CY1117430T1 - Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη - Google Patents

Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη

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Publication number
CY1117430T1
CY1117430T1 CY20161100088T CY161100088T CY1117430T1 CY 1117430 T1 CY1117430 T1 CY 1117430T1 CY 20161100088 T CY20161100088 T CY 20161100088T CY 161100088 T CY161100088 T CY 161100088T CY 1117430 T1 CY1117430 T1 CY 1117430T1
Authority
CY
Cyprus
Prior art keywords
oxo
amino
methyl
methods
kinazolin
Prior art date
Application number
CY20161100088T
Other languages
Greek (el)
English (en)
Inventor
George W Muller
Peter H Schafer
Hon-Wah Man
Ling-Hua Zhang
Anita Gandhi
Rajesh Chopra
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of CY1117430T1 publication Critical patent/CY1117430T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Dermatology (AREA)
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  • Hematology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Rheumatology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
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CY20161100088T 2011-03-11 2016-02-02 Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη CY1117430T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161451995P 2011-03-11 2011-03-11
US201161480272P 2011-04-28 2011-04-28
EP12710836.3A EP2683384B1 (en) 2011-03-11 2012-03-09 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

Publications (1)

Publication Number Publication Date
CY1117430T1 true CY1117430T1 (el) 2017-04-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100088T CY1117430T1 (el) 2011-03-11 2016-02-02 Μεθοδοι θεραπειας καρκινου χρησιμοποιωντας 3-(5-αμινο-2-μεθυλ-4-οξο-4η-κιναζολιν-3-υλ)-πιπεριδινο-2,6-διονη

Country Status (29)

Country Link
US (6) US8906932B2 (pl)
EP (3) EP2683384B1 (pl)
JP (5) JP2014510078A (pl)
KR (2) KR20140019364A (pl)
CN (3) CN103561743A (pl)
AR (1) AR085651A1 (pl)
AU (4) AU2012229300B2 (pl)
BR (2) BR112013023280A2 (pl)
CA (2) CA2829593A1 (pl)
CY (1) CY1117430T1 (pl)
DK (1) DK2683384T3 (pl)
EA (2) EA201691939A1 (pl)
ES (2) ES2659205T3 (pl)
HK (1) HK1191858A1 (pl)
HR (1) HRP20160056T1 (pl)
HU (1) HUE027481T2 (pl)
IL (2) IL227990B (pl)
MX (2) MX2013010153A (pl)
NI (2) NI201300082A (pl)
PL (1) PL2683384T3 (pl)
PT (1) PT2683384E (pl)
RS (1) RS54553B1 (pl)
RU (3) RU2017120977A (pl)
SG (2) SG192947A1 (pl)
SI (1) SI2683384T1 (pl)
SM (1) SMT201600034B (pl)
TW (2) TWI542349B (pl)
WO (2) WO2012125475A1 (pl)
ZA (2) ZA201306148B (pl)

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JP6347782B2 (ja) * 2012-08-09 2018-06-27 セルジーン コーポレイション ３−（４−（（４−（モルホリノメチル）ベンジル）オキシ）−１−オキソイソインドリン−２−イル）ピペリジン−２，６−ジオンを使用する癌の治療方法
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JP6640126B2 (ja) 2014-06-27 2020-02-05 セルジーン コーポレイション セレブロン及び他のｅ３ユビキチンリガーゼの立体構造の変化を誘導するための組成物及び方法
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