SMT201800217T1 - Eparine ad effetto anticoagulante ridotto - Google Patents

Eparine ad effetto anticoagulante ridotto

Info

Publication number
SMT201800217T1
SMT201800217T1 SM20180217T SMT201800217T SMT201800217T1 SM T201800217 T1 SMT201800217 T1 SM T201800217T1 SM 20180217 T SM20180217 T SM 20180217T SM T201800217 T SMT201800217 T SM T201800217T SM T201800217 T1 SMT201800217 T1 SM T201800217T1
Authority
SM
San Marino
Prior art keywords
low anticoagulant
anticoagulant heparins
heparins
low
anticoagulant
Prior art date
Application number
SM20180217T
Other languages
English (en)
Italian (it)
Inventor
Hans-Peter Ekre
Per-Olov Eriksson
Ulf Lindahl
Erik Holmer
Anna Leitgeb
Mats Wahlgren
Stefania Tidia
Lino Liverani
Original Assignee
Modus Therapeutics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Modus Therapeutics Ab filed Critical Modus Therapeutics Ab
Publication of SMT201800217T1 publication Critical patent/SMT201800217T1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078Degradation products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM20180217T 2011-12-19 2012-12-19 Eparine ad effetto anticoagulante ridotto SMT201800217T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/SE2011/051538 WO2013095215A1 (en) 2011-12-19 2011-12-19 Low anticoagulant heparins
PCT/SE2012/051428 WO2013095276A1 (en) 2011-12-19 2012-12-19 Low anticoagulant heparins
EP12860938.5A EP2794667B1 (en) 2011-12-19 2012-12-19 Low anticoagulant heparins

Publications (1)

Publication Number Publication Date
SMT201800217T1 true SMT201800217T1 (it) 2018-05-02

Family

ID=48668926

Family Applications (2)

Application Number Title Priority Date Filing Date
SM20180217T SMT201800217T1 (it) 2011-12-19 2012-12-19 Eparine ad effetto anticoagulante ridotto
SM20180218T SMT201800218T1 (it) 2011-12-19 2012-12-19 Uso di derivati di eparina chimicamente modificata nell'anemia falciforme

Family Applications After (1)

Application Number Title Priority Date Filing Date
SM20180218T SMT201800218T1 (it) 2011-12-19 2012-12-19 Uso di derivati di eparina chimicamente modificata nell'anemia falciforme

Country Status (26)

Country Link
US (2) US9480702B2 (enExample)
EP (2) EP2794666B1 (enExample)
JP (2) JP6703806B2 (enExample)
CN (1) CN104053675B (enExample)
AU (1) AU2012354226B2 (enExample)
BR (1) BR112014014673B1 (enExample)
CA (2) CA2856918C (enExample)
CY (2) CY1120197T1 (enExample)
DK (2) DK2794667T3 (enExample)
ES (2) ES2669055T3 (enExample)
HR (2) HRP20180725T1 (enExample)
HU (2) HUE037555T2 (enExample)
IL (1) IL232903A (enExample)
IN (1) IN2014MN01056A (enExample)
MX (1) MX358439B (enExample)
MY (1) MY170069A (enExample)
NO (2) NO2794667T3 (enExample)
PH (1) PH12014501387A1 (enExample)
PL (2) PL2794666T3 (enExample)
PT (2) PT2794667T (enExample)
RS (2) RS57213B1 (enExample)
SI (2) SI2794667T1 (enExample)
SM (2) SMT201800217T1 (enExample)
TN (2) TN2014000237A1 (enExample)
WO (3) WO2013095215A1 (enExample)
ZA (1) ZA201403654B (enExample)

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JP6543467B2 (ja) 2011-12-19 2019-07-10 ディラホア アクチエボラゲット 二糖繰り返し単位を含んでいる非抗凝固グリコサミノグリカンおよびそれらの医療用途
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US20170049862A1 (en) * 2014-04-30 2017-02-23 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for treating vaso-occlusive crisis
EP2965764A1 (en) * 2014-07-11 2016-01-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treating vaso-occlusive crisis
CN105504097B (zh) * 2015-12-30 2018-07-03 深圳市海普瑞药业集团股份有限公司 一种硫酸化肝素寡糖及其制备方法和应用
CN108424474B (zh) * 2017-02-15 2023-07-25 清华大学 去抗凝肝素衍生物及其用于炎症性肠病的治疗
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JP6543467B2 (ja) 2011-12-19 2019-07-10 ディラホア アクチエボラゲット 二糖繰り返し単位を含んでいる非抗凝固グリコサミノグリカンおよびそれらの医療用途
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Also Published As

Publication number Publication date
IL232903A (en) 2017-02-28
JP2015500387A (ja) 2015-01-05
BR112014014673A8 (pt) 2017-07-04
AU2012354226A1 (en) 2014-06-05
MX358439B (es) 2018-08-21
HUE037554T2 (hu) 2018-09-28
EP2794667A1 (en) 2014-10-29
IL232903A0 (en) 2014-07-31
WO2013095276A1 (en) 2013-06-27
SI2794667T1 (en) 2018-06-29
CY1120197T1 (el) 2018-12-12
HK1199893A1 (en) 2015-07-24
HRP20180725T1 (hr) 2018-06-29
US9480701B2 (en) 2016-11-01
NZ625096A (en) 2016-07-29
IN2014MN01056A (enExample) 2015-05-01
WO2013095215A1 (en) 2013-06-27
SMT201800218T1 (it) 2018-05-02
PT2794667T (pt) 2018-05-16
PL2794666T3 (pl) 2018-08-31
PH12014501387B1 (en) 2014-09-22
CA2856918A1 (en) 2013-06-27
EP2794666A1 (en) 2014-10-29
US20140364369A1 (en) 2014-12-11
TN2014000236A1 (en) 2015-09-30
PH12014501387A1 (en) 2014-09-22
CN104053675B (zh) 2016-10-12
AU2012354226B2 (en) 2017-01-12
MX2014006956A (es) 2014-10-17
DK2794666T3 (en) 2018-04-23
EP2794666B1 (en) 2018-02-21
JP2018154848A (ja) 2018-10-04
ES2668273T3 (es) 2018-05-17
ES2669055T3 (es) 2018-05-23
NO2794667T3 (enExample) 2018-07-21
BR112014014673A2 (pt) 2017-06-13
BR112014014673B1 (pt) 2021-02-17
RS57213B1 (sr) 2018-07-31
CA2856477A1 (en) 2013-06-27
CA2856918C (en) 2017-07-04
ZA201403654B (en) 2017-08-30
MY170069A (en) 2019-07-03
HUE037555T2 (hu) 2018-09-28
TN2014000237A1 (en) 2015-09-30
DK2794667T3 (en) 2018-04-23
JP6703806B2 (ja) 2020-06-03
PL2794667T3 (pl) 2018-09-28
EP2794667A4 (en) 2015-07-22
CN104053675A (zh) 2014-09-17
US9480702B2 (en) 2016-11-01
EP2794667B1 (en) 2018-02-21
EP2794666A4 (en) 2015-07-22
CY1120194T1 (el) 2018-12-12
CA2856477C (en) 2017-06-27
WO2013095277A1 (en) 2013-06-27
RS57214B1 (sr) 2018-07-31
PT2794666T (pt) 2018-05-09
US20150031638A1 (en) 2015-01-29
HK1200471A1 (en) 2015-08-07
HRP20180726T1 (hr) 2018-06-15
SI2794666T1 (en) 2018-06-29
NO2794666T3 (enExample) 2018-07-21

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