CY1120194T1 - Χρησιμοποιηση παραγωγων χημικως τροποποιημενης ηπαρινης σε δρεπανοκυτταρικη νοσο - Google Patents
Χρησιμοποιηση παραγωγων χημικως τροποποιημενης ηπαρινης σε δρεπανοκυτταρικη νοσοInfo
- Publication number
- CY1120194T1 CY1120194T1 CY20181100482T CY181100482T CY1120194T1 CY 1120194 T1 CY1120194 T1 CY 1120194T1 CY 20181100482 T CY20181100482 T CY 20181100482T CY 181100482 T CY181100482 T CY 181100482T CY 1120194 T1 CY1120194 T1 CY 1120194T1
- Authority
- CY
- Cyprus
- Prior art keywords
- usrin
- producers
- surgery
- chemical modified
- factor
- Prior art date
Links
- 238000001356 surgical procedure Methods 0.000 title 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 208000007056 sickle cell anemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SE2011/051538 WO2013095215A1 (en) | 2011-12-19 | 2011-12-19 | Low anticoagulant heparins |
| PCT/SE2012/051429 WO2013095277A1 (en) | 2011-12-19 | 2012-12-19 | Use of chemically modified heparin derivates in sickle cell disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1120194T1 true CY1120194T1 (el) | 2018-12-12 |
Family
ID=48668926
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20181100482T CY1120194T1 (el) | 2011-12-19 | 2018-05-10 | Χρησιμοποιηση παραγωγων χημικως τροποποιημενης ηπαρινης σε δρεπανοκυτταρικη νοσο |
| CY20181100483T CY1120197T1 (el) | 2011-12-19 | 2018-05-10 | Ηπαρινες χαμηλης αντιπηκτικης δρασης |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20181100483T CY1120197T1 (el) | 2011-12-19 | 2018-05-10 | Ηπαρινες χαμηλης αντιπηκτικης δρασης |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US9480701B2 (enExample) |
| EP (2) | EP2794666B1 (enExample) |
| JP (2) | JP6703806B2 (enExample) |
| CN (1) | CN104053675B (enExample) |
| AU (1) | AU2012354226B2 (enExample) |
| BR (1) | BR112014014673B1 (enExample) |
| CA (2) | CA2856918C (enExample) |
| CY (2) | CY1120194T1 (enExample) |
| DK (2) | DK2794667T3 (enExample) |
| ES (2) | ES2668273T3 (enExample) |
| HR (2) | HRP20180725T1 (enExample) |
| HU (2) | HUE037555T2 (enExample) |
| IL (1) | IL232903A (enExample) |
| IN (1) | IN2014MN01056A (enExample) |
| MX (1) | MX358439B (enExample) |
| MY (1) | MY170069A (enExample) |
| NO (2) | NO2794667T3 (enExample) |
| PH (1) | PH12014501387B1 (enExample) |
| PL (2) | PL2794667T3 (enExample) |
| PT (2) | PT2794667T (enExample) |
| RS (2) | RS57214B1 (enExample) |
| SI (2) | SI2794666T1 (enExample) |
| SM (2) | SMT201800217T1 (enExample) |
| TN (2) | TN2014000236A1 (enExample) |
| WO (3) | WO2013095215A1 (enExample) |
| ZA (1) | ZA201403654B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013095215A1 (en) | 2011-12-19 | 2013-06-27 | Dilaforette Ab | Low anticoagulant heparins |
| DK2794665T3 (da) | 2011-12-19 | 2018-01-29 | Dilafor Ab | Ikke-antikoagulative glycosaminoglycaner omfattende disaccharid-gentagelsesenhed og medicinsk anvendelse deraf |
| GB2515315A (en) | 2013-06-19 | 2014-12-24 | Dilafor Ab | New Processes |
| EP2965764A1 (en) * | 2014-07-11 | 2016-01-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for treating vaso-occlusive crisis |
| EP3137099B1 (en) * | 2014-04-30 | 2019-09-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Dnase for use in treating vaso-occlusive crisis |
| CN105504097B (zh) * | 2015-12-30 | 2018-07-03 | 深圳市海普瑞药业集团股份有限公司 | 一种硫酸化肝素寡糖及其制备方法和应用 |
| CN108424474B (zh) * | 2017-02-15 | 2023-07-25 | 清华大学 | 去抗凝肝素衍生物及其用于炎症性肠病的治疗 |
| EP3773770B1 (en) * | 2018-04-13 | 2023-11-29 | University of Virginia Patent Foundation | Compositions and methods for preparing and using non-immunogenic fast annealing microporous annealed particle hydrogels |
| CN109481692A (zh) * | 2018-11-30 | 2019-03-19 | 东南大学 | 一种青蒿琥酯肝素衍生物及其药物组合物和应用 |
| WO2023192343A1 (en) * | 2022-03-29 | 2023-10-05 | The Penn State Research Foundation | Bioactive granular hydrogel scaffolds and use thereof |
| US12444880B2 (en) | 2022-05-05 | 2025-10-14 | Tego Innovations, Inc. | Magnetic power distribution assembly |
| WO2023239719A1 (en) | 2022-06-06 | 2023-12-14 | Ihp Therapeutics Inc. | Chemically modified heparin |
| EP4536248A4 (en) * | 2022-06-06 | 2026-02-11 | Ihp Therapeutics Inc | CHEMICALLY MODIFIED HEPARIN |
| CN115448994B (zh) * | 2022-09-28 | 2023-08-01 | 山东大学 | 一种可中和抗凝低分子量肝素及其制备方法和应用 |
| AU2023352919A1 (en) | 2022-09-29 | 2025-03-13 | Adora Life Science, Inc. | Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions |
| GB2625581A (en) * | 2022-12-21 | 2024-06-26 | Modus Therapeutics Ab | New medical use |
| WO2024170746A1 (en) | 2023-02-17 | 2024-08-22 | Modus Therapeutics Ab | New medical use of sevuparin in the treatment of endotoxemia |
| GB2627263A (en) * | 2023-02-17 | 2024-08-21 | Modus Therapeutics Ab | New medical use |
| CN116854838A (zh) * | 2023-06-30 | 2023-10-10 | 重庆望业药物研究有限公司 | 低分子多糖及其制备方法与应用 |
| GB202407366D0 (en) * | 2024-05-23 | 2024-07-10 | Glycos Biomedical Ltd | Preparation of medium molecular weight heparin |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1136620A (en) | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| FR2614026B1 (fr) | 1987-04-16 | 1992-04-17 | Sanofi Sa | Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques |
| ES2054975T3 (es) * | 1988-10-07 | 1994-08-16 | Hoechst Ag | Composiciones antimalaricas que emplean quinidina, artemisinina y sus derivados. |
| SE9002550D0 (sv) | 1990-08-01 | 1990-08-01 | Kabivitrum Ab | Heparinfragment |
| SE9003181D0 (sv) * | 1990-10-04 | 1990-10-04 | Kabivitrum Ab | Use of heparin fraction |
| US5250519A (en) * | 1991-03-29 | 1993-10-05 | Glycomed Incorporated | Non-anticoagulant heparin derivatives |
| US5280016A (en) * | 1991-03-29 | 1994-01-18 | Glycomed Incorporated | Non-anticoagulant heparin derivatives |
| JPH0532703A (ja) * | 1991-07-26 | 1993-02-09 | Terumo Corp | 低分子量ヘパリン誘導体の製造法 |
| WO1994008595A1 (en) | 1992-10-13 | 1994-04-28 | Virginia Commonwealth University | Use of non-anticoagulant heparin for treating ischemia/reperfusion injury |
| US5527785A (en) * | 1993-05-14 | 1996-06-18 | The Regents Of The University Of California | Selectin receptor modulating compositions |
| DE69623840D1 (de) * | 1995-03-31 | 2002-10-31 | Hamilton Civic Hospitals Res | Zusammensetzung zur Hemmung der Thromboseentstehung |
| US5993810A (en) | 1996-03-15 | 1999-11-30 | Lebovitz; Shamir Israel | Method of softening or ripening the cervix of a female mammal using collagenase |
| US5767269A (en) | 1996-10-01 | 1998-06-16 | Hamilton Civic Hospitals Research Development Inc. | Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics |
| NZ330603A (en) | 1996-10-15 | 2000-01-28 | Toray Industries | Hyaluronic acid derivatives used as cervical ripening agents |
| GB9711443D0 (en) | 1997-06-03 | 1997-07-30 | Leo Pharm Prod Ltd | Chemical suppositions |
| CA2310422A1 (en) * | 1997-11-20 | 1999-06-03 | Ikuo Yamashina | Low-molecular heparin modification and remedy for skin ulcer |
| US6596705B1 (en) * | 1998-02-09 | 2003-07-22 | The Regents Of The University Of California | Inhibition of L-selectin and P-selection mediated binding using heparin |
| WO1999043714A1 (fr) | 1998-02-26 | 1999-09-02 | Seikagaku Corporation | Nouveaux derives de polysaccharide, leur procede de production, et compositions medicinales contenant ces nouveaux derives comme principe actif |
| US6028061A (en) * | 1998-06-18 | 2000-02-22 | Children's Medical Center Corp | Angiogenesis inhibitors and use thereof |
| WO2000006608A1 (en) * | 1998-07-31 | 2000-02-10 | Seikagaku Corporation | Novel glycosaminoglycan and drug compositions containing the same |
| HK1045532A1 (zh) * | 1999-06-30 | 2002-11-29 | Hamilton Civic Hospitals Research Development, Inc. | 抑制与凝结有关凝结因子的肝素成份 |
| JP4897991B2 (ja) * | 1999-07-23 | 2012-03-14 | ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ | 超低分子量ヘパリン組成物 |
| IT1316986B1 (it) | 2000-01-25 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica. |
| JP4585072B2 (ja) * | 2000-02-29 | 2010-11-24 | 扶桑薬品工業株式会社 | ヘパリン解重合法、解重合ヘパリン、その誘導体および医薬組成物 |
| WO2002023190A2 (en) * | 2000-09-12 | 2002-03-21 | Massachusetts Institute Of Technology | Methods and products related to low molecular weight heparin |
| SE521676C2 (sv) | 2002-01-02 | 2003-11-25 | Dilafor Ab | Användning av glykosaminoglykaner för prevention och behandling av värksvaghet vid fullgången graviditet |
| AU2003230985A1 (en) | 2002-04-18 | 2003-11-03 | Stephen H. Embury | Method and composition for preventing pain in sickle cell patients |
| US8071569B2 (en) * | 2002-09-20 | 2011-12-06 | Mousa Shaker A | Oxidized heparin fractions and their use in inhibiting angiogenesis |
| EP1582531A1 (en) * | 2004-03-24 | 2005-10-05 | Aventis Pharma S.A. | Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products |
| US8383154B2 (en) * | 2004-05-11 | 2013-02-26 | Egalet A/S | Swellable dosage form comprising gellan gum |
| US20060040896A1 (en) | 2004-08-18 | 2006-02-23 | Paringenix, Inc. | Method and medicament for anticoagulation using a sulfated polysaccharide with enhanced anti-inflammatory activity |
| US7741311B2 (en) * | 2005-01-03 | 2010-06-22 | Shaker Mousa | Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing |
| BRPI0613677A2 (pt) | 2005-07-22 | 2011-01-25 | Trf Pharma Inc | método para tratar doença de célula falsiforme e sequelas da doença de célula falsiforme |
| US20070021378A1 (en) * | 2005-07-22 | 2007-01-25 | The Regents Of The University Of California | Heparin compositions and selectin inhibition |
| AU2007267561B2 (en) * | 2006-05-25 | 2012-05-17 | Momenta Pharmaceuticals, Inc. | Low molecular weight heparin composition and uses thereof |
| WO2009007224A1 (en) * | 2007-07-10 | 2009-01-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Low molecular weight heparin derivatives having neuroprotective activity |
| US8592393B2 (en) * | 2007-11-02 | 2013-11-26 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
| US8569262B2 (en) | 2007-11-02 | 2013-10-29 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
| EP2205642B1 (en) * | 2007-11-02 | 2016-01-27 | Momenta Pharmaceuticals, Inc. | Non-anticoagulant polysaccharide compositions |
| US8445436B2 (en) | 2007-12-03 | 2013-05-21 | Florida State University Research Foundation, Inc. | Oxytocin and melatonin compositions and associated methods for inducing labor |
| JP5758797B2 (ja) * | 2008-04-04 | 2015-08-05 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法 |
| WO2010009492A1 (en) * | 2008-07-25 | 2010-01-28 | Alphapharm Pty Ltd | ATOVAQUONE WITH A PARTICLE SIZE DIAMETER RANGE (D90) OF GREATER THAN 3 μM TO ABOUT 10 μM |
| DK2419736T3 (da) | 2009-04-16 | 2014-04-22 | Momenta Pharmaceuticals Inc | Fremgangsmåder til vurdering af aktivitet af en polysaccharidsammensætning |
| WO2011000032A1 (en) * | 2009-06-30 | 2011-01-06 | Walter And Eliza Hall Institute Of Medical Research | Sulfated polysaccharides having antiplasmodial activity and methods and products for identifying antiplasmodial activity |
| DK2794665T3 (da) | 2011-12-19 | 2018-01-29 | Dilafor Ab | Ikke-antikoagulative glycosaminoglycaner omfattende disaccharid-gentagelsesenhed og medicinsk anvendelse deraf |
| WO2013095215A1 (en) | 2011-12-19 | 2013-06-27 | Dilaforette Ab | Low anticoagulant heparins |
| CN104203256B (zh) | 2012-03-26 | 2017-11-24 | 迪乐方有限责任公司 | 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗 |
| NZ631279A (en) | 2012-03-26 | 2016-06-24 | Dilafor Ab | Method for treatment of labor arrest |
-
2011
- 2011-12-19 WO PCT/SE2011/051538 patent/WO2013095215A1/en not_active Ceased
-
2012
- 2012-12-19 MY MYPI2014001796A patent/MY170069A/en unknown
- 2012-12-19 PT PT128609385T patent/PT2794667T/pt unknown
- 2012-12-19 HU HUE12860938A patent/HUE037555T2/hu unknown
- 2012-12-19 RS RS20180574A patent/RS57214B1/sr unknown
- 2012-12-19 ES ES12859384.5T patent/ES2668273T3/es active Active
- 2012-12-19 CN CN201280062042.7A patent/CN104053675B/zh active Active
- 2012-12-19 PL PL12860938T patent/PL2794667T3/pl unknown
- 2012-12-19 PL PL12859384T patent/PL2794666T3/pl unknown
- 2012-12-19 HR HRP20180725TT patent/HRP20180725T1/hr unknown
- 2012-12-19 DK DK12860938.5T patent/DK2794667T3/en active
- 2012-12-19 DK DK12859384.5T patent/DK2794666T3/en active
- 2012-12-19 AU AU2012354226A patent/AU2012354226B2/en active Active
- 2012-12-19 EP EP12859384.5A patent/EP2794666B1/en active Active
- 2012-12-19 HU HUE12859384A patent/HUE037554T2/hu unknown
- 2012-12-19 US US14/366,570 patent/US9480701B2/en active Active
- 2012-12-19 PT PT128593845T patent/PT2794666T/pt unknown
- 2012-12-19 IN IN1056MUN2014 patent/IN2014MN01056A/en unknown
- 2012-12-19 NO NO12860938A patent/NO2794667T3/no unknown
- 2012-12-19 MX MX2014006956A patent/MX358439B/es active IP Right Grant
- 2012-12-19 WO PCT/SE2012/051429 patent/WO2013095277A1/en not_active Ceased
- 2012-12-19 WO PCT/SE2012/051428 patent/WO2013095276A1/en not_active Ceased
- 2012-12-19 SI SI201231282T patent/SI2794666T1/en unknown
- 2012-12-19 SI SI201231283T patent/SI2794667T1/en unknown
- 2012-12-19 EP EP12860938.5A patent/EP2794667B1/en active Active
- 2012-12-19 SM SM20180217T patent/SMT201800217T1/it unknown
- 2012-12-19 US US14/366,603 patent/US9480702B2/en active Active
- 2012-12-19 CA CA2856918A patent/CA2856918C/en not_active Expired - Fee Related
- 2012-12-19 BR BR112014014673-0A patent/BR112014014673B1/pt active IP Right Grant
- 2012-12-19 HR HRP20180726TT patent/HRP20180726T1/hr unknown
- 2012-12-19 CA CA2856477A patent/CA2856477C/en active Active
- 2012-12-19 JP JP2014547145A patent/JP6703806B2/ja active Active
- 2012-12-19 SM SM20180218T patent/SMT201800218T1/it unknown
- 2012-12-19 NO NO12859384A patent/NO2794666T3/no unknown
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2014
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