BR112018013381A2 - anticorpo especificamente ligante a antígenos derivados de miobacteria ou fragmento ligante a antígeno do mesmo - Google Patents

anticorpo especificamente ligante a antígenos derivados de miobacteria ou fragmento ligante a antígeno do mesmo

Info

Publication number
BR112018013381A2
BR112018013381A2 BR112018013381-7A BR112018013381A BR112018013381A2 BR 112018013381 A2 BR112018013381 A2 BR 112018013381A2 BR 112018013381 A BR112018013381 A BR 112018013381A BR 112018013381 A2 BR112018013381 A2 BR 112018013381A2
Authority
BR
Brazil
Prior art keywords
antigen
binding
myobacteria
same
antibody specifically
Prior art date
Application number
BR112018013381-7A
Other languages
English (en)
Inventor
Jung Park Tae
Jung Kim Hwa
Chul Shin Hyun
Original Assignee
Chung-Ang University Industry-Academic Cooperation Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chung-Ang University Industry-Academic Cooperation Foundation filed Critical Chung-Ang University Industry-Academic Cooperation Foundation
Publication of BR112018013381A2 publication Critical patent/BR112018013381A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

são fornecidos aqui um fragmento ligante a antígeno especificamente ligando a cfp 10 ou ag85b, que é um antígeno derivado de micobactéria, um polinucleotídeo codificando o mesmo, um vetor recombinante incluindo o polinucleotídeo, e uma célula hospedeira incluindo um vetor recombinante. quando o fragmento ligante a antígeno é usado, cfp-10 ou ag85b, que é um antígeno derivado de micobactéria, pode ser detectado com alta sensibilidade, e assim é possível desenvolver o fragmento ligante a antígeno como um kit capaz de rapidamente e precisamente detectar micobactéria.
BR112018013381-7A 2015-12-31 2016-12-30 anticorpo especificamente ligante a antígenos derivados de miobacteria ou fragmento ligante a antígeno do mesmo BR112018013381A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR10-2015-0191461 2015-12-31
KR20150191461 2015-12-31
KR1020160055153A KR101631054B1 (ko) 2015-12-31 2016-05-04 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
KR10-2016-0055153 2016-05-04
PCT/KR2016/015587 WO2017116212A1 (ko) 2015-12-31 2016-12-30 마이코박테리아 유래 항원에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편

Publications (1)

Publication Number Publication Date
BR112018013381A2 true BR112018013381A2 (pt) 2018-12-18

Family

ID=56355015

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018013381-7A BR112018013381A2 (pt) 2015-12-31 2016-12-30 anticorpo especificamente ligante a antígenos derivados de miobacteria ou fragmento ligante a antígeno do mesmo

Country Status (4)

Country Link
KR (1) KR101631054B1 (pt)
CN (1) CN109071638B (pt)
BR (1) BR112018013381A2 (pt)
WO (1) WO2017116212A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
WO2019117585A2 (ko) * 2017-12-11 2019-06-20 주식회사 딕스젠 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법
CN110172097B (zh) * 2019-05-22 2020-11-13 东方海洋(北京)医学研究院有限公司 一种抗结核分枝杆菌cfp-10蛋白的单克隆抗体及其应用
CA3164027A1 (en) * 2019-12-09 2021-06-17 Versiti Blood Research Institute Foundation Inc. Bcg car constructs and methods of their manufacture and use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050272104A1 (en) * 2004-06-07 2005-12-08 Chang Gung University Method for detection of Mycobacterium tuberculosis antigens in biological fluids
AU2008240181B2 (en) * 2007-04-12 2014-01-09 Jason Fisher Tuberculosis vaccine and method of using same
CN101985472B (zh) * 2010-10-12 2013-03-13 浙江大学 抗结核杆菌cfp-10单克隆抗体tbcd6及应用
BR112015000530A2 (pt) * 2012-07-10 2018-08-28 Transgene Sa vacina de antígeno micobacteriano.
CN102914520B (zh) * 2012-10-24 2015-02-25 上海大学 检测结核的表面等离子共振生物传感器,制备方法及其应用
KR101524109B1 (ko) * 2014-03-14 2015-06-02 충남대학교산학협력단 결핵균 특이항원에 대한 항체가 결합되어 있는 나노­바이오센서 및 이를 이용한 결핵균 검출진단법
CN104628833B (zh) * 2015-01-23 2016-03-23 中国疾病预防控制中心传染病预防控制所 一种结核感染细胞免疫检测抗原组合物及其应用
KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편

Also Published As

Publication number Publication date
CN109071638A (zh) 2018-12-21
CN109071638B (zh) 2022-01-25
WO2017116212A1 (ko) 2017-07-06
KR101631054B1 (ko) 2016-06-16

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B25A Requested transfer of rights approved

Owner name: DXGEN CORP. (KR)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]