CY1120146T1 - Ενεσιμη συνθεση η οποια περιλαμβανει δεοξυχολικο νατριο - Google Patents
Ενεσιμη συνθεση η οποια περιλαμβανει δεοξυχολικο νατριοInfo
- Publication number
- CY1120146T1 CY1120146T1 CY20181100197T CY181100197T CY1120146T1 CY 1120146 T1 CY1120146 T1 CY 1120146T1 CY 20181100197 T CY20181100197 T CY 20181100197T CY 181100197 T CY181100197 T CY 181100197T CY 1120146 T1 CY1120146 T1 CY 1120146T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmacologically active
- dioxyl
- sodium
- composition containing
- ingredient composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 239000004615 ingredient Substances 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 239000003599 detergent Substances 0.000 abstract 3
- 238000001356 surgical procedure Methods 0.000 abstract 2
- 208000035484 Cellulite Diseases 0.000 abstract 1
- 206010049287 Lipodystrophy acquired Diseases 0.000 abstract 1
- 206010049752 Peau d'orange Diseases 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 230000036232 cellulite Effects 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 210000000744 eyelid Anatomy 0.000 abstract 1
- 208000006132 lipodystrophy Diseases 0.000 abstract 1
- 238000007443 liposuction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Medicinal Preparation (AREA)
- Edible Oils And Fats (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Συνθέσεις και μέθοδοι χρήσιμες στη μη-χειρουργική αφαίρεση εντοπισμένων εναποθέσεων λίπους σε ασθενείς οι οποίοι την έχουν ανάγκη χρησιμοποιώντας φαρμακολογικώς δραστικά απορρυπαντικά γνωστοποιούνται. Οι συνθέσεις φαρμακολογικώς δραστικών απορρυπαντικών μπορεί επιπροσθέτως να περιλαμβάνουν αντι-φλεγμονώδεις παράγοντες, αναλγητικά, παράγοντες διασποράς και φαρμακευτικώς αποδεκτά έκδοχα αλλά δεν περιέχουν φωσφατιδυλοχολίνη. Οι συνθέσεις φαρμακολογικώς δραστικών απορρυπαντικών είναι χρήσιμες για αντιμετώπιση εντοπισμένων συσσωρεύσεων λίπους περιλαμβάνοντας κήλη λίπους στο κάτω βλέφαρο, λιποδυστροφία και εναποθέσεις λίπους οι οποίες συνδέονται με κυτταρίτιδα και δεν απαιτούν χειρουργικές διαδικασίες όπως λιποαναρρόφηση.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57287904P | 2004-05-19 | 2004-05-19 | |
EP05722895A EP1758590B1 (en) | 2004-05-19 | 2005-02-08 | Use of a detergent for the non-surgical removal of fat |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120146T1 true CY1120146T1 (el) | 2018-12-12 |
Family
ID=34961536
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111101007T CY1111974T1 (el) | 2004-05-19 | 2011-10-25 | Χρηση ενος απορρυπαντικου για τη μη-χειρουργικη αφαιρεση λιπους |
CY20111101044T CY1112204T1 (el) | 2004-05-19 | 2011-10-31 | Μεθοδοι και σχετικες συνθεσεις για μειωση του λιπους |
CY20181100197T CY1120146T1 (el) | 2004-05-19 | 2018-02-21 | Ενεσιμη συνθεση η οποια περιλαμβανει δεοξυχολικο νατριο |
CY2018008C CY2018008I1 (el) | 2004-05-19 | 2018-03-13 | Χρηση ενος απορρυπαντικου για τη μη-χειρουργικη αφαιρεση λιπους |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111101007T CY1111974T1 (el) | 2004-05-19 | 2011-10-25 | Χρηση ενος απορρυπαντικου για τη μη-χειρουργικη αφαιρεση λιπους |
