ATE554764T1 - Wirkungsvolle vereinfachte derivate von immunosuppressiva - Google Patents
Wirkungsvolle vereinfachte derivate von immunosuppressivaInfo
- Publication number
- ATE554764T1 ATE554764T1 AT03714131T AT03714131T ATE554764T1 AT E554764 T1 ATE554764 T1 AT E554764T1 AT 03714131 T AT03714131 T AT 03714131T AT 03714131 T AT03714131 T AT 03714131T AT E554764 T1 ATE554764 T1 AT E554764T1
- Authority
- AT
- Austria
- Prior art keywords
- immunosuppressants
- effective simplified
- derivatives
- present
- simplified derivatives
- Prior art date
Links
- 229960003444 immunosuppressant agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36434702P | 2002-03-13 | 2002-03-13 | |
| PCT/US2003/007759 WO2003077862A2 (en) | 2002-03-13 | 2003-03-13 | Potent, simplified derivatives of immunosuppressive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554764T1 true ATE554764T1 (de) | 2012-05-15 |
Family
ID=28041903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03714131T ATE554764T1 (de) | 2002-03-13 | 2003-03-13 | Wirkungsvolle vereinfachte derivate von immunosuppressiva |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7230021B2 (de) |
| EP (1) | EP1482933B1 (de) |
| JP (1) | JP2005531514A (de) |
| AT (1) | ATE554764T1 (de) |
| AU (1) | AU2003218141A1 (de) |
| WO (1) | WO2003077862A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7737134B2 (en) * | 2002-03-13 | 2010-06-15 | The Texas A & M University System | Anticancer agents and use |
| UY33827A (es) * | 2010-12-22 | 2012-07-31 | Abbott Lab | Proteínas de unión a media-inmunoglobulina y sus usos |
| US10407444B2 (en) | 2015-03-31 | 2019-09-10 | The Texas A&M University System | Alpha-amino pateamine A derivatives and methods for treating chronic lymphocytic leukemia |
| WO2017173313A1 (en) | 2016-03-31 | 2017-10-05 | The Texas A&M University System | Beta-amimo pateamine a derivatives and methods for treating chronic lymphocytic leukemia |
| WO2018212006A1 (ja) * | 2017-05-19 | 2018-11-22 | 昭和電工株式会社 | 電気化学的にゲルマンを製造する方法 |
| CN110891567B (zh) | 2017-05-24 | 2024-01-09 | 效应治疗股份有限公司 | 用于改善的抗肿瘤免疫应答的组合物和方法 |
| JP2021008453A (ja) | 2019-07-02 | 2021-01-28 | エフェクター・セラピューティクス，インコーポレーテッド | 翻訳阻害剤およびその使用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4548481A (en) | 1983-11-07 | 1985-10-22 | Nippon Kogaku K.K. | Variable magnification observation optical device |
| US4729996A (en) | 1986-05-29 | 1988-03-08 | Harbor Branch Oceanographic Institution, Inc. | Antitumor compositions and their methods of use |
| US4737510A (en) | 1986-09-30 | 1988-04-12 | The Board Of Trustees Of The University Of Illinois | Bioactive metabolites from the caribbean sponge agelas coniferin |
| US4808590A (en) | 1987-07-17 | 1989-02-28 | Harbor Branch Oceanographic Institution, Inc. | Antiviral, antitumor and antifungal compositions and their methods of use |
| GB9026658D0 (en) * | 1990-12-07 | 1991-01-23 | Pharma Mar Sa | Novel antitumoral and antiviral compound |
| EP0647645A1 (de) | 1993-10-12 | 1995-04-12 | Pharma Mar, S.A. | Antitumor- und antivirale Verbindung |
| US6057333A (en) | 1997-07-25 | 2000-05-02 | Harbor Branch Oceanographic Institution, Inc. | Discorhabdin compounds and methods of use |
-
2003
- 2003-03-13 AT AT03714131T patent/ATE554764T1/de active
- 2003-03-13 US US10/388,257 patent/US7230021B2/en not_active Expired - Lifetime
- 2003-03-13 JP JP2003575916A patent/JP2005531514A/ja active Pending
- 2003-03-13 WO PCT/US2003/007759 patent/WO2003077862A2/en not_active Ceased
- 2003-03-13 EP EP03714131A patent/EP1482933B1/de not_active Expired - Lifetime
- 2003-03-13 AU AU2003218141A patent/AU2003218141A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005531514A (ja) | 2005-10-20 |
| EP1482933B1 (de) | 2012-04-25 |
| WO2003077862A2 (en) | 2003-09-25 |
| WO2003077862A3 (en) | 2004-03-25 |
| AU2003218141A1 (en) | 2003-09-29 |
| US20030216436A1 (en) | 2003-11-20 |
| EP1482933A2 (de) | 2004-12-08 |
| AU2003218141A8 (en) | 2003-09-29 |
| EP1482933A4 (de) | 2006-04-12 |
| US7230021B2 (en) | 2007-06-12 |
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