IT1202370B - Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti - Google Patents

Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti

Info

Publication number
IT1202370B
IT1202370B IT25194/77A IT2519477A IT1202370B IT 1202370 B IT1202370 B IT 1202370B IT 25194/77 A IT25194/77 A IT 25194/77A IT 2519477 A IT2519477 A IT 2519477A IT 1202370 B IT1202370 B IT 1202370B
Authority
IT
Italy
Prior art keywords
emolithic
lipoids
avoided
life
addition
Prior art date
Application number
IT25194/77A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT511176A external-priority patent/AT352881B/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of IT1202370B publication Critical patent/IT1202370B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT25194/77A 1976-07-12 1977-06-29 Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti IT1202370B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT511176A AT352881B (de) 1976-07-12 1976-07-12 Verfahren zur herstellung von injektions- loesungen
CH699477A CH628811A5 (en) 1976-07-12 1977-06-07 Injection solutions

Publications (1)

Publication Number Publication Date
IT1202370B true IT1202370B (it) 1989-02-09

Family

ID=25601846

Family Applications (1)

Application Number Title Priority Date Filing Date
IT25194/77A IT1202370B (it) 1976-07-12 1977-06-29 Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti

Country Status (18)

Country Link
US (1) US4158707A (it)
JP (1) JPS6051448B2 (it)
AU (1) AU517249B2 (it)
CA (1) CA1082596A (it)
DE (1) DE2730570A1 (it)
DK (1) DK149483C (it)
FR (2) FR2358161A1 (it)
GB (1) GB1587076A (it)
HK (1) HK26584A (it)
IE (1) IE46037B1 (it)
IL (1) IL52458A (it)
IT (1) IT1202370B (it)
LU (2) LU77708A1 (it)
MY (1) MY8500263A (it)
NL (1) NL189072C (it)
NZ (1) NZ184564A (it)
PH (1) PH16333A (it)
SE (1) SE448516B (it)

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DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
US4264583A (en) * 1979-07-25 1981-04-28 The Procter & Gamble Company Gallstone dissolution compositions and method
JPS57163313A (en) * 1981-03-31 1982-10-07 Nippon Shinyaku Co Ltd Vitamin e pharmaceutical and its preparation
JPH0768117B2 (ja) * 1983-05-06 1995-07-26 ベスター・インコーポレイテツド 薬剤放出調整用小胞製剤
IL72420A (en) * 1983-07-22 1987-10-30 Hoffmann La Roche Aqueous vitamin e solutions and their manufacture
JPH0818989B2 (ja) * 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
CA1264162A (en) * 1984-03-15 1990-01-02 Manfred Breuninger Glycerol ether phosphatides
US5002936A (en) * 1985-04-12 1991-03-26 Seymour Lieberman Lipophilic complexes of pharmacologically active inorganic mineral acid esters of organic compounds
US4831018A (en) * 1985-05-17 1989-05-16 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
CS275793B6 (en) * 1985-08-02 1992-03-18 Merz & Co Gmbh & Co Production method of the antivirus and antitumour agent
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
SE8505047L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Fettemulsion
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions
DE3903753A1 (de) * 1989-02-06 1990-08-23 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
US5085864A (en) * 1989-10-30 1992-02-04 Abbott Laboratories Injectable formulation for lipophilic drugs
DE3938030A1 (de) * 1989-11-13 1991-05-16 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
CA2033725C (en) * 1990-01-24 2001-05-29 Folker Pittrof Pharmaceutical and cosmetic compositions containing a salt of cholanic acid
CA2033714A1 (en) * 1990-01-25 1991-07-26 Alberto Ferro Pharmaceutical preparations
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
DE4122661C2 (de) * 1990-08-06 1996-07-11 Nattermann A & Cie Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie
ZA916314B (en) * 1990-08-17 1992-05-27 Hoffmann La Roche Use of mixed micelles
IL100874A (en) * 1991-02-08 1996-01-19 Pro Neuron Inc Oxiforin nucleosides and their composition, for use as medicines, their preparation and pharmaceutical preparations containing them
DE4336434A1 (de) * 1993-10-26 1995-04-27 Hoechst Ag Pharmazeutische Zubereitung für die parenterale, enterale und dermale Verabreichung von praktisch unlöslichen Arzneistoffen und Verfahren zu ihrer Herstellung
EP0682943B1 (de) * 1994-05-20 2003-08-20 GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF Lormetazepamhaltige Öl-in-Wasser-Emulsion
GB9426104D0 (en) * 1994-12-23 1995-02-22 Merck Sharp & Dohme Use of surfactants and emulsions
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
US5759445A (en) * 1995-05-24 1998-06-02 Matsushita Electric Industrial Co., Ltd. Lipid-dispersed solution and process for producing the same
GB2326337A (en) 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US6350738B1 (en) 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
US6767904B2 (en) 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
CA2442539C (en) * 2001-03-27 2011-11-08 Phares Pharmaceutical Research N.V. Method and composition for solubilising a biologically active compound with low water solubility
EP1730516A1 (en) * 2004-03-30 2006-12-13 Pfizer Products Incorporated Method and device for evaluation of pharmaceutical compositions
SI1758590T1 (sl) * 2004-05-19 2012-03-30 Los Angeles Biomed Res Inst Uporaba detergenta za nekirurško odstranitev maščobe
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
WO2008065502A1 (en) * 2006-11-29 2008-06-05 Pfizer Products Inc. Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein
WO2008125940A2 (en) * 2007-04-17 2008-10-23 Pfizer Products Inc. Nanoparticles comprising non-crystalline drug
WO2008135855A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
US20100080852A1 (en) * 2007-05-03 2010-04-01 Ronald Arthur Beyerinck Phamaceutical composition comprising nanoparticles and casein
WO2008135828A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
WO2008149192A2 (en) * 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
EP2178518A2 (en) * 2007-07-13 2010-04-28 Bend Research, Inc Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
WO2009073216A1 (en) * 2007-12-06 2009-06-11 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an amine-functionalized methacrylate copolymer
US9724362B2 (en) * 2007-12-06 2017-08-08 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
CN102058528B (zh) * 2009-11-13 2012-12-12 中国科学院上海药物研究所 一种黄豆苷元胶束及其制备方法
GB2480632A (en) 2010-05-25 2011-11-30 Kythera Biopharmaceuticals Inc Preparation of 12-keto and 12-alpha-hydroxy steroids
CA2827643C (en) 2011-02-18 2019-05-07 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
RU2682249C2 (ru) * 2012-05-31 2019-03-18 Терумо Кабусики Кайся рН-ЧУВСТВИТЕЛЬНЫЙ НОСИТЕЛЬ И СПОСОБ ЕГО ПОЛУЧЕНИЯ, И рН-ЧУВСТВИТЕЛЬНОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, И рН-ЧУВСТВИТЕЛЬНАЯ ЛЕКАРСТВЕННАЯ КОМПОЗИЦИЯ, ГДЕ КАЖДОЕ ИЗ НИХ СОДЕРЖИТ НОСИТЕЛЬ, И СПОСОБ КУЛЬТИВИРОВАНИЯ С ИХ ПРИМЕНЕНИЕМ
US9321749B1 (en) 2012-07-25 2016-04-26 Globavir Biosciences, Inc. Heterocyclic compounds and uses thereof
CN104884064A (zh) 2012-12-24 2015-09-02 纽洛佳斯特拉斯公司 用于治疗胃肠道病症的方法
WO2015200369A1 (en) 2014-06-24 2015-12-30 Neurogastrx, Inc. Prodrugs of metopimazine
CN110876719B (zh) * 2018-09-06 2022-08-09 中国人民解放军军事科学院军事医学研究院 一种维生素k1注射剂及其制备方法
US10836757B1 (en) 2020-04-02 2020-11-17 Neurogastrx, Inc. Polymorphic forms of metopimazine

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DE575616C (de) * 1928-12-14 1933-04-29 Hans Much Dr Verfahren zur Herstellung bestaendiger, klarer, waessriger Loesungen von Lipoiden, Fetten oder Harzen
DE932083C (de) * 1954-03-31 1955-08-22 Upha Chem Pharm Praeparate G M Verfahren zur Herstellung stabiler waessriger Injektionsloesungen von 2-Methyl-5, 8-dimethoxy-furanochromon
US3044931A (en) * 1960-01-27 1962-07-17 Geigy Chem Corp Aryloxy acetic acid amides: process for parenteral application
NL126750C (it) * 1960-12-05
US3639597A (en) * 1968-02-02 1972-02-01 Merck & Co Inc Pharmaceutical compositions containing cholanic acid conjugates
GB1317184A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Steroid-containing pharmaceutical preparations
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
AU461715B2 (en) * 1972-01-21 1975-05-19 American Home Products Corporation Parenteral benzodiazepine compositions
US4017616A (en) * 1972-01-21 1977-04-12 American Home Products Corporation Parenteral benzodiazepine compositions
DE2315609A1 (de) * 1973-03-29 1974-10-17 Holzhueter Hermann Verfahren zum loesen von indomethacin in wasser und eine indomethacin enthaltende pharmazeutische zubereitung zur parenteralen applikation
DE2433173C3 (de) * 1974-07-10 1980-02-07 J. Pfrimmer & Co, 8520 Erlangen Verwendung von Cholansaurederivaten

Also Published As

Publication number Publication date
NZ184564A (en) 1979-12-11
HK26584A (en) 1984-03-30
IL52458A0 (en) 1977-10-31
FR2423219B1 (it) 1980-10-24
LU77708A1 (it) 1978-09-14
NL189072C (nl) 1993-01-04
DK149483C (da) 1986-12-15
AU517249B2 (en) 1981-07-16
MY8500263A (en) 1985-12-31
GB1587076A (en) 1981-03-25
NL7707641A (nl) 1978-01-16
JPS6051448B2 (ja) 1985-11-14
FR2358161B1 (it) 1980-07-25
NL189072B (nl) 1992-08-03
LU90037I2 (fr) 1997-06-13
US4158707A (en) 1979-06-19
AU2684677A (en) 1979-01-11
DE2730570A1 (de) 1978-01-19
IE771403L (en) 1978-01-12
SE448516B (sv) 1987-03-02
IL52458A (en) 1980-10-26
FR2358161A1 (fr) 1978-02-10
FR2423219A1 (fr) 1979-11-16
DK314777A (da) 1978-01-13
PH16333A (en) 1983-09-05
DK149483B (da) 1986-06-30
IE46037B1 (en) 1983-02-09
JPS539314A (en) 1978-01-27
CA1082596A (en) 1980-07-29
DE2730570C2 (it) 1989-01-19
SE7708059L (sv) 1978-01-13

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 176

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 176, 19920428; F. HOFFMANN-LA ROCHE AG.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960628