CY20111101044T CY1112204T1 (el) | 2004-05-19 | 2011-10-31 | Μεθοδοι και σχετικες συνθεσεις για μειωση του λιπους |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY2018008C CY2018008I1 (el) | 2004-05-19 | 2018-03-13 | Χρηση ενος απορρυπαντικου για τη μη-χειρουργικη αφαιρεση λιπους |
Country Status (25)
Country | Link |
---|---|
US (3) | US7622130B2 (el) |
EP (8) | EP1758590B1 (el) |
JP (2) | JP5060295B2 (el) |
KR (1) | KR101217497B1 (el) |
CN (2) | CN101018553B (el) |
AT (2) | ATE521355T1 (el) |
AU (1) | AU2005245002C1 (el) |
CA (1) | CA2567298C (el) |
CY (4) | CY1111974T1 (el) |
DK (5) | DK1758590T3 (el) |
ES (5) | ES2372499T3 (el) |
FI (1) | FI3692995T3 (el) |
FR (2) | FR20C1048I2 (el) |
HK (2) | HK1099521A1 (el) |
HU (5) | HUE038247T2 (el) |
IL (2) | IL179008A (el) |
LT (3) | LT2422789T (el) |
MX (1) | MXPA06013437A (el) |
NL (1) | NL301229I2 (el) |
NZ (2) | NZ586818A (el) |
PL (4) | PL1758590T3 (el) |
PT (5) | PT2422789T (el) |
SI (4) | SI1758590T1 (el) |
TR (1) | TR201802446T4 (el) |
WO (2) | WO2005117900A1 (el) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1758590T3 (da) * | 2004-05-19 | 2011-11-21 | Los Angeles Biomed Res Inst | Anvendelse af et detergent til ikke-kirurgisk fjernelse af fedt |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
US20060074057A1 (en) * | 2004-10-04 | 2006-04-06 | Eric Marchewitz | Use of chenodeoxycholic acid for reducing adipose tissue |
JP4646669B2 (ja) * | 2005-03-30 | 2011-03-09 | キヤノン株式会社 | 吐出用液体、吐出方法、液滴化方法、カートリッジ及び吐出装置 |
US20060222695A1 (en) * | 2005-04-01 | 2006-10-05 | Filiberto Zadini | Deoxycholic acid liposome-based dermatological topical preparation |
US20070071706A1 (en) * | 2005-09-28 | 2007-03-29 | Filiberto Zadini | Lipodissolving dermatological topical preparation |
US20090035348A1 (en) * | 2005-11-22 | 2009-02-05 | Z & Z Medical Holdings, Inc. | Dissolution of arterial plaque |
US8304383B2 (en) | 2005-11-22 | 2012-11-06 | Atheronova Operations, Inc. | Dissolution of arterial plaque |
US7676604B2 (en) * | 2005-11-22 | 2010-03-09 | Intel Corporation | Task context direct indexing in a protocol engine |
US20110082124A1 (en) * | 2006-02-23 | 2011-04-07 | Kythera Biopharmaceuticals, Inc. | Detergent compositions for treatment of lipomas and other conditions |
US20090233885A1 (en) * | 2006-07-14 | 2009-09-17 | Duncan Diane I | Compositions and Methods for Fat Reduction |
US20100063006A1 (en) * | 2006-11-22 | 2010-03-11 | American Network Of Lipolysis, Llc | Compositions and methods to reduce fat and retract skin |
DE102007015701A1 (de) * | 2007-03-19 | 2008-09-25 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung |
US8057381B2 (en) * | 2007-04-16 | 2011-11-15 | Allen Iii William F | Method and implant material for treatment of urinary incontinence |
CN101711254A (zh) * | 2007-06-19 | 2010-05-19 | 凯瑟拉生物制药有限公司 | 合成胆汁酸组合物、方法和制剂 |
JOP20180077A1 (ar) | 2007-06-19 | 2019-01-30 | Kythera Biopharmaceuticals Inc | تركيبات وطرق لحمض صفراوي تخليقي |
US20080318870A1 (en) | 2007-06-19 | 2008-12-25 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
US8242294B2 (en) | 2007-06-19 | 2012-08-14 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
US7943187B2 (en) | 2008-05-23 | 2011-05-17 | Bakr Rabie | Paeoniflorin preparations and uses thereof for fat reduction |
FR2937554B1 (fr) * | 2008-10-27 | 2010-11-12 | Yves Crassas | Solutions salines aqueuses pour la destruction de tissus graisseux |
MX337850B (es) * | 2009-03-02 | 2016-03-23 | Doris Hexsel | Lipoatrofia cosmetica medicinal. |
US10213441B2 (en) | 2009-03-02 | 2019-02-26 | Doris Hexsel | Medicinal cosmetic lipoatrophy |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
US20110086829A1 (en) * | 2009-10-09 | 2011-04-14 | Zadini Filiberto P | Compositions and methods for treating obesity |
GB2480632A (en) | 2010-05-25 | 2011-11-30 | Kythera Biopharmaceuticals Inc | Preparation of 12-keto and 12-alpha-hydroxy steroids |
US9127036B2 (en) | 2010-08-12 | 2015-09-08 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
US20120237492A1 (en) | 2011-02-18 | 2012-09-20 | Kythera Biopharmaceuticals, Inc. | Treatment of submental fat |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
EP2721047B1 (en) | 2011-06-16 | 2016-11-16 | Kythera Biopharmaceuticals, Inc. | Methods for the synthesis and purification of deoxycholic acid |
EA034320B1 (ru) * | 2011-08-23 | 2020-01-28 | Китера Биофармасьютикалз, Инк. | Композиции дезоксихолата натрия |
ES2478447T3 (es) | 2011-08-23 | 2014-07-22 | Kythera Biopharmaceuticals, Inc. | Formulaciones del ácido desoxicólico y sus sales |
MX350390B (es) * | 2011-08-23 | 2017-09-06 | Kythera Biopharmaceuticals Inc | Formulaciones de acido desoxicolico y sales del mismo. |
FI3581199T3 (fi) * | 2011-10-21 | 2023-08-18 | Endo Global Ventures | Menetelmiä turvottavan fibroskleroottisen pannikulopatian hoitamiseksi tai vähentämiseksi |
US8426471B1 (en) | 2011-12-19 | 2013-04-23 | Topokine Therapeutics, Inc. | Methods and compositions for reducing body fat and adipocytes |
EP2793813A1 (en) * | 2011-12-21 | 2014-10-29 | Motolese, Pasquale | Cosmetic composition and uses thereof in the treatment of lipodystrophies |
ES2968836T3 (es) | 2012-01-12 | 2024-05-14 | Endo Global Ventures | Enzima del clostridium histolyticum |
CA2869676C (en) | 2012-11-21 | 2015-06-23 | Topokine Therapeutics, Inc. | Uses and compositions comprising a thiazolidinedione and oleic acid for locally increasing subcutaneous fat |
NO2753788T3 (el) | 2013-05-10 | 2018-06-16 | ||
WO2014186504A1 (en) | 2013-05-15 | 2014-11-20 | Topokine Therapeutics, Inc. | Methods and compositions for topical delivery of prostaglandins to subcutaneous fat |
WO2015179282A1 (en) | 2014-05-20 | 2015-11-26 | Topokine Therapeutics, Inc. | Topical compositions comprising a thiazolidinedione |
WO2015186126A1 (en) * | 2014-06-01 | 2015-12-10 | Galmed Research And Development Ltd. | Fatty acid bile acid conjugates for treatment of lipodystrophy |
WO2015200425A1 (en) | 2014-06-27 | 2015-12-30 | Topokine Therapeutics, Inc. | Topical dosage regimen |
WO2015198150A2 (en) | 2014-06-27 | 2015-12-30 | Medy-Tox Inc. | Methods and compositions of bile acids and salts for reduction of fat |
US9687455B2 (en) | 2014-08-14 | 2017-06-27 | John Daniel Dobak | Sodium tetradecyl sulfate formulations for treatment of adipose tissue |
EP3915542B1 (en) | 2014-12-23 | 2023-11-22 | Dyve Biosciences, Inc. | Formulations for transdermal administration |
US9351945B1 (en) | 2015-02-27 | 2016-05-31 | John Daniel Dobak, III | Reduction of adipose tissue |
US9925170B2 (en) | 2015-10-01 | 2018-03-27 | Kythera Biopharmaceuticals, Inc. | Methods of adipolysis and compositions useful therein |
CA3003746A1 (en) * | 2015-11-04 | 2017-05-11 | Kythera Biopharmaceuticals, Inc. | Treatments of accumulated fat with deoxycholic acid and salts thereof |
JP6219430B2 (ja) * | 2016-03-18 | 2017-10-25 | キテラ バイオファーマシューティカルズ,インコーポレイテッド | デオキシコール酸およびその塩類の製剤 |
KR102527103B1 (ko) | 2016-06-06 | 2023-04-28 | 크리스탈 파마 에스.에이.유. | 디옥시콜린산 제조방법 및 디옥시콜린산의 제조에 유용한 중간물 |
US20180078621A1 (en) * | 2016-09-22 | 2018-03-22 | Kyoung Lack Lee | Composition for hypotonic lipolysis and manufacturing method thereof |
KR101841193B1 (ko) * | 2016-09-22 | 2018-03-22 | 이경락 | 저장성 지방 분해 조성물 및 그의 제조 방법 |
IL301796A (en) | 2017-03-01 | 2023-05-01 | Endo Ventures Ltd | A method for evaluating and treating cellulite |
WO2018183582A2 (en) | 2017-03-28 | 2018-10-04 | Endo Ventures Limited | Improved method of producing collagenase |
WO2018194427A1 (ko) * | 2017-04-21 | 2018-10-25 | 이기택 | 통증과 부종 그리고 부작용이 없는 국소지방 감소용 주사제 조성물 및 이의 제조방법 |
KR102093872B1 (ko) * | 2017-07-03 | 2020-03-27 | 진호성 | 지방제거용 주사제 조성물 및 이의 제조방법 |
US11161872B2 (en) * | 2017-08-03 | 2021-11-02 | Medytox Inc. | Methods for preparing bile acids |
JP6356329B2 (ja) * | 2017-09-27 | 2018-07-11 | キテラ バイオファーマシューティカルズ,インコーポレイテッド | デオキシコール酸およびその塩類の製剤 |
CN111511755A (zh) | 2017-10-24 | 2020-08-07 | 比奥尼斯有限责任公司 | 脱氧胆酸的制备 |
CN110302082A (zh) * | 2018-03-27 | 2019-10-08 | 上海同柏生物科技有限公司 | 用于减少身体脂肪沉积的技术及组合物制剂与应用 |
JP6594486B2 (ja) * | 2018-06-13 | 2019-10-23 | キテラ バイオファーマシューティカルズ,インコーポレイテッド | デオキシコール酸およびその塩類の製剤 |
KR102116238B1 (ko) * | 2018-08-28 | 2020-05-28 | 이경락 | 저장성 지방 분해 조성물 및 그의 제조 방법 |
EP3713551B1 (en) | 2018-10-16 | 2023-06-07 | Polithera, Inc. | Alcohol-based compositions and uses thereof |
US11439659B2 (en) * | 2018-12-03 | 2022-09-13 | The Regents Of The University Of California | Methods and compositions to prevent and treat inflammation and allergic reactions |
KR102172439B1 (ko) * | 2018-12-05 | 2020-10-30 | 송미희 | 지방 분해용 조성물 및 이를 포함하는 주사제 조성물 |
KR102064864B1 (ko) | 2019-02-08 | 2020-01-10 | (주)제테마 | 국소 주사용 조성물 |
KR102111346B1 (ko) | 2019-08-20 | 2020-05-22 | 아영창 | 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물 |
WO2023287261A1 (ko) | 2021-07-16 | 2023-01-19 | 주식회사 스카이테라퓨틱스 | 담즙산 또는 담즙산 염의 분자 회합체를 포함하는 화장료 조성물 |
EP4346837A1 (en) * | 2022-07-05 | 2024-04-10 | Glonova Pharma Co., Ltd. | Injectable composition comprising cytolytic compound in gel, gel-forming solution or gel-forming suspension for reduction of fat |
Family Cites Families (105)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4113882A (en) | 1974-10-21 | 1978-09-12 | Yamanouchi Pharmaceutical Co., Ltd. | Stabilized oral prostaglandin formulation and the process for the preparation thereof |
IT1202370B (it) | 1976-07-12 | 1989-02-09 | Hoffmann La Roche | Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti |
US4117121A (en) | 1977-04-22 | 1978-09-26 | Hoffmann-La Roche Inc. | Method of increasing bile flow and decreasing lipid levels |
IT8167097A0 (it) | 1981-01-26 | 1981-01-26 | Unilever Nv | Composizione cosmetica per il trattamento della pelle o dei capelli |
US5288498A (en) | 1985-05-01 | 1994-02-22 | University Of Utah Research Foundation | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments |
GB8417895D0 (en) | 1984-07-13 | 1984-08-15 | Marples B A | Pharmaceutical anti-fungal composition |
JPS61158995A (ja) * | 1984-12-28 | 1986-07-18 | Takara Shironaga | 脂肪肝,胆石,胃粘膜障害発生の予防薬または治療薬 |
US4866044A (en) * | 1985-07-09 | 1989-09-12 | Takeda Chemical Industries, Ltd. | Solubilized composition of poorly-soluble pharmaceutical product |
IT1213453B (it) | 1985-08-02 | 1989-12-20 | Merz & Co Gmbh & Co | Composizione farmaceutica. |
US5326562A (en) | 1986-06-03 | 1994-07-05 | Incyte Pharmaceuticals, Inc. | Pharmaceutical dosage unit for treating inflammation comprising protease nexin-I |
US4952411A (en) | 1987-02-25 | 1990-08-28 | Trustees Of Columbia University In The City Of New York | Method of inhibiting the transmission of AIDS virus |
US5690954A (en) | 1987-05-22 | 1997-11-25 | Danbiosyst Uk Limited | Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material |
US4994439A (en) | 1989-01-19 | 1991-02-19 | California Biotechnology Inc. | Transmembrane formulations for drug administration |
IL89530A0 (en) | 1989-03-08 | 1989-09-10 | Jeffrey J Feigenbaum | Compositions containing forskolin |
GB8909022D0 (en) | 1989-04-20 | 1989-06-07 | Cortecs Ltd | Pharmaceutical compositions |
EP0408174A1 (en) | 1989-07-12 | 1991-01-16 | Warner-Lambert Company | Antiseptic composition containing hexahydro-5-pyrimidinamine compounds |
AU6461090A (en) | 1989-10-30 | 1991-05-02 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
US5085864A (en) | 1989-10-30 | 1992-02-04 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
CA2033725C (en) | 1990-01-24 | 2001-05-29 | Folker Pittrof | Pharmaceutical and cosmetic compositions containing a salt of cholanic acid |
US6120805A (en) | 1990-04-06 | 2000-09-19 | Rhone-Poulenc Rorer Sa | Microspheres, process for their preparation and their use |
JP3032315B2 (ja) * | 1991-01-14 | 2000-04-17 | 健二 片桐 | 脂肪肝治療剤 |
GB9212511D0 (en) | 1992-06-12 | 1992-07-22 | Cortecs Ltd | Pharmaceutical compositions |
US5674855A (en) | 1992-08-12 | 1997-10-07 | The Rogosin Institute | Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions |
US5344822A (en) | 1992-08-12 | 1994-09-06 | The Rogosin Institute | Methods useful in endotoxin prophylaxis and therapy |
US6663885B1 (en) | 1993-03-15 | 2003-12-16 | A. Natterman & Cie Gmbh | Aqueous liposome system and a method for the preparation of such a liposome system |
GB9320597D0 (en) | 1993-10-06 | 1993-11-24 | Proteus Molecular Design | Improvements in and realting to vaccines |
US5395545A (en) | 1993-10-21 | 1995-03-07 | Akzo N.V. | Cleaning solution for automated analyzers |
ATE236617T1 (de) | 1994-12-22 | 2003-04-15 | Astrazeneca Ab | Aerosol-arzneiformulierungen |
JP2740153B2 (ja) | 1995-03-07 | 1998-04-15 | エフ・ホフマン−ラ ロシユ アーゲー | 混合ミセル |
US5616342A (en) | 1995-04-11 | 1997-04-01 | Pdt, Inc. | Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof |
US5759445A (en) | 1995-05-24 | 1998-06-02 | Matsushita Electric Industrial Co., Ltd. | Lipid-dispersed solution and process for producing the same |
US20040101569A1 (en) | 1996-05-16 | 2004-05-27 | Lorus Therapeutics Inc. | Immunomodulating compositions from bile |
US6255502B1 (en) | 1996-07-11 | 2001-07-03 | Farmarc Nederland B.V. | Pharmaceutical composition containing acid addition salt of basic drug |
US5952392A (en) | 1996-09-17 | 1999-09-14 | Avanir Pharmaceuticals | Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition |
US7351421B2 (en) | 1996-11-05 | 2008-04-01 | Hsing-Wen Sung | Drug-eluting stent having collagen drug carrier chemically treated with genipin |
CA2282411A1 (en) | 1997-02-27 | 1998-09-03 | Nippon Shinyaku Co., Ltd. | Fat emulsion for oral administration |
US5891083A (en) | 1997-04-22 | 1999-04-06 | Capella; Rafael F. | Suction lipolysis |
US20020107291A1 (en) | 1997-05-26 | 2002-08-08 | Vincenzo De Tommaso | Clear, injectable formulation of an anesthetic compound |
US6197327B1 (en) | 1997-06-11 | 2001-03-06 | Umd, Inc. | Device and method for treatment of dysmenorrhea |
US6416779B1 (en) | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
AU8067198A (en) | 1997-06-13 | 1998-12-30 | University Of Nebraska Board Of Regents | Compositions for delivery of biological agents and methods for the preparation thereof |
US6638621B2 (en) | 2000-08-16 | 2003-10-28 | Lyotropic Therapeutics, Inc. | Coated particles, methods of making and using |
US6281175B1 (en) * | 1997-09-23 | 2001-08-28 | Scimed Life Systems, Inc. | Medical emulsion for lubrication and delivery of drugs |
US6054421A (en) * | 1997-09-23 | 2000-04-25 | Scimed Life Systems, Inc. | Medical emulsion lubricant |
US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
US6221378B1 (en) | 1998-02-10 | 2001-04-24 | Generex Pharmaceuticals Incorporated | Mixed micellar delivery system and method of preparation |
US6251428B1 (en) | 1998-07-24 | 2001-06-26 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
US20050158408A1 (en) | 1998-07-24 | 2005-07-21 | Yoo Seo H. | Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof |
US7303768B2 (en) | 1998-07-24 | 2007-12-04 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
TW570805B (en) * | 1998-09-01 | 2004-01-11 | Hoffmann La Roche | Water-soluble pharmaceutical composition in an ionic complex |
SE9803240D0 (sv) | 1998-09-24 | 1998-09-24 | Diabact Ab | A pharmaceutical composition having a rapid action |
US6417179B1 (en) | 1998-10-13 | 2002-07-09 | Craig G. Burkhart | Ear wax solution |
US6451286B1 (en) | 1998-12-21 | 2002-09-17 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds |
US6849263B2 (en) | 1998-12-21 | 2005-02-01 | Generex Pharmaceutical Incorporated | Pharmaceutical compositions for buccal delivery of pain relief medications |
US6375975B1 (en) | 1998-12-21 | 2002-04-23 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary application |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
RU2250763C2 (ru) | 1999-03-03 | 2005-04-27 | Эли Лилли Энд Компани | Фармацевтические препараты эхинокандина, содержащие мицелообразующие поверхностно-активные вещества |
US6350432B1 (en) | 1999-03-19 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Pressurized container having an aerosolized pharmaceutical composition |
US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
US6489312B1 (en) * | 1999-06-15 | 2002-12-03 | Medimmune Oncology, Inc. | Pharmaceutical formulations comprising aminoalkyl phosphorothioates |
US6225343B1 (en) | 1999-06-16 | 2001-05-01 | Nastech Pharmaceutical Company, Inc. | Compositions and methods comprising morphine gluconate |
KR100848344B1 (ko) | 2000-02-04 | 2008-07-25 | 유서홍 | 담즙산 함유 청정 수용액 제형의 제조 |
GB0009773D0 (en) | 2000-04-19 | 2000-06-07 | Univ Cardiff | Particulate composition |
FR2813189B1 (fr) | 2000-08-31 | 2003-02-28 | Oreal | Creme cosmetique moussante pour le traitement des peaux grasses |
CA2422178A1 (en) * | 2000-09-08 | 2002-03-14 | Dow Global Technologies Inc. | Sequential detection ion chromatography |
WO2002041837A2 (en) | 2000-11-22 | 2002-05-30 | Rxkinetix, Inc. | Treatment of mucositis |
JP2004515532A (ja) | 2000-12-13 | 2004-05-27 | フェヘール ヤーノシュ | 消化障害及び関連する疾患を治療するための医薬組成物 |
US20040022862A1 (en) | 2000-12-22 | 2004-02-05 | Kipp James E. | Method for preparing small particles |
US20030072807A1 (en) | 2000-12-22 | 2003-04-17 | Wong Joseph Chung-Tak | Solid particulate antifungal compositions for pharmaceutical use |
US7037528B2 (en) | 2000-12-22 | 2006-05-02 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
US20030053956A1 (en) | 2001-01-24 | 2003-03-20 | Thomas Hofmann | Alkylaryl polyether alcohol polymers for treatment and prophylaxis of snoring, sleep apnea, sudden infant death syndrome and for improvement of nasal breathing |
SE0100901D0 (sv) | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | New composition |
CA2442539C (en) | 2001-03-27 | 2011-11-08 | Phares Pharmaceutical Research N.V. | Method and composition for solubilising a biologically active compound with low water solubility |
CA2446060A1 (en) | 2001-05-07 | 2002-11-14 | Corium International | Compositions and delivery systems for administration of a local anesthetic agent |
CN100350977C (zh) | 2001-06-14 | 2007-11-28 | 大塚制药株式会社 | 药物组合物 |
US20030083286A1 (en) | 2001-08-22 | 2003-05-01 | Ching-Leou Teng | Bioadhesive compositions and methods for enhanced intestinal drug absorption |
US7112340B2 (en) | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
US6713470B2 (en) | 2002-01-22 | 2004-03-30 | Ml Laboratories Plc | Method of treatment |
GB0207529D0 (en) * | 2002-04-02 | 2002-05-08 | Norbrook Lab Ltd | Injectable veterinary composition for small animals |
