CY1119899T1 - Μη αντιπηκτικες γλυκοζαμιnoγλυκανες που εμπεριεχουν επαναλαμβανομενη μοναδα δισακχαριτη και η ιατρικη τους χρηση - Google Patents

Μη αντιπηκτικες γλυκοζαμιnoγλυκανες που εμπεριεχουν επαναλαμβανομενη μοναδα δισακχαριτη και η ιατρικη τους χρηση

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Publication number
CY1119899T1
CY1119899T1 CY20181100162T CY181100162T CY1119899T1 CY 1119899 T1 CY1119899 T1 CY 1119899T1 CY 20181100162 T CY20181100162 T CY 20181100162T CY 181100162 T CY181100162 T CY 181100162T CY 1119899 T1 CY1119899 T1 CY 1119899T1
Authority
CY
Cyprus
Prior art keywords
glucosaminoglycans
recoverable
underground
medical use
disc unit
Prior art date
Application number
CY20181100162T
Other languages
English (en)
Inventor
Hans-Peter Ekre
Per-Olov ERIKSSON
Ulf Lindahl
Erik Holmer
Original Assignee
Dilafor Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48668970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119899(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dilafor Ab filed Critical Dilafor Ab
Publication of CY1119899T1 publication Critical patent/CY1119899T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Η παρούσα εφεύρεση αφορά χημικώς τροποποιημένη γλυκοζαμινογλυκάνη με δραστικότητα κατά του παράγοντα II μικρότερη από 10 IU/mg, με δραστικότητα κατά του παράγοντα Xa μικρότερη από 10 IU/mg και με μέσο μοριακό βάρος (Mw, μέσο κατά βάρος) από περίπου 4,6 έως 6,9 kDa. Αποκαλύπτεται επίσης μέθοδος παρασκευής της τροποποιημένης γλυκοζαμινογλυκάνης και οι ιατρικές της χρήσεις.
CY20181100162T 2011-12-19 2018-02-09 Μη αντιπηκτικες γλυκοζαμιnoγλυκανες που εμπεριεχουν επαναλαμβανομενη μοναδα δισακχαριτη και η ιατρικη τους χρηση CY1119899T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161577223P 2011-12-19 2011-12-19
PCT/SE2012/051433 WO2013095279A1 (en) 2011-12-19 2012-12-19 Non anti-coagulative glycosaminoglycans comprising repeating disaccharide unit and their medical use

Publications (1)

Publication Number Publication Date
CY1119899T1 true CY1119899T1 (el) 2018-06-27

Family

ID=48668970

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20181100162T CY1119899T1 (el) 2011-12-19 2018-02-09 Μη αντιπηκτικες γλυκοζαμιnoγλυκανες που εμπεριεχουν επαναλαμβανομενη μοναδα δισακχαριτη και η ιατρικη τους χρηση

Country Status (28)

Country Link
US (1) US9475888B2 (el)
EP (1) EP2794665B1 (el)
JP (2) JP6543467B2 (el)
KR (1) KR102135485B1 (el)
CN (1) CN104144950B (el)
AU (1) AU2012354229B2 (el)
BR (1) BR112014014454B1 (el)
CA (1) CA2856492C (el)
CL (1) CL2014001651A1 (el)
CO (1) CO7061069A2 (el)
CY (1) CY1119899T1 (el)
DK (1) DK2794665T3 (el)
ES (1) ES2656613T3 (el)
HK (1) HK1202883A1 (el)
HR (1) HRP20180124T1 (el)
HU (1) HUE036523T2 (el)
IL (1) IL232905A (el)
LT (1) LT2794665T (el)
ME (1) ME02994B (el)
MX (1) MX351104B (el)
NO (1) NO2904345T3 (el)
PL (1) PL2794665T3 (el)
PT (1) PT2794665T (el)
RS (1) RS56874B1 (el)
RU (1) RU2617764C2 (el)
SI (1) SI2794665T1 (el)
WO (1) WO2013095279A1 (el)
ZA (1) ZA201403640B (el)

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MY185108A (en) * 2012-03-26 2021-04-30 Dilafor Ab Method for treatment of labor arrest
CA2868403A1 (en) * 2012-05-08 2013-11-14 Dilafor Ab Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent
GB2515315A (en) * 2013-06-19 2014-12-24 Dilafor Ab New Processes
CN103788222B (zh) * 2014-01-08 2016-08-31 中国科学院昆明植物研究所 Fuc3S4S取代的低聚糖胺聚糖及其制备方法
KR20170013255A (ko) * 2014-04-30 2017-02-06 에이전시 포 사이언스, 테크놀로지 앤드 리서치 헤파란 설페이트
CN108424474B (zh) * 2017-02-15 2023-07-25 清华大学 去抗凝肝素衍生物及其用于炎症性肠病的治疗
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Also Published As

Publication number Publication date
ME02994B (me) 2018-10-20
MX2014007122A (es) 2015-03-05
CA2856492C (en) 2017-01-10
HRP20180124T1 (hr) 2018-02-23
US20150011505A1 (en) 2015-01-08
HUE036523T2 (hu) 2018-07-30
KR20140113652A (ko) 2014-09-24
LT2794665T (lt) 2017-12-27
MX351104B (es) 2017-10-02
EP2794665A1 (en) 2014-10-29
JP6543467B2 (ja) 2019-07-10
CL2014001651A1 (es) 2014-10-10
RS56874B1 (sr) 2018-04-30
CN104144950B (zh) 2017-09-05
JP2018111825A (ja) 2018-07-19
BR112014014454B1 (pt) 2021-03-09
RU2014129816A (ru) 2016-02-20
CA2856492A1 (en) 2013-06-27
PT2794665T (pt) 2018-01-24
ES2656613T3 (es) 2018-02-27
NO2904345T3 (el) 2018-07-21
RU2617764C2 (ru) 2017-04-26
AU2012354229A1 (en) 2014-06-05
KR102135485B1 (ko) 2020-07-17
CN104144950A (zh) 2014-11-12
ZA201403640B (en) 2017-06-28
AU2012354229B2 (en) 2016-12-01
CO7061069A2 (es) 2014-09-19
WO2013095279A1 (en) 2013-06-27
IL232905A (en) 2017-02-28
HK1202883A1 (en) 2015-10-09
IL232905A0 (en) 2014-07-31
EP2794665A4 (en) 2015-08-26
DK2794665T3 (da) 2018-01-29
PL2794665T3 (pl) 2018-04-30
JP2015500388A (ja) 2015-01-05
EP2794665B1 (en) 2017-11-22
BR112014014454A2 (pt) 2017-06-13
US9475888B2 (en) 2016-10-25
SI2794665T1 (en) 2018-03-30

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