ATE453636T1 - Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren - Google Patents
Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahrenInfo
- Publication number
- ATE453636T1 ATE453636T1 AT04782152T AT04782152T ATE453636T1 AT E453636 T1 ATE453636 T1 AT E453636T1 AT 04782152 T AT04782152 T AT 04782152T AT 04782152 T AT04782152 T AT 04782152T AT E453636 T1 ATE453636 T1 AT E453636T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- diseases
- isoindol
- dihydro
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Manufacturing & Machinery (AREA)
- Communicable Diseases (AREA)
- Ceramic Engineering (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Structural Engineering (AREA)
- Materials Engineering (AREA)
- Endocrinology (AREA)
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- Inorganic Chemistry (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49787803P | 2003-08-25 | 2003-08-25 | |
US10/926,238 US7320992B2 (en) | 2003-08-25 | 2004-08-24 | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
PCT/US2004/027595 WO2005021532A1 (en) | 2003-08-25 | 2004-08-25 | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE453636T1 true ATE453636T1 (de) | 2010-01-15 |
Family
ID=34228620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04782152T ATE453636T1 (de) | 2003-08-25 | 2004-08-25 | Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren |
Country Status (10)
Country | Link |
---|---|
US (1) | US7320992B2 (de) |
EP (1) | EP1664027B1 (de) |
JP (1) | JP2007503450A (de) |
AT (1) | ATE453636T1 (de) |
AU (1) | AU2004269000A1 (de) |
CA (1) | CA2534570A1 (de) |
DE (1) | DE602004024900D1 (de) |
ES (1) | ES2337062T3 (de) |
MX (1) | MXPA06001923A (de) |
WO (1) | WO2005021532A1 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7745641B2 (en) * | 2005-04-19 | 2010-06-29 | Kyowa Hakko Kirin Co., Ltd. | Nitrogen-containing heterocyclic compound |
WO2006134989A1 (ja) * | 2005-06-15 | 2006-12-21 | Kyowa Hakko Kogyo Co., Ltd. | 含窒素複素環化合物 |
KR20080042158A (ko) * | 2005-08-31 | 2008-05-14 | 셀진 코포레이션 | 이소인돌-이미드 화합물과 이를 포함하는 조성물 및 이를이용한 방법 |
US7989461B2 (en) | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
US8110681B2 (en) * | 2006-03-17 | 2012-02-07 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Compounds for the treatment of spinal muscular atrophy and other uses |
AR060635A1 (es) | 2006-04-27 | 2008-07-02 | Banyu Pharma Co Ltd | Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer |
EP2046753A2 (de) * | 2006-07-06 | 2009-04-15 | Brystol-Myers Squibb Company | Pyridon/hydroxypyridin-11-beta-hydroxysteroid-dehydrogenase-hemmer vom typ i |
JP2010515744A (ja) * | 2007-01-10 | 2010-05-13 | アルバニー モレキュラー リサーチ, インコーポレイテッド | 5−ピリジノン置換インダゾール |
US20110053953A1 (en) * | 2007-02-09 | 2011-03-03 | Abdelmalik Slassi | AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613 |
US8153659B2 (en) * | 2007-03-20 | 2012-04-10 | Celgene Corporation | 4′-O-substituted isoindoline derivatives and compositions comprising and methods of using the same |
KR20100044225A (ko) * | 2007-07-21 | 2010-04-29 | 알바니 몰레큘라 리써치, 인크. | 5-피리디논 치환된 인다졸 |
TW200918062A (en) * | 2007-09-12 | 2009-05-01 | Wyeth Corp | Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists |
EP2573080A1 (de) * | 2007-09-27 | 2013-03-27 | The United States of America, as Represented by the Secretary, Department of Health and Human Services | Isoindolinverbindungen zur Behandlung von spinaler Muskelatrophie und für andere Anwendungen |
AU2008315048A1 (en) | 2007-10-23 | 2009-04-30 | Msd K.K. | Pyridone-substituted-dihydropyrazolopyrimidinone derivative |
KR101068835B1 (ko) * | 2007-10-26 | 2011-09-30 | 한국과학기술연구원 | 베타-아밀로이드 집적체 및 피브릴에 우수한 결합 친화도를가지는 이소인돌론 화합물 및 이의 제조 방법 |
JP5632612B2 (ja) * | 2007-12-05 | 2014-11-26 | あすか製薬株式会社 | ラクタム化合物又はその塩及びppar活性化剤 |
US20110092452A1 (en) * | 2008-03-05 | 2011-04-21 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating pancreatic cancer |
MX317270B (es) | 2008-05-08 | 2014-01-20 | Basf Se | Procedimiento para la obtencion de arilcarboxamidas. |
GB0811643D0 (en) | 2008-06-25 | 2008-07-30 | Cancer Rec Tech Ltd | New therapeutic agents |
US20120030841A1 (en) | 2009-04-01 | 2012-02-02 | Basf Se | Isoxazoline compounds for combating invertebrate pests |
ES2604305T3 (es) * | 2009-07-14 | 2017-03-06 | Nerviano Medical Sciences S.R.L. | 3-oxo-2,3-dihidro-1H-isoindol-4-carboxamida con inhibición selectiva de PARP-1 |
IN2012DN02139A (de) * | 2009-09-10 | 2015-08-07 | Novartis Ag | |
SI2485731T1 (sl) * | 2009-10-06 | 2016-09-30 | Millennium Pharmaceuticals, Inc. | Heterociklične spojine, ki se uporabljajo kot inhibitorji pdk1 |
US8440710B2 (en) | 2009-10-15 | 2013-05-14 | Hoffmann-La Roche Inc. | HSL inhibitors useful in the treatment of diabetes |
CA2786950C (en) | 2009-12-23 | 2019-01-15 | Takeda Pharmaceutical Company Limited | Fused heteroaromatic pyrrolidinones as syk inhibitors |
EP2723739B1 (de) | 2011-06-22 | 2016-08-24 | Takeda Pharmaceutical Company Limited | Substituierte 6-aza-isoindolin-1-on-derivate |
TW201321371A (zh) | 2011-10-14 | 2013-06-01 | Incyte Corp | 做為akt抑制劑之異吲哚啉酮及吡咯并吡啶酮衍生物 |
JP6211509B2 (ja) | 2012-03-02 | 2017-10-11 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
JP6211530B2 (ja) * | 2012-11-19 | 2017-10-11 | 武田薬品工業株式会社 | 含窒素複素環化合物 |
CN105579457B (zh) * | 2013-03-20 | 2017-08-04 | 拜耳制药股份公司 | 取代的n‑联苯‑3‑乙酰基氨基‑苯甲酰胺和n‑[3‑(乙酰基氨基)苯基]‑联苯‑甲酰胺及其作为wnt信号通路抑制剂用途 |
JP6526065B2 (ja) * | 2014-02-28 | 2019-06-05 | ニンバス ラクシュミ, インコーポレイテッド | Tyk2阻害剤およびその使用 |
AU2015233094B2 (en) | 2014-03-17 | 2017-04-27 | Pfizer Inc. | Diacylglycerol acyltransferase 2 inhibitors for use in the treatment of metabolic and related disorders |
US10208046B2 (en) | 2014-05-16 | 2019-02-19 | Takeda Pharmaceutical Company Limited | Nitrogen-containing heterocyclic compound |
SI3186241T1 (sl) * | 2014-08-29 | 2021-03-31 | Chdi Foundation, Inc. | Sonde za slikanje Huntingtonovega proteina |
GB201517217D0 (en) | 2015-09-29 | 2015-11-11 | Astex Therapeutics Ltd And Cancer Res Technology Ltd | Pharmaceutical compounds |
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WO2017151409A1 (en) | 2016-02-29 | 2017-09-08 | University Of Florida Research Foundation, Incorporated | Chemotherapeutic methods |
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2004
- 2004-08-24 US US10/926,238 patent/US7320992B2/en active Active
- 2004-08-25 MX MXPA06001923A patent/MXPA06001923A/es not_active Application Discontinuation
- 2004-08-25 AT AT04782152T patent/ATE453636T1/de not_active IP Right Cessation
- 2004-08-25 ES ES04782152T patent/ES2337062T3/es active Active
- 2004-08-25 EP EP04782152A patent/EP1664027B1/de active Active
- 2004-08-25 AU AU2004269000A patent/AU2004269000A1/en not_active Abandoned
- 2004-08-25 CA CA002534570A patent/CA2534570A1/en not_active Abandoned
- 2004-08-25 WO PCT/US2004/027595 patent/WO2005021532A1/en active Application Filing
- 2004-08-25 DE DE602004024900T patent/DE602004024900D1/de active Active
- 2004-08-25 JP JP2006524818A patent/JP2007503450A/ja not_active Withdrawn
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US20050054670A1 (en) | 2005-03-10 |
EP1664027B1 (de) | 2009-12-30 |
JP2007503450A (ja) | 2007-02-22 |
CA2534570A1 (en) | 2005-03-10 |
ES2337062T3 (es) | 2010-04-20 |
MXPA06001923A (es) | 2006-05-17 |
WO2005021532A1 (en) | 2005-03-10 |
DE602004024900D1 (de) | 2010-02-11 |
EP1664027A1 (de) | 2006-06-07 |
AU2004269000A1 (en) | 2005-03-10 |
US7320992B2 (en) | 2008-01-22 |
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