US20040018242A1 (en) | 2002-05-06 | 2004-01-29 | Elan Pharma International Ltd. | Nanoparticulate nystatin formulations |
AU2003233653B2 (en) | 2002-05-23 | 2008-08-07 | Umd, Inc. | Compositions and method for transmucosal drug delivery and cryoprotection |
US20040220283A1 (en) | 2002-07-29 | 2004-11-04 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
EP1539122B1 (en) | 2002-07-29 | 2014-01-29 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
US20050019404A1 (en) | 2003-06-30 | 2005-01-27 | Hsing-Wen Sung | Drug-eluting biodegradable stent |
US20050163821A1 (en) | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
KR100482269B1 (ko) | 2002-10-08 | 2005-04-14 | 센츄론(주) | 2,6-디이소프로필페놀을 활성성분으로 하는 수용액상의마취용 주사제 및 그 제조방법 |
CN1708270A (zh) | 2002-10-29 | 2005-12-14 | 转化医药公司 | 丙泊酚与半胱氨酸 |
US20050079228A1 (en) | 2003-05-30 | 2005-04-14 | Ashish Jaiswal | Clear, stable topical compositions of clarithromycin and processes for their preparation |
JP2007503439A (ja) | 2003-08-22 | 2007-02-22 | アクティブバイオティクス インコーポレイティッド | リファマイシンアナログおよびそれらの使用法 |
DE10349979B4 (de) * | 2003-10-24 | 2006-05-18 | Sanofi-Aventis Deutschland Gmbh | Medikamentöse gezielte lokale Lipolyse |
US20050089555A1 (en) | 2003-10-24 | 2005-04-28 | Aventis Pharma Deutschland Gmbh | Medicinal targeted local lipolysis |
DE10361067A1 (de) | 2003-12-22 | 2005-07-14 | Aventis Pharma Deutschland Gmbh | Medikamentöse Lipolyse von Fettansammlungen |
AU2004308971A1 (en) * | 2003-12-22 | 2005-07-14 | Aventis Pharmaceuticals Inc. | Injectable phosphatidylcholine preparations |
US20050143347A1 (en) | 2003-12-22 | 2005-06-30 | Aventis Pharma Deutschland Gmbh | Medicinal lipolysis of accumulations of fat |
KR100638041B1 (ko) | 2003-12-24 | 2006-10-23 | 주식회사 삼양사 | 수용성 약물의 경구투여용 나노입자 조성물 및 그의제조방법 |
US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
DK1758590T3 (da) | 2004-05-19 | 2011-11-21 | Los Angeles Biomed Res Inst | Anvendelse af et detergent til ikke-kirurgisk fjernelse af fedt |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
FR2870741B1 (fr) | 2004-05-25 | 2008-03-14 | Coletica Sa | Phase lamellaires hydratees ou liposomes, contenant une monoamine grasse ou un polymere cationique favorisant la penetration intercellulaire, et composition cosmetique ou pharmaceutique la contenant. |
ES2313352T3 (es) | 2004-06-03 | 2009-03-01 | Bracco Research S.A. | Ensamblaje de liposomas para uso terapeutico y/o diagnostico. |
US20050287199A1 (en) | 2004-06-28 | 2005-12-29 | Teresa Ann Denney | Therapeutic micro nutrient composition for lipolysis and drug delivery |
BRPI0418963A (pt) * | 2004-07-20 | 2007-12-04 | Libbs Farmaceutica Ltda | composição para redução de gordura localizada, uso de compostos tensoativos farmceuticamente aceitáveis e métodos para redução de gordura localizada |
US20060074057A1 (en) | 2004-10-04 | 2006-04-06 | Eric Marchewitz | Use of chenodeoxycholic acid for reducing adipose tissue |
US20060222695A1 (en) | 2005-04-01 | 2006-10-05 | Filiberto Zadini | Deoxycholic acid liposome-based dermatological topical preparation |
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