CY1114960T1 - Συνθεσεις που περιλαμβανουν τραμαδολη και σελεκοξιμπη στην θεραπεια πονου - Google Patents

Συνθεσεις που περιλαμβανουν τραμαδολη και σελεκοξιμπη στην θεραπεια πονου

Info

Publication number
CY1114960T1
CY1114960T1 CY20141100195T CY141100195T CY1114960T1 CY 1114960 T1 CY1114960 T1 CY 1114960T1 CY 20141100195 T CY20141100195 T CY 20141100195T CY 141100195 T CY141100195 T CY 141100195T CY 1114960 T1 CY1114960 T1 CY 1114960T1
Authority
CY
Cyprus
Prior art keywords
tramadoli
sellekoxibe
compositions including
pain treatment
treatment
Prior art date
Application number
CY20141100195T
Other languages
English (en)
Inventor
Salido Enrique Portillo
CES Sebastià VIDELA
Original Assignee
Laboratorios Del Dr. Esteve, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41566149&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1114960(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratorios Del Dr. Esteve, S.A. filed Critical Laboratorios Del Dr. Esteve, S.A.
Publication of CY1114960T1 publication Critical patent/CY1114960T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Η παρούσα εφεύρεση αφορά σε φαρμακευτικές συνθέσεις που περιλαμβάνουν τραμαδόλη και σελεκοξίμπη και χρήσεις αυτών ως φάρμακα ή αναλγητικά, ειδικότερα για την θεραπεία σοβαρού έως μετρίου πόνου με φλεγμονώδες συστατικό.
CY20141100195T 2009-10-16 2014-03-10 Συνθεσεις που περιλαμβανουν τραμαδολη και σελεκοξιμπη στην θεραπεια πονου CY1114960T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09384004A EP2311446A1 (en) 2009-10-16 2009-10-16 Compositions comprising Tramadol and Celecoxib in the treatment of pain
EP10765762.9A EP2488170B1 (en) 2009-10-16 2010-10-15 Compositions comprising tramadol and celecoxib in the treatment of pain

Publications (1)

Publication Number Publication Date
CY1114960T1 true CY1114960T1 (el) 2016-12-14

Family

ID=41566149

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20141100195T CY1114960T1 (el) 2009-10-16 2014-03-10 Συνθεσεις που περιλαμβανουν τραμαδολη και σελεκοξιμπη στην θεραπεια πονου

Country Status (34)

Country Link
US (3) US8569271B2 (el)
EP (3) EP2311446A1 (el)
JP (2) JP5579858B2 (el)
KR (1) KR101688996B1 (el)
CN (2) CN102573824A (el)
AR (1) AR078653A1 (el)
AU (1) AU2010306114B2 (el)
BR (1) BR112012005044B8 (el)
CA (1) CA2771651C (el)
CO (1) CO6511249A2 (el)
CY (1) CY1114960T1 (el)
DK (1) DK2488170T3 (el)
EC (1) ECSP12011735A (el)
ES (1) ES2450615T3 (el)
HK (1) HK1173379A1 (el)
HR (1) HRP20140157T1 (el)
IL (1) IL218096A (el)
IN (1) IN2012DN01434A (el)
MA (1) MA33743B1 (el)
MX (1) MX2012003051A (el)
MY (1) MY156275A (el)
NZ (1) NZ598361A (el)
PL (1) PL2488170T3 (el)
PT (1) PT2488170E (el)
RS (1) RS53202B (el)
RU (2) RU2707752C2 (el)
SG (1) SG178833A1 (el)
SI (1) SI2488170T1 (el)
SM (1) SMT201400035B (el)
TN (1) TN2012000059A1 (el)
TW (1) TWI466668B (el)
UA (1) UA108213C2 (el)
WO (1) WO2011045075A1 (el)
ZA (1) ZA201202151B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2177215A1 (en) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
US8746719B2 (en) 2010-08-03 2014-06-10 Polaris Industries Inc. Side-by-side vehicle
MX346312B (es) * 2011-04-05 2017-03-15 Optosolve Res & Dev Ltd Tratamientos oftalmicos.
US9173863B2 (en) 2012-02-06 2015-11-03 Innovative Med Concepts, LLC Antiviral compound and COX-2 inhibitor combination therapy for functional somatic syndromes, including combination of famciclovir and celecoxib
WO2016116942A1 (en) 2015-01-20 2016-07-28 Anlon Chemical Research Organization Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin
WO2016191744A1 (en) * 2015-05-28 2016-12-01 Dr. Reddy's Laboratories Ltd. Oral composition of celecoxib for treatment of pain
KR101710792B1 (ko) * 2015-07-14 2017-02-28 주식회사 유영제약 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물
MX2016006464A (es) * 2016-05-18 2017-11-17 Laboratorios Liomont S A De C V Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor.
RU2745196C2 (ru) * 2016-05-27 2021-03-22 Др. Редди'С Лабораторис Лтд. Пероральная композиция целекоксиба для лечения боли
US20200323780A1 (en) * 2017-04-03 2020-10-15 Kims Healthcare Co., Ltd. Bilayer combination tablet for oral administration containing tramadol and celecoxib
WO2018186650A2 (ko) * 2017-04-03 2018-10-11 주식회사 킴스헬스케어 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제
KR102631399B1 (ko) 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
KR20220008301A (ko) * 2019-05-14 2022-01-20 에스테베 파마슈티칼스 에스에이 트라마돌의 남용 경향을 감소시키면서 통증을 치료하기 위한 트라마돌과 세레콕시브의 공-결정의 용도
CN112007024A (zh) * 2019-05-28 2020-12-01 江苏恒瑞医药股份有限公司 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516803A (en) 1991-10-30 1996-05-14 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
AU661723B2 (en) 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
RS49982B (sr) * 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
JP2002538176A (ja) * 1999-03-01 2002-11-12 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド トラマドール物質および選択的cox−2阻害薬を含んで成る組成物
DE19927688A1 (de) 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
AU2003208485B2 (en) * 2002-02-19 2009-05-28 Adcock Ingram Limited Pharmaceutical combinations of COX-2 inhibitors and opiates
US20080031950A1 (en) * 2007-04-27 2008-02-07 Nectid Inc. Novel anelgesic combination
CA2771665C (en) 2009-10-16 2015-10-06 Laboratorios Del Dr. Esteve, S.A. Co-crystals of tramadol and coxibs
EP2392319A1 (en) 2010-06-04 2011-12-07 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical compositions of co-crystals of tramadol and coxibs

Also Published As

Publication number Publication date
EP2737898A1 (en) 2014-06-04
BR112012005044B8 (pt) 2021-05-25
UA108213C2 (uk) 2015-04-10
HK1173379A1 (en) 2013-05-16
SI2488170T1 (sl) 2014-04-30
RU2016125895A3 (el) 2018-12-05
SG178833A1 (en) 2012-05-30
PL2488170T3 (pl) 2014-05-30
BR112012005044B1 (pt) 2020-12-15
KR101688996B1 (ko) 2016-12-22
EP2311446A1 (en) 2011-04-20
AR078653A1 (es) 2011-11-23
TW201114418A (en) 2011-05-01
US8569271B2 (en) 2013-10-29
EP2488170B1 (en) 2014-01-22
CN107050006A (zh) 2017-08-18
RU2707752C2 (ru) 2019-11-29
CA2771651C (en) 2016-08-23
AU2010306114B2 (en) 2015-07-23
BR112012005044A2 (pt) 2016-05-03
WO2011045075A1 (en) 2011-04-21
DK2488170T3 (en) 2014-03-03
MA33743B1 (fr) 2012-11-01
MY156275A (en) 2016-01-29
ZA201202151B (en) 2012-11-28
ES2450615T3 (es) 2014-03-25
MX2012003051A (es) 2012-05-29
CO6511249A2 (es) 2012-08-31
SMT201400035B (it) 2014-05-07
IL218096A0 (en) 2012-04-30
US20140024622A1 (en) 2014-01-23
JP2013507408A (ja) 2013-03-04
ECSP12011735A (es) 2012-05-30
JP2014221797A (ja) 2014-11-27
HRP20140157T1 (hr) 2014-03-28
EP2488170A1 (en) 2012-08-22
US20120172341A1 (en) 2012-07-05
KR20120089287A (ko) 2012-08-09
TN2012000059A1 (en) 2013-09-19
RU2012120087A (ru) 2013-11-27
CN102573824A (zh) 2012-07-11
JP5579858B2 (ja) 2014-08-27
IL218096A (en) 2015-02-26
IN2012DN01434A (el) 2015-06-05
AU2010306114A1 (en) 2012-03-15
PT2488170E (pt) 2014-03-11
RS53202B (en) 2014-06-30
CA2771651A1 (en) 2011-04-11
RU2016125895A (ru) 2018-12-05
TWI466668B (zh) 2015-01-01
US20150150889A1 (en) 2015-06-04
NZ598361A (en) 2014-01-31

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