ATE355287T1 - 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten - Google Patents
2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheitenInfo
- Publication number
- ATE355287T1 ATE355287T1 AT03741829T AT03741829T ATE355287T1 AT E355287 T1 ATE355287 T1 AT E355287T1 AT 03741829 T AT03741829 T AT 03741829T AT 03741829 T AT03741829 T AT 03741829T AT E355287 T1 ATE355287 T1 AT E355287T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- cell proliferation
- trihydroquinazoline
- oxo
- derivative
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000004663 cell proliferation Effects 0.000 title abstract 2
- CTOUNZIAEBIWAW-UHFFFAOYSA-N 3,4-dihydro-1h-quinazolin-2-one Chemical class C1=CC=C2NC(=O)NCC2=C1 CTOUNZIAEBIWAW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38426502P | 2002-05-29 | 2002-05-29 | |
| US10/446,440 US7119111B2 (en) | 2002-05-29 | 2003-05-27 | 2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE355287T1 true ATE355287T1 (de) | 2006-03-15 |
Family
ID=29715321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03741829T ATE355287T1 (de) | 2002-05-29 | 2003-05-29 | 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1507776B1 (de) |
| JP (1) | JP2005533039A (de) |
| AT (1) | ATE355287T1 (de) |
| AU (1) | AU2003273579A1 (de) |
| CA (1) | CA2486530A1 (de) |
| DE (1) | DE60312154T2 (de) |
| ES (1) | ES2282646T3 (de) |
| MX (1) | MXPA04011579A (de) |
| PL (1) | PL373842A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20081692A1 (es) * | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
| US8153792B2 (en) * | 2007-02-13 | 2012-04-10 | Ab Science | Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors |
| CN102573994B (zh) * | 2009-08-06 | 2015-06-24 | 默克专利有限公司 | 双环脲化合物 |
-
2003
- 2003-05-29 JP JP2004509676A patent/JP2005533039A/ja active Pending
- 2003-05-29 EP EP03741829A patent/EP1507776B1/de not_active Expired - Lifetime
- 2003-05-29 PL PL03373842A patent/PL373842A1/xx not_active Application Discontinuation
- 2003-05-29 MX MXPA04011579A patent/MXPA04011579A/es unknown
- 2003-05-29 CA CA002486530A patent/CA2486530A1/en not_active Abandoned
- 2003-05-29 AT AT03741829T patent/ATE355287T1/de not_active IP Right Cessation
- 2003-05-29 DE DE60312154T patent/DE60312154T2/de not_active Expired - Lifetime
- 2003-05-29 AU AU2003273579A patent/AU2003273579A1/en not_active Abandoned
- 2003-05-29 ES ES03741829T patent/ES2282646T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL373842A1 (en) | 2005-09-19 |
| CA2486530A1 (en) | 2003-12-11 |
| MXPA04011579A (es) | 2005-03-07 |
| DE60312154D1 (de) | 2007-04-12 |
| ES2282646T3 (es) | 2007-10-16 |
| EP1507776A1 (de) | 2005-02-23 |
| AU2003273579A1 (en) | 2003-12-19 |
| JP2005533039A (ja) | 2005-11-04 |
| DE60312154T2 (de) | 2007-06-21 |
| EP1507776B1 (de) | 2007-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE320426T1 (de) | Harnstoffderivate und ihre verwendung | |
| DE602004015810D1 (de) | Substituierte isochinolinderivate und anwendungsverfahren | |
| DE602004024900D1 (de) | Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren | |
| IS6865A (is) | Setnar alkýlamínafleiður og aðferðir við notkun þeirra | |
| WO2004007457A3 (en) | Substituted benzylamine derivatives and methods of use | |
| MX2007013216A (es) | Derivados de amida substituida como inhibidores de la proteina de cinasa. | |
| NO20060278L (no) | Piperazinderivater og fremgangsmater for anvendelse | |
| DE60225556D1 (de) | Dpp-iv-inhibierende purin-derivative zur behandlung von diabetes | |
| WO2004005279A3 (en) | Substituted anthranilic amide derivatives and methods of use | |
| WO2003066630A3 (en) | Quinolinone derivatives for treating cell proliferation related disorders | |
| ATE440087T1 (de) | 2,4-diaminopyrimidinderivate, die sich als inhibitoren von pkc-theta eignen | |
| EA200601239A1 (ru) | Замещённые хинолиновые соединения | |
| CY1111070T1 (el) | Παραγωγα 2-αμινο-κουιναζολινης χρησιμα ως αναστολεις της β-σεκρετασης (bace) | |
| MXPA05010883A (es) | Derivados de amina ciclica y su uso en el tratamiento de trastornos inflamatorios relacionados mediados por bradiquinina. | |
| ATE367380T1 (de) | Zur behandlung von zns-erkrankungen geeignete piperazinylchinolinderivate | |
| ATE355287T1 (de) | 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten | |
| UA86051C2 (en) | Substituted quinoline compounds | |
| EP1619184A3 (de) | Harnstoffverbindungen als Kinaseinhibitoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |