BR112017022329A2 - métodos para detectar aglutinação e composições para uso na prática do mesmo - Google Patents
métodos para detectar aglutinação e composições para uso na prática do mesmoInfo
- Publication number
- BR112017022329A2 BR112017022329A2 BR112017022329A BR112017022329A BR112017022329A2 BR 112017022329 A2 BR112017022329 A2 BR 112017022329A2 BR 112017022329 A BR112017022329 A BR 112017022329A BR 112017022329 A BR112017022329 A BR 112017022329A BR 112017022329 A2 BR112017022329 A2 BR 112017022329A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- detecting
- compositions
- practice
- aspects
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/117—Modifications characterised by incorporating modified base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/197—Modifications characterised by incorporating a spacer/coupling moiety
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/113—PCR
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
são fornecidos métodos para detectar agentes de ligação a antígeno em amostras. aspectos dos métodos incluem detecção da agregação de agentes de ligação a antígeno com antígenos de ligação a polinucleotídeo por associação à base de proximidade sensitiva dos polinucleotídeos ligados a antígeno. aspectos dos métodos também incluem métodos para a detecção de tal associação à base de proximidade por meio de amplificação de ácido nucleico. adicionalmente, composições, por exemplo, reagentes, kits e aparelhos úteis na prática de várias modalidades dos métodos são fornecidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562149324P | 2015-04-17 | 2015-04-17 | |
PCT/US2016/027906 WO2016168711A1 (en) | 2015-04-17 | 2016-04-15 | Methods for detecting agglutination and compositions for use in practicing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017022329A2 true BR112017022329A2 (pt) | 2018-07-17 |
Family
ID=57127062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017022329A BR112017022329A2 (pt) | 2015-04-17 | 2016-04-15 | métodos para detectar aglutinação e composições para uso na prática do mesmo |
Country Status (10)
Country | Link |
---|---|
US (1) | US11149296B2 (pt) |
EP (2) | EP4123031A1 (pt) |
JP (1) | JP6822973B2 (pt) |
CN (1) | CN107614699A (pt) |
AU (1) | AU2016249392A1 (pt) |
BR (1) | BR112017022329A2 (pt) |
CA (1) | CA2982998A1 (pt) |
EA (1) | EA201792289A1 (pt) |
WO (1) | WO2016168711A1 (pt) |
ZA (1) | ZA201707114B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106591436A (zh) * | 2016-11-24 | 2017-04-26 | 湖南大学 | 用于检测人体内低丰度抗体的邻位连接核酸探针与试剂盒及其制备方法 |
AU2018243461A1 (en) | 2017-03-30 | 2019-10-24 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplex isotype-specific antibody detection |
CN109142730B (zh) * | 2018-06-14 | 2021-04-23 | 郑州大学第一附属医院 | 一种肺癌标志物抗-psip1自身抗体及其应用 |
CA3136684A1 (en) * | 2019-05-06 | 2020-11-12 | The Regents Of The University Of California | Non-hla markers of transplant rejection |
CN111323590B (zh) * | 2020-03-19 | 2022-04-22 | 福建省立医院 | 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用 |
CN111398584A (zh) * | 2020-03-20 | 2020-07-10 | 北京良芯生物科技发展有限公司 | 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法 |
CN111499724A (zh) * | 2020-04-15 | 2020-08-07 | 上海领潮生物新材料有限公司 | 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法 |
CN114316016B (zh) * | 2021-12-14 | 2023-11-10 | 江苏浩欧博生物医药股份有限公司 | 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒 |
CN115060912B (zh) * | 2022-06-23 | 2024-02-02 | 南京浦光生物科技有限公司 | 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法 |
EP4389913A1 (en) * | 2022-12-23 | 2024-06-26 | Universität Heidelberg | A pcr-elisa analogous antibody-free method for detecting a target nucleic acid in a sample |
Family Cites Families (36)
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US4292403A (en) * | 1978-08-24 | 1981-09-29 | Akzona Incorporated | Detection and/or determination of IgM, IgA, IgD and IgE immunoglobulins |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4883867A (en) | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
JP3392863B2 (ja) * | 1990-07-24 | 2003-03-31 | エフ.ホフマン ― ラ ロシュ アーゲー | 修飾核酸塩基を使用するインビトロ核酸増幅における非特異的増幅の低減 |
WO1993006482A1 (en) | 1991-09-16 | 1993-04-01 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes |
US5321130A (en) | 1992-02-10 | 1994-06-14 | Molecular Probes, Inc. | Unsymmetrical cyanine dyes with a cationic side chain |
EP1550729B1 (en) | 1992-09-25 | 2009-05-27 | Avipep Pty Limited | Target binding polypeptide comprising an IG-like VL domain linked to an IG-like VH domain |
US5410030A (en) | 1993-04-05 | 1995-04-25 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes containing pyridinium moieties |
US5436134A (en) | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
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EP1006197A1 (en) * | 1998-12-04 | 2000-06-07 | Transgene S.A. | Use of an immuno complex for the preparation of a therapeutic composition useful for transfecting a polynucleotide into macropinocyte cells |
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WO2005074417A2 (en) * | 2003-09-03 | 2005-08-18 | Salk Institute For Biological Studies | Multiple antigen detection assays and reagents |
EP1692514A4 (en) * | 2003-11-07 | 2008-04-09 | Hepgenics Pty Ltd | BINDING DOSING COMPONENTS |
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WO2013073932A1 (en) * | 2011-11-15 | 2013-05-23 | Erasmus University Medical Center Rotterdam | Methods and kits for detecting ige-expressing b cells |
-
2016
- 2016-04-15 US US15/566,594 patent/US11149296B2/en active Active
- 2016-04-15 CA CA2982998A patent/CA2982998A1/en not_active Abandoned
- 2016-04-15 WO PCT/US2016/027906 patent/WO2016168711A1/en active Application Filing
- 2016-04-15 BR BR112017022329A patent/BR112017022329A2/pt not_active IP Right Cessation
- 2016-04-15 EP EP22177391.4A patent/EP4123031A1/en active Pending
- 2016-04-15 JP JP2017554311A patent/JP6822973B2/ja active Active
- 2016-04-15 AU AU2016249392A patent/AU2016249392A1/en not_active Abandoned
- 2016-04-15 CN CN201680031621.3A patent/CN107614699A/zh active Pending
- 2016-04-15 EA EA201792289A patent/EA201792289A1/ru unknown
- 2016-04-15 EP EP16780915.1A patent/EP3283638B1/en active Active
-
2017
- 2017-10-19 ZA ZA2017/07114A patent/ZA201707114B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3283638A4 (en) | 2018-09-12 |
EP3283638A1 (en) | 2018-02-21 |
EA201792289A1 (ru) | 2018-04-30 |
CA2982998A1 (en) | 2016-10-20 |
US11149296B2 (en) | 2021-10-19 |
CN107614699A (zh) | 2018-01-19 |
JP2018512862A (ja) | 2018-05-24 |
WO2016168711A1 (en) | 2016-10-20 |
US20180100181A1 (en) | 2018-04-12 |
AU2016249392A1 (en) | 2017-11-16 |
JP6822973B2 (ja) | 2021-01-27 |
EP4123031A1 (en) | 2023-01-25 |
ZA201707114B (en) | 2019-02-27 |
EP3283638B1 (en) | 2022-06-08 |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2666 DE 08-02-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |