ATE355287T1 - 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten - Google Patents

2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten

Info

Publication number
ATE355287T1
ATE355287T1 AT03741829T AT03741829T ATE355287T1 AT E355287 T1 ATE355287 T1 AT E355287T1 AT 03741829 T AT03741829 T AT 03741829T AT 03741829 T AT03741829 T AT 03741829T AT E355287 T1 ATE355287 T1 AT E355287T1
Authority
AT
Austria
Prior art keywords
treatment
cell proliferation
trihydroquinazoline
oxo
derivative
Prior art date
Application number
AT03741829T
Other languages
English (en)
Inventor
Qi Huang
Matthew Kaller
Thomas Nguyen
Mark H Norman
Robert Rzasa
Hui-Ling Wang
Wenge Zhong
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/446,440 external-priority patent/US7119111B2/en
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE355287T1 publication Critical patent/ATE355287T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT03741829T 2002-05-29 2003-05-29 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten ATE355287T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38426502P 2002-05-29 2002-05-29
US10/446,440 US7119111B2 (en) 2002-05-29 2003-05-27 2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use

Publications (1)

Publication Number Publication Date
ATE355287T1 true ATE355287T1 (de) 2006-03-15

Family

ID=29715321

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03741829T ATE355287T1 (de) 2002-05-29 2003-05-29 2-oxo-1,3,4-trihydrochinazolin derivative zur behandlung von zellproliferationskrankheiten

Country Status (9)

Country Link
EP (1) EP1507776B1 (de)
JP (1) JP2005533039A (de)
AT (1) ATE355287T1 (de)
AU (1) AU2003273579A1 (de)
CA (1) CA2486530A1 (de)
DE (1) DE60312154T2 (de)
ES (1) ES2282646T3 (de)
MX (1) MXPA04011579A (de)
PL (1) PL373842A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20081692A1 (es) * 2007-01-24 2008-12-18 Mochida Pharm Co Ltd Nuevo derivado de heterocicliden acetamida
EP2366703B1 (de) * 2007-02-13 2014-07-30 AB Science Polymorphe Form von 2-Amino-(Nitroaryl)-Thiazol-Derivat
AU2010281368C1 (en) * 2009-08-06 2016-08-04 Merck Patent Gmbh Novel bicyclic urea compounds

Also Published As

Publication number Publication date
EP1507776A1 (de) 2005-02-23
AU2003273579A1 (en) 2003-12-19
PL373842A1 (en) 2005-09-19
ES2282646T3 (es) 2007-10-16
JP2005533039A (ja) 2005-11-04
DE60312154T2 (de) 2007-06-21
DE60312154D1 (de) 2007-04-12
MXPA04011579A (es) 2005-03-07
EP1507776B1 (de) 2007-02-28
CA2486530A1 (en) 2003-12-11

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Legal Events

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