GT200100064A - Inhibidor del intercambiador de sodio - hidrogeno de tipo 1. - Google Patents

Inhibidor del intercambiador de sodio - hidrogeno de tipo 1.

Info

Publication number
GT200100064A
GT200100064A GT200100064A GT200100064A GT200100064A GT 200100064 A GT200100064 A GT 200100064A GT 200100064 A GT200100064 A GT 200100064A GT 200100064 A GT200100064 A GT 200100064A GT 200100064 A GT200100064 A GT 200100064A
Authority
GT
Guatemala
Prior art keywords
hydrogen
type
inhibitor
nhe1 inhibitor
exchanger inhibitor
Prior art date
Application number
GT200100064A
Other languages
English (en)
Inventor
Weichao George Chen
Eric David Cox
Angel Guzman-Perez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200100064A publication Critical patent/GT200100064A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE UN INHIBIDOR DE NHE1, METODOS PARA UTILIZAR EL INHIBIDOR DE NHE1 Y COMPOSICIONES FARMACEUTICAS QUE CONTIENE EL INHIBIDOR DE NHE1, EL INHIBIDOR DE NHE1 ES UTIL PARA LA REDUCCION DE LAS LESIONES TISULARES RESULTANTES DE LA ISQUEMIA DE LOS TEJIDOS. LAS COMPOSICIONES FARAMCEUTICAS DE LA PRESENTE INVECION TIENEN APLICACION EN TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES, ARTEROESCLEROSIS, HIPERTENSION, ARRITMIA, ANGINA DE PECHO, HIPERTROFIA CADIACA, ENFERMEDADES RENALES, REESTENOSIS, CANCER, ETC.
GT200100064A 2000-04-28 2001-04-20 Inhibidor del intercambiador de sodio - hidrogeno de tipo 1. GT200100064A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28

Publications (1)

Publication Number Publication Date
GT200100064A true GT200100064A (es) 2002-03-22

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200100064A GT200100064A (es) 2000-04-28 2001-04-20 Inhibidor del intercambiador de sodio - hidrogeno de tipo 1.

Country Status (40)

Country Link
EP (1) EP1276737A1 (es)
JP (1) JP2003531900A (es)
KR (1) KR20020093079A (es)
CN (1) CN1225466C (es)
AP (1) AP2002002651A0 (es)
AR (1) AR028375A1 (es)
AU (1) AU2001235896A1 (es)
BG (1) BG107139A (es)
BR (1) BR0110268A (es)
CA (1) CA2407535A1 (es)
CO (1) CO5221125A1 (es)
CR (1) CR6797A (es)
CZ (1) CZ20023408A3 (es)
DZ (1) DZ3310A1 (es)
EA (1) EA004882B1 (es)
EE (1) EE200200615A (es)
GT (1) GT200100064A (es)
HN (1) HN2001000042A (es)
HR (1) HRP20020851A2 (es)
HU (1) HUP0300651A2 (es)
IL (1) IL152075A0 (es)
IS (2) IS6567A (es)
MA (1) MA26897A1 (es)
MX (1) MXPA02010600A (es)
MY (1) MY133842A (es)
NO (1) NO20025132L (es)
NZ (1) NZ521348A (es)
OA (1) OA12256A (es)
PA (1) PA8513301A1 (es)
PE (1) PE20011270A1 (es)
PL (1) PL357765A1 (es)
SK (1) SK14872002A3 (es)
SV (1) SV2002000418A (es)
TN (1) TNSN01065A1 (es)
TR (1) TR200202439T2 (es)
UA (1) UA73348C2 (es)
UY (1) UY26680A1 (es)
WO (1) WO2001083470A1 (es)
YU (1) YU79602A (es)
ZA (1) ZA200208605B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004518686A (ja) * 2001-01-31 2004-06-24 ファイザー・プロダクツ・インク ナトリウム−水素交換輸送体１型阻害剤のエタノラート
EP1456181A1 (en) * 2001-12-19 2004-09-15 Pfizer Products Inc. Methods for preparing sodium-hydrogen exchanger type-1 inhibitors
MXPA04008646A (es) * 2002-05-02 2004-12-06 Pfizer Prod Inc Tratamiento para la diabetes y complicaciones diabeticas con inhibidores del nhe-1.
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
ES2220185B1 (es) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas Nuevo peptido inhibidor del intercambiador na+/h+ (pinhe), y sus aplicaciones.
MXPA05008612A (es) * 2003-02-14 2005-12-05 Smithkline Beecham Corp Compuestos novedosos.
RU2518741C1 (ru) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" СРЕДСТВО, ИНГИБИРУЮЩЕЕ Na+/H+-ОБМЕН, И ГАЛОГЕНИДЫ 1-ДИАЛКИЛАМИНОЭТИЛ-3-[ЗАМЕЩЕННЫЙ(ДИЗАМЕЩЕННЫЙ) ФЕНАЦИЛ]-2-АМИНОБЕНЗИМИДАЗОЛИЯ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU739403B2 (en) * 1998-02-27 2001-10-11 Pfizer Products Inc. N-((substituted five-membered di- or triaza diunsaturated ring)carbonyl) guanidine derivatives for the treatment of ischemia

Also Published As

Publication number Publication date
EE200200615A (et) 2004-04-15
WO2001083470A1 (en) 2001-11-08
UA73348C2 (en) 2005-07-15
HN2001000042A (es) 2001-07-09
HUP0300651A2 (hu) 2003-07-28
HRP20020851A2 (en) 2005-02-28
JP2003531900A (ja) 2003-10-28
IL152075A0 (en) 2003-05-29
UY26680A1 (es) 2001-12-28
TR200202439T2 (tr) 2003-02-21
SV2002000418A (es) 2002-07-03
SK14872002A3 (sk) 2004-03-02
AR028375A1 (es) 2003-05-07
CN1225466C (zh) 2005-11-02
OA12256A (en) 2003-11-06
CA2407535A1 (en) 2001-11-08
MA26897A1 (fr) 2004-12-20
PA8513301A1 (es) 2003-09-05
EA200201023A1 (ru) 2003-02-27
CO5221125A1 (es) 2002-11-28
PE20011270A1 (es) 2001-12-12
CR6797A (es) 2004-05-17
BG107139A (bg) 2003-07-31
NO20025132D0 (no) 2002-10-25
AU2001235896A1 (en) 2001-11-12
IS6567A (is) 2002-09-24
EP1276737A1 (en) 2003-01-22
EA004882B1 (ru) 2004-08-26
PL357765A1 (en) 2004-07-26
KR20020093079A (ko) 2002-12-12
ZA200208605B (en) 2003-10-24
MXPA02010600A (es) 2003-03-10
YU79602A (en) 2006-05-25
DZ3310A1 (fr) 2001-11-07
IS6588A (is) 2002-10-21
AP2002002651A0 (en) 2002-12-31
CZ20023408A3 (cs) 2004-01-14
NO20025132L (no) 2002-12-12
NZ521348A (en) 2004-09-24
BR0110268A (pt) 2003-12-30
TNSN01065A1 (fr) 2005-11-10
MY133842A (en) 2007-11-30
CN1426404A (zh) 2003-06-25

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