CY1126046T1 - Διαλυμα συντηρησης νουκλεïκων οξεων και μεθοδοι χρησης - Google Patents

Διαλυμα συντηρησης νουκλεïκων οξεων και μεθοδοι χρησης

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Publication number
CY1126046T1
CY1126046T1 CY20231100269T CY231100269T CY1126046T1 CY 1126046 T1 CY1126046 T1 CY 1126046T1 CY 20231100269 T CY20231100269 T CY 20231100269T CY 231100269 T CY231100269 T CY 231100269T CY 1126046 T1 CY1126046 T1 CY 1126046T1
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CY
Cyprus
Prior art keywords
methods
nucleic acid
compositions
agent
tris
Prior art date
Application number
CY20231100269T
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English (en)
Inventor
Federico Carlos Arejola Gaeta
Original Assignee
Spectrum Solutions L.L.C.
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62839045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1126046(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Spectrum Solutions L.L.C. filed Critical Spectrum Solutions L.L.C.
Publication of CY1126046T1 publication Critical patent/CY1126046T1/el

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Γνωστοποιούνται συνθέσεις συντήρησης νουκλεϊκού οξέος και μέθοδοι παραγωγής και χρήσης των ιδίων. Οι συνθέσεις περιλαμβάνουν έναν φορέα, έναν χαοτροπικό παράγοντα, έναν ρυθμιστικό παράγοντα, έναν χηλικό παράγοντα, έναν επιφανειοδραστικό παράγοντα, μία αλκοόλη, ένα οξύ και ένα βλεννολυτικό παράγοντα. Συνθέσεις ως υδατικά διαλύματα μπορούν να περιλαμβάνουν νερό ως φορέα. Προτιμώμενες εφαρμογές περιλαμβάνουν νερό, θειοκυανική γουανιδίνη, ρυθμιστικό διάλυμα Tris (τρις(υδροξυμεθυλο)αμινομεθάνιο), EDTA (αιθυλενοδιαμινοτετραοξικό οξύ), SLS (λαυρυλο-θειικό νάτριο), SDA 3C (ειδικά μετουσιωμένη αλκοόλη), HC1 και Ν-ακετυλο-L-κυστεΐνη. Μερικές εφαρμογές περιλαμβάνουν μια χρωματιστή βαφή ως οπτικό δείκτη. Μέθοδοι παραγωγής περιλαμβάνουν συνδυασμό των συστατικών σε ένα μίγμα, όπως ένα υδατικό διάλυμα. Μέθοδοι χρήσης περιλαμβάνουν παροχή ενός βιολογικού δείγματος που περιλαμβάνει νουκλεϊκό οξύ και επαφή του βιολογικού δείγματος με τη σύνθεση. Τυποποιημένες συσκευασίες (κιτ) περιλαμβάνουν τη σύνθεση που διατίθεται σε ένα τμήμα συσκευής συλλογής βιολογικού δείγματος.
CY20231100269T 2017-01-16 2023-06-07 Διαλυμα συντηρησης νουκλεïκων οξεων και μεθοδοι χρησης CY1126046T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762446818P 2017-01-16 2017-01-16
PCT/US2018/013862 WO2018132827A1 (en) 2017-01-16 2018-01-16 Nucleic acid preservation solution and methods of manufacture and use

Publications (1)

Publication Number Publication Date
CY1126046T1 true CY1126046T1 (el) 2023-11-15

Family

ID=62839045

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20231100269T CY1126046T1 (el) 2017-01-16 2023-06-07 Διαλυμα συντηρησης νουκλεïκων οξεων και μεθοδοι χρησης

Country Status (17)

Country Link
US (4) US10174362B2 (el)
EP (3) EP4372099A3 (el)
JP (3) JP6652692B2 (el)
CN (2) CN113801876A (el)
CA (1) CA3042088A1 (el)
CY (1) CY1126046T1 (el)
DK (1) DK3568475T3 (el)
ES (1) ES2942577T3 (el)
FI (1) FI3568475T3 (el)
HR (1) HRP20230345T1 (el)
HU (1) HUE062204T2 (el)
LT (1) LT3568475T (el)
MX (2) MX2019006767A (el)
PL (1) PL3568475T3 (el)
PT (1) PT3568475T (el)
SI (1) SI3568475T1 (el)
WO (1) WO2018132827A1 (el)

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CN111218444B (zh) * 2020-04-24 2020-09-01 广州安必平医药科技股份有限公司 一种痰液保存液
CN111690640B (zh) * 2020-06-22 2023-10-03 广州东盛生物科技有限公司 一种高度兼容磁珠法病毒核酸提取试剂盒的病毒保存液
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CN112176025B (zh) * 2020-10-12 2022-05-24 广东南芯医疗科技有限公司 一种核酸保存液及其制备方法和应用
CN112760318B (zh) * 2020-12-30 2023-11-17 苏州白垩纪生物科技有限公司 一种用于稳定核酸分子的试剂组合物及其应用
CN113373031B (zh) * 2021-08-13 2021-11-16 北京健为医学检验实验室有限公司 一种喷雾型的游离dna样本保存管及应用
CN113736755B (zh) * 2021-08-18 2024-01-19 江苏默乐生物科技股份有限公司 一种可常温保存的灭活型病毒保存液及其制备方法
CN114235986A (zh) * 2021-11-25 2022-03-25 浙江艾兰得生物科技有限公司 维生素b1、b2、b6、烟酸、烟酰胺含量的高效液相色谱检测方法
CN116555248B (zh) * 2023-07-10 2023-10-20 北京凡知医学科技有限公司 一种细菌中高分子量dna提取试剂盒及提取方法
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PL3568475T3 (pl) 2023-06-19
JP6652692B2 (ja) 2020-02-26
SI3568475T1 (sl) 2023-05-31
ES2942577T3 (es) 2023-06-02
CN110072999A (zh) 2019-07-30
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CA3042088A1 (en) 2018-07-19
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