NO20065368L - Terapeutiske blandinger inneholdende minst et pyrrolobenzodiazepinderivat og fludarabin - Google Patents

Terapeutiske blandinger inneholdende minst et pyrrolobenzodiazepinderivat og fludarabin

Info

Publication number
NO20065368L
NO20065368L NO20065368A NO20065368A NO20065368L NO 20065368 L NO20065368 L NO 20065368L NO 20065368 A NO20065368 A NO 20065368A NO 20065368 A NO20065368 A NO 20065368A NO 20065368 L NO20065368 L NO 20065368L
Authority
NO
Norway
Prior art keywords
fludarabine
compositions containing
therapeutic compositions
pyrrolobenzodiazepine derivative
pyrrolobenzodiazepine
Prior art date
Application number
NO20065368A
Other languages
English (en)
Other versions
NO338380B1 (no
Inventor
Patrick Delavault
Chris Pepper
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NO20065368L publication Critical patent/NO20065368L/no
Publication of NO338380B1 publication Critical patent/NO338380B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oppfinnelsen angår anvendelse av et terapeutisk preparat omfattende minst ett pyrrolobenzodiazepin-derivat kombinert med fludarabin for behandling av kreft og mer spesielt hematologiske sykdommer
NO20065368A 2004-04-27 2006-11-21 Anvendelse av et terapeutisk preparat av et PBD-derivat, samt et produkt derav NO338380B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0404424A FR2869231B1 (fr) 2004-04-27 2004-04-27 Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
PCT/FR2005/001025 WO2005105113A2 (fr) 2004-04-27 2005-04-26 Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine

Publications (2)

Publication Number Publication Date
NO20065368L true NO20065368L (no) 2006-11-21
NO338380B1 NO338380B1 (no) 2016-08-15

Family

ID=34947843

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065368A NO338380B1 (no) 2004-04-27 2006-11-21 Anvendelse av et terapeutisk preparat av et PBD-derivat, samt et produkt derav

Country Status (14)

Country Link
US (1) US8034808B2 (no)
EP (1) EP1742644B1 (no)
JP (1) JP5046922B2 (no)
AT (1) ATE538801T1 (no)
CA (1) CA2564603C (no)
CY (1) CY1112387T1 (no)
DK (1) DK1742644T3 (no)
ES (1) ES2377066T3 (no)
FR (1) FR2869231B1 (no)
NO (1) NO338380B1 (no)
PL (1) PL1742644T3 (no)
PT (1) PT1742644E (no)
SI (1) SI1742644T1 (no)
WO (1) WO2005105113A2 (no)

Families Citing this family (65)

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US20130058947A1 (en) 2011-09-02 2013-03-07 Stem Centrx, Inc Novel Modulators and Methods of Use
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CN110183470A (zh) 2011-10-14 2019-08-30 麦迪穆有限责任公司 吡咯并苯并二氮杂卓
BR112014009055B1 (pt) 2011-10-14 2021-12-14 Seattle Genetics, Inc. Compostos pirrolobenzodiazepinas, conjugados alvos, ligante de fármaco e uso dos ditos conjugados para tratar uma doença proliferativa
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CN104520324A (zh) 2012-02-24 2015-04-15 施特姆森特Rx股份有限公司 Dll3调节剂及其使用方法
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CN105102068B (zh) 2012-10-12 2018-06-01 Adc疗法责任有限公司 吡咯并苯并二氮杂卓-抗体结合物
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CA2894959C (en) 2012-12-21 2022-01-11 Spirogen Sarl Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
CN110452242A (zh) 2012-12-21 2019-11-15 麦迪穆有限责任公司 吡咯并苯并二氮杂卓及其结合物
HUE043851T2 (hu) 2013-02-22 2019-09-30 Abbvie Stemcentrx Llc Anti-DLL3-antitest-PBD konjugátumok és alkalmazásuk
KR102066318B1 (ko) 2013-03-13 2020-01-14 메디뮨 리미티드 피롤로벤조디아제핀 및 그의 컨쥬게이트
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JP2016538318A (ja) 2013-08-28 2016-12-08 ステムセントリックス， インコーポレイテッド 新規ｓｅｚ６モジュレーターおよび使用方法
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ES2960619T3 (es) 2014-02-28 2024-03-05 Hangzhou Dac Biotech Co Ltd Enlazadores cargados y sus usos para la conjugación
TW201617368A (zh) 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗ｍｆｉ２抗體及使用方法
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PT3191135T (pt) 2014-09-12 2020-11-12 Genentech Inc Anticorpos anti-her2 e imunoconjugados
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Also Published As

Publication number Publication date
ATE538801T1 (de) 2012-01-15
JP2007534730A (ja) 2007-11-29
FR2869231A1 (fr) 2005-10-28
US20070232592A1 (en) 2007-10-04
DK1742644T3 (da) 2012-04-16
JP5046922B2 (ja) 2012-10-10
EP1742644A2 (fr) 2007-01-17
PL1742644T3 (pl) 2012-05-31
ES2377066T3 (es) 2012-03-22
CA2564603A1 (en) 2005-11-10
CY1112387T1 (el) 2015-12-09
EP1742644B1 (fr) 2011-12-28
PT1742644E (pt) 2012-03-02
WO2005105113A3 (fr) 2007-02-22
NO338380B1 (no) 2016-08-15
FR2869231B1 (fr) 2008-03-14
SI1742644T1 (sl) 2012-03-30
WO2005105113A2 (fr) 2005-11-10
CA2564603C (fr) 2014-07-29
US8034808B2 (en) 2011-10-11

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