DE602004024900D1 - Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren - Google Patents
Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahrenInfo
- Publication number
- DE602004024900D1 DE602004024900D1 DE602004024900T DE602004024900T DE602004024900D1 DE 602004024900 D1 DE602004024900 D1 DE 602004024900D1 DE 602004024900 T DE602004024900 T DE 602004024900T DE 602004024900 T DE602004024900 T DE 602004024900T DE 602004024900 D1 DE602004024900 D1 DE 602004024900D1
- Authority
- DE
- Germany
- Prior art keywords
- diseases
- compounds
- isoindol
- dihydro
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Oncology (AREA)
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- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49787803P | 2003-08-25 | 2003-08-25 | |
US10/926,238 US7320992B2 (en) | 2003-08-25 | 2004-08-24 | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
PCT/US2004/027595 WO2005021532A1 (en) | 2003-08-25 | 2004-08-25 | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004024900D1 true DE602004024900D1 (de) | 2010-02-11 |
Family
ID=34228620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004024900T Active DE602004024900D1 (de) | 2003-08-25 | 2004-08-25 | Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren |
Country Status (10)
Country | Link |
---|---|
US (1) | US7320992B2 (de) |
EP (1) | EP1664027B1 (de) |
JP (1) | JP2007503450A (de) |
AT (1) | ATE453636T1 (de) |
AU (1) | AU2004269000A1 (de) |
CA (1) | CA2534570A1 (de) |
DE (1) | DE602004024900D1 (de) |
ES (1) | ES2337062T3 (de) |
MX (1) | MXPA06001923A (de) |
WO (1) | WO2005021532A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2610446A1 (en) * | 2005-04-19 | 2006-10-26 | Kyowa Hakko Kogyo Co., Ltd. | Nitrogen-containing heterocyclic compound |
WO2006134989A1 (ja) * | 2005-06-15 | 2006-12-21 | Kyowa Hakko Kogyo Co., Ltd. | 含窒素複素環化合物 |
MX2008002765A (es) * | 2005-08-31 | 2008-04-07 | Celgene Corp | Compuestos de isoindol-imida y composiciones que la comprenden y metodos para usar los mismos. |
US7989461B2 (en) | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
US8110681B2 (en) | 2006-03-17 | 2012-02-07 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Compounds for the treatment of spinal muscular atrophy and other uses |
PE20080695A1 (es) | 2006-04-27 | 2008-06-28 | Banyu Pharma Co Ltd | Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel |
WO2008005910A2 (en) * | 2006-07-06 | 2008-01-10 | Bristol-Myers Squibb Company | Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors |
KR20090101370A (ko) * | 2007-01-10 | 2009-09-25 | 알바니 몰레큘라 리써치, 인크. | 5-피리디논 치환된 인다졸 |
US20110053953A1 (en) * | 2007-02-09 | 2011-03-03 | Abdelmalik Slassi | AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613 |
WO2008115516A2 (en) * | 2007-03-20 | 2008-09-25 | Celgene Corporation | 4'-o-substituted isoindoline derivatives and compositions comprising and methods of using the same |
CN101861311A (zh) * | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
TW200918062A (en) * | 2007-09-12 | 2009-05-01 | Wyeth Corp | Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists |
EP2215074B1 (de) * | 2007-09-27 | 2014-02-19 | The United States of America, as Represented by the Secretary, Department of Health and Human Services | Isoindolinverbindungen zur behandlung von spinaler muskelatrophie und für andere anwendungen |
EP2213673B1 (de) * | 2007-10-23 | 2013-06-05 | Msd K.K. | Pyridonsubstituiertes dihydropyrazolopyrimidinonderivat |
KR101068835B1 (ko) * | 2007-10-26 | 2011-09-30 | 한국과학기술연구원 | 베타-아밀로이드 집적체 및 피브릴에 우수한 결합 친화도를가지는 이소인돌론 화합물 및 이의 제조 방법 |
WO2009072581A1 (ja) * | 2007-12-05 | 2009-06-11 | Aska Pharmaceutical Co., Ltd. | ラクタム化合物又はその塩及びppar活性化剤 |
US20110092452A1 (en) * | 2008-03-05 | 2011-04-21 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating pancreatic cancer |
EA018518B1 (ru) | 2008-05-08 | 2013-08-30 | Басф Се | Способ получения арилкарбоксамидов |
GB0811643D0 (en) | 2008-06-25 | 2008-07-30 | Cancer Rec Tech Ltd | New therapeutic agents |
WO2010112545A1 (en) | 2009-04-01 | 2010-10-07 | Basf Se | Isoxazoline compounds for combating invertebrate pests |
EP2454237B1 (de) * | 2009-07-14 | 2016-09-07 | Nerviano Medical Sciences S.r.l. | 3-oxo-2, 3-dihydro-1h-isoindol-4-carboxamide mit selektiver parp-1-hemmung |
IN2012DN02139A (de) * | 2009-09-10 | 2015-08-07 | Novartis Ag | |
IN2012DN03883A (de) | 2009-10-06 | 2015-09-25 | Millennium Pharm Inc | |
US8440710B2 (en) | 2009-10-15 | 2013-05-14 | Hoffmann-La Roche Inc. | HSL inhibitors useful in the treatment of diabetes |
EA021568B1 (ru) | 2009-12-23 | 2015-07-30 | Такеда Фармасьютикал Компани Лимитед | Конденсированные гетероароматические пирролидиноны как ингибиторы syk |
US9056873B2 (en) | 2011-06-22 | 2015-06-16 | Takeda Pharmaceutical Company Limited | Substituted 6-aza-isoindolin-1-one derivatives |
US8895571B2 (en) | 2011-10-14 | 2014-11-25 | Incyte Corporation | Isoindolinone and pyrrolopyridinone derivatives as Akt inhibitors |
EP2821401B1 (de) | 2012-03-02 | 2020-09-09 | Takeda Pharmaceutical Company Limited | Dihydrochinolinon-verbindungen als modulatoren des muscarinischen m1 rezeptors |
US9777005B2 (en) * | 2012-11-19 | 2017-10-03 | Takeda Pharmaceutical Company Limited | Bicyclic heterocyclic compound containing a substituted pyrrole ring |
CN105579457B (zh) * | 2013-03-20 | 2017-08-04 | 拜耳制药股份公司 | 取代的n‑联苯‑3‑乙酰基氨基‑苯甲酰胺和n‑[3‑(乙酰基氨基)苯基]‑联苯‑甲酰胺及其作为wnt信号通路抑制剂用途 |
EP3110820B1 (de) * | 2014-02-28 | 2022-04-06 | Nimbus Lakshmi, Inc. | Tyk2-inhibitoren und verwendungen davon |
WO2015140658A1 (en) | 2014-03-17 | 2015-09-24 | Pfizer Inc. | Diacylglycerol acyltransferase 2 inhibitors for use in the treatment of metabolic and related disorders |
WO2015174534A1 (ja) * | 2014-05-16 | 2015-11-19 | 武田薬品工業株式会社 | 含窒素複素環化合物 |
DK3186241T3 (da) * | 2014-08-29 | 2021-01-11 | Chdi Foundation Inc | Prober til billeddannelse af huntington-protein |
GB201517216D0 (en) | 2015-09-29 | 2015-11-11 | Cancer Res Technology Ltd And Astex Therapeutics Ltd | Pharmaceutical compounds |
GB201517217D0 (en) | 2015-09-29 | 2015-11-11 | Astex Therapeutics Ltd And Cancer Res Technology Ltd | Pharmaceutical compounds |
US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
KR101789430B1 (ko) | 2016-06-28 | 2017-10-25 | 동국대학교 산학협력단 | Smo 저해 활성을 갖는 신규 화합물 및 이를 유효성분으로 포함하는 암 예방 또는 치료용 조성물 |
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2004
- 2004-08-24 US US10/926,238 patent/US7320992B2/en active Active
- 2004-08-25 AT AT04782152T patent/ATE453636T1/de not_active IP Right Cessation
- 2004-08-25 JP JP2006524818A patent/JP2007503450A/ja not_active Withdrawn
- 2004-08-25 AU AU2004269000A patent/AU2004269000A1/en not_active Abandoned
- 2004-08-25 WO PCT/US2004/027595 patent/WO2005021532A1/en active Application Filing
- 2004-08-25 ES ES04782152T patent/ES2337062T3/es active Active
- 2004-08-25 DE DE602004024900T patent/DE602004024900D1/de active Active
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- 2004-08-25 MX MXPA06001923A patent/MXPA06001923A/es not_active Application Discontinuation
- 2004-08-25 EP EP04782152A patent/EP1664027B1/de active Active
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EP1664027B1 (de) | 2009-12-30 |
ES2337062T3 (es) | 2010-04-20 |
AU2004269000A1 (en) | 2005-03-10 |
MXPA06001923A (es) | 2006-05-17 |
US7320992B2 (en) | 2008-01-22 |
ATE453636T1 (de) | 2010-01-15 |
WO2005021532A1 (en) | 2005-03-10 |
JP2007503450A (ja) | 2007-02-22 |
US20050054670A1 (en) | 2005-03-10 |
CA2534570A1 (en) | 2005-03-10 |
EP1664027A1 (de) | 2006-06-07 |
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