627A1 (de) * | 2008-08-20 | 2011-06-01 | Schering Corporation | Substituierte pyridin- und pyrimidinderivate und ihre verwendung bei der behandlung von virusinfektionen |
| PT2432767E (pt) * | 2009-05-19 | 2013-07-25 | Dow Agrosciences Llc | Compostos e métodos para controlo de fungos |
| CN103204816B (zh) * | 2012-01-16 | 2016-04-27 | 中国人民解放军军事医学科学院毒物药物研究所 | 哌嗪基嘧啶类衍生物及其制备方法和用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1620419B (de) * | Science-Union Et Cie., Societe Francaise De Recherche Medicale, Suresnes (Frankreich) | 1,4-substituierte Piperazine und Verfahren zu ihrer Herstellung | ||
| US2543972A (en) * | 1947-11-12 | 1951-03-06 | American Cyanamid Co | 1,4-disubstituted piperazines |
| FR2311776B1 (de) * | 1975-05-23 | 1978-09-08 | Sogeras |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2257294B1 (de) * | 1973-07-06 | 1977-07-01 | Ugine Kuhlmann | |
| NL129219C (de) * | 1965-12-16 | |||
| US3980781A (en) * | 1966-03-31 | 1976-09-14 | Imperial Chemical Industries Limited | Fungicidal composition and method containing 2-amino-pyrimidines |
| FR2173746B1 (de) * | 1972-03-01 | 1975-04-25 | Ugine Kuhlmann | |
| FR2244520B1 (de) * | 1973-07-06 | 1977-02-04 | Ugine Kuhlmann | |
| JPS578104B2 (de) * | 1973-09-20 | 1982-02-15 | ||
| GB1523274A (en) * | 1974-08-05 | 1978-08-31 | Ici Ltd | Herbicidal compositions containing substituted pyrimidine |
| FR2281117A2 (fr) * | 1974-08-09 | 1976-03-05 | Ugine Kuhlmann | Nouvelles piperazino-pyrimidines utilisables comme medicaments |
| US4166852A (en) * | 1974-08-09 | 1979-09-04 | Produits Chimiques Ugine Kuhlmann | Piperazino-pyrimidines and their use as spasmolytic agents |
| FR2417507A2 (fr) * | 1977-07-28 | 1979-09-14 | Ugine Kuhlmann | Diamino-2,4 (ou -4,6) methylthio-5 pyrimidines herbicides |
-
1981
- 1981-04-07 FR FR8106924A patent/FR2503162A1/fr active Granted
-
1982
- 1982-03-11 GR GR67575A patent/GR77331B/el unknown
- 1982-03-26 DE DE8282400551T patent/DE3262374D1/de not_active Expired
- 1982-03-26 EP EP82400551A patent/EP0063509B1/de not_active Expired
- 1982-03-31 AT AT0127682A patent/AT386199B/de not_active IP Right Cessation
- 1982-04-01 IE IE774/82A patent/IE52872B1/en unknown
- 1982-04-01 MX MX192097A patent/MX156087A/es unknown
- 1982-04-05 DK DK154382A patent/DK156722C/da not_active IP Right Cessation
- 1982-04-05 ZA ZA822344A patent/ZA822344B/xx unknown
- 1982-04-05 IL IL65422A patent/IL65422A/xx unknown
- 1982-04-05 MA MA19642A patent/MA19438A1/fr unknown
- 1982-04-05 AR AR289012A patent/AR231442A1/es active
- 1982-04-06 FI FI821203A patent/FI78909C/fi not_active IP Right Cessation
- 1982-04-06 JP JP57057179A patent/JPS57179167A/ja active Pending
- 1982-04-06 NO NO821159A patent/NO158739C/no unknown
- 1982-04-06 PT PT74712A patent/PT74712B/pt unknown
- 1982-04-06 ES ES511224A patent/ES8306745A1/es not_active Expired
- 1982-04-07 CA CA000400630A patent/CA1175427A/fr not_active Expired
- 1982-04-07 HU HU821067A patent/HU187673B/hu not_active IP Right Cessation
- 1982-04-07 AU AU82450/82A patent/AU549748B2/en not_active Ceased
-
1983
- 1983-01-13 ES ES518974A patent/ES518974A0/es active Granted
- 1983-01-13 ES ES518975A patent/ES518975A0/es active Granted
- 1983-01-13 ES ES518976A patent/ES8400429A1/es not_active Expired
- 1983-08-24 US US06/525,799 patent/US4535080A/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1620419B (de) * | Science-Union Et Cie., Societe Francaise De Recherche Medicale, Suresnes (Frankreich) | 1,4-substituierte Piperazine und Verfahren zu ihrer Herstellung | ||
| US2543972A (en) * | 1947-11-12 | 1951-03-06 | American Cyanamid Co | 1,4-disubstituted piperazines |
| FR2311776B1 (de) * | 1975-05-23 | 1978-09-08 | Sogeras |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AT377524B (de) | Verfahren zur herstellung von neuen anthracyclinglycosiden | |
| AT382612B (de) | Verfahren zur herstellung von neuen arylcyclobutylalkylaminen | |
| AT384017B (de) | Verfahren zur herstellung von neuen hydroxyaminoestern | |
| ATA125383A (de) | Verfahren zur herstellung von neuen benzoazacycloalkyl-spiro-imidazolidinen | |
| ATA206483A (de) | Verfahren zur herstellung von neuen mitosanderivaten | |
| AT382638B (de) | Verfahren zur herstellung von neuen trehaloselipiden | |
| AT381091B (de) | Verfahren zur herstellung von neuen ergolinderivaten | |
| AT386199B (de) | Verfahren zur herstellung von neuen 2-piperazinopyrimidinen | |
| AT375943B (de) | Verfahren zur herstellung von neuen mitosanverbindungen | |
| AT386828B (de) | Verfahren zur herstellung von neuen acylaminomitosanen | |
| AT380683B (de) | Verfahren zur herstellung von neuen diaminophenolaethern | |
| AT376222B (de) | Verfahren zur herstellung von neuen azinorifamycinverbindungen | |
| AT380477B (de) | Verfahren zur herstellung von neuen spirothiazolidindion-derivaten | |
| AT376679B (de) | Verfahren zur herstellung von neuen bisindolalkaloiden | |
| AT384214B (de) | Verfahren zur herstellung von neuen mercaptoacylcarnitinen | |
| AT387385B (de) | Verfahren zur herstellung von neuen substituierten 1-pyridyloxy-3-indolylalkylamino-2-propanolen | |
| AT377264B (de) | Verfahren zur herstellung von neuen nitrosoharnstoffderivaten | |
| AT381318B (de) | Verfahren zur herstellung von neuen nitrosoharnstoffderivaten | |
| AT373231B (de) | Verfahren zur herstellung von neuen alkoxyalkanoyl-carnitinhydrohalogeniden | |
| AT386408B (de) | Verfahren zur herstellung von neuen thioalkanoyl- carnitinen | |
| AT381939B (de) | Verfahren zur herstellung von neuen azaspiroalkandionen | |
| ATA354581A (de) | Verfahren zur herstellung von neuen 11-hydroxy-13 -oxa-postaglandinderivaten | |
| AT378776B (de) | Verfahren zur herstellung von neuen anthracyclinglycosiden | |
| ATA67481A (de) | Verfahren zur herstellung von neuen androstancarbothioaten | |
| AT379389B (de) | Verfahren zur herstellung von neuen 4-chinolonderivaten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |