CY1114072T1 - Ανασταλτικα πεπτιδια μετατρεπτικου ενζυμου αγγειοτασινης - Google Patents

Ανασταλτικα πεπτιδια μετατρεπτικου ενζυμου αγγειοτασινης

Info

Publication number
CY1114072T1
CY1114072T1 CY20131100344T CY131100344T CY1114072T1 CY 1114072 T1 CY1114072 T1 CY 1114072T1 CY 20131100344 T CY20131100344 T CY 20131100344T CY 131100344 T CY131100344 T CY 131100344T CY 1114072 T1 CY1114072 T1 CY 1114072T1
Authority
CY
Cyprus
Prior art keywords
tripeptides
inhibitory activity
ace
leu
val
Prior art date
Application number
CY20131100344T
Other languages
Greek (el)
English (en)
Inventor
Kyoichi Ogura
Taeko Iino
Sumio Asami
Original Assignee
Suntory Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Limited filed Critical Suntory Holdings Limited
Publication of CY1114072T1 publication Critical patent/CY1114072T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CY20131100344T 2003-03-18 2013-04-26 Ανασταλτικα πεπτιδια μετατρεπτικου ενζυμου αγγειοτασινης CY1114072T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003074488 2003-03-18
EP04721339A EP1605969B1 (en) 2003-03-18 2004-03-17 Angiotensin-converting enzyme inhibitory peptides

Publications (1)

Publication Number Publication Date
CY1114072T1 true CY1114072T1 (el) 2016-07-27

Family

ID=33027809

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100344T CY1114072T1 (el) 2003-03-18 2013-04-26 Ανασταλτικα πεπτιδια μετατρεπτικου ενζυμου αγγειοτασινης

Country Status (14)

Country Link
US (2) US7833985B2 (cg-RX-API-DMAC7.html)
EP (3) EP2145630B1 (cg-RX-API-DMAC7.html)
JP (3) JP4283848B2 (cg-RX-API-DMAC7.html)
KR (3) KR101077801B1 (cg-RX-API-DMAC7.html)
CN (1) CN100402089C (cg-RX-API-DMAC7.html)
AU (3) AU2004222435B2 (cg-RX-API-DMAC7.html)
CA (3) CA2526891C (cg-RX-API-DMAC7.html)
CY (1) CY1114072T1 (cg-RX-API-DMAC7.html)
DK (1) DK1605969T3 (cg-RX-API-DMAC7.html)
ES (3) ES2398788T3 (cg-RX-API-DMAC7.html)
PL (3) PL2145630T3 (cg-RX-API-DMAC7.html)
PT (1) PT1605969E (cg-RX-API-DMAC7.html)
TW (3) TWI328457B (cg-RX-API-DMAC7.html)
WO (1) WO2004082709A1 (cg-RX-API-DMAC7.html)

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AU2006239561B2 (en) * 2005-04-28 2010-09-16 Unilever Plc Peptides having a health benefit and compositions comprising them
ZA200708791B (en) * 2005-04-28 2009-08-26 Unilever Plc Peptides having an ace inhibiting effect
ATE453399T1 (de) * 2005-05-24 2010-01-15 Chr Hansen As Isolierte dipeptide mit ace-inhibitionseffekt
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CN101696233B (zh) * 2009-10-29 2012-02-01 吉林大学 蛋清蛋白血管紧张素转化酶抑制肽及其制备
JP5654290B2 (ja) * 2010-08-27 2015-01-14 ユニチカ株式会社 アンジオテンシン変換酵素阻害ペプチド及びその製造方法。
CN102399261B (zh) * 2010-09-07 2014-06-25 任发政 具有血管紧张素转化酶c-端选择性抑制活性的三肽及其应用和组合物
CN102475884B (zh) * 2010-11-29 2013-08-14 中国科学院大连化学物理研究所 四个多肽在制备ace抑制剂及降血压药物中的应用
CN102276690B (zh) * 2011-08-05 2013-03-20 成都中医药大学 降血压功能性多肽及其用途
JP6296722B2 (ja) * 2012-07-31 2018-03-20 サンスター株式会社 米糠酵素処理組成物
KR101481416B1 (ko) * 2012-10-17 2015-01-13 건국대학교 산학협력단 안지오텐신 전환 효소 저해 활성을 갖는 펩타이드
JP2014141462A (ja) * 2012-12-27 2014-08-07 Raffinee International Co Ltd ペプチド、並びに、アンジオテンシン変換酵素阻害剤、抗高血圧剤、及び飲食品
WO2014138304A1 (en) 2013-03-08 2014-09-12 Axiom Foods, Inc., Rice protein supplements
US9820504B2 (en) 2013-03-08 2017-11-21 Axiom Foods, Inc. Rice protein supplement and methods of use thereof
CN103172698B (zh) * 2013-04-10 2015-02-18 华东理工大学 降血压多肽
CN103242430B (zh) * 2013-05-31 2014-10-08 南京中医药大学 血管紧张素转化酶抑制肽及其制备方法和应用
CN103290086B (zh) * 2013-06-25 2015-01-14 广州合诚实业有限公司 具有ace抑制活性的绿豆蛋白肽及其制备方法与应用
CN104558110B (zh) * 2013-10-21 2018-06-08 中国科学院大连化学物理研究所 具有ace抑制活性的多肽及其在降血压药物中的应用
CN104558109B (zh) * 2013-10-21 2018-06-08 中国科学院大连化学物理研究所 源于油菜花粉的具有ace抑制活性的多肽化合物及应用
CN104447948B (zh) * 2014-11-25 2017-12-08 肽能九号生物科技有限公司 一种从荠菜中分离获得的降血压多肽
EP3473640B1 (en) * 2016-06-16 2020-06-24 Sunstar Inc. Novel tripeptide
CN106188227B (zh) * 2016-07-07 2019-09-24 华东理工大学 降血压肽和降血压蛋白质及其应用
CN110868870A (zh) 2017-05-12 2020-03-06 艾斯姆食品公司 大米产物及制备它们的系统和方法
WO2019006954A1 (zh) * 2017-07-07 2019-01-10 广州世优生物科技有限公司 含硫二肽在制备降血压药物或保健品中的应用
CN110498833B (zh) * 2019-08-30 2021-01-15 华南理工大学 一种具有ace抑制作用的三肽及其应用
JP7626766B2 (ja) * 2019-12-09 2025-02-04 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 飲料ペースト
JP7391738B2 (ja) * 2020-03-19 2023-12-05 Ｋｉｓｃｏ株式会社 ペプチド、及び苦味付与剤
CN111548387B (zh) * 2020-03-31 2020-12-18 华南农业大学 一种具有降血压功效的寡肽及其制备方法与应用
CN111471086B (zh) * 2020-04-16 2023-01-24 河南省农业科学院 芝麻多肽及其制备方法和应用
CN111825754B (zh) * 2020-07-16 2022-02-11 河南省农业科学院 一种从芝麻蛋白中获得的具有降血压与降血糖活性的多肽
JP7787424B2 (ja) * 2021-02-04 2025-12-17 ユーハ味覚糖株式会社 デプレスタチン含有組成物の製造方法
CN120904281B (zh) * 2025-08-05 2025-12-23 北京雯茵生物科技有限公司 生物活性肽及其在治疗心脑血管疾病中的应用

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Also Published As

Publication number Publication date
KR101077801B1 (ko) 2011-10-28
KR101119449B1 (ko) 2012-03-16
JP4283848B2 (ja) 2009-06-24
PL1605969T3 (pl) 2013-06-28
KR20050111778A (ko) 2005-11-28
EP2145630B1 (en) 2013-01-09
EP1605969B1 (en) 2013-02-13
CA2743313A1 (en) 2004-09-30
EP1938832B1 (en) 2013-02-13
CN100402089C (zh) 2008-07-16
ES2400308T3 (es) 2013-04-09
AU2004222435B2 (en) 2009-12-17
TWI411441B (zh) 2013-10-11
CN1780639A (zh) 2006-05-31
KR101078628B1 (ko) 2011-11-01
EP2145630A2 (en) 2010-01-20
AU2009236033A1 (en) 2009-12-03
TW201125574A (en) 2011-08-01
US7943578B2 (en) 2011-05-17
JP4369986B2 (ja) 2009-11-25
JP2009084294A (ja) 2009-04-23
TW200902053A (en) 2009-01-16
US20090318368A1 (en) 2009-12-24
EP1938832A1 (en) 2008-07-02
CA2743539A1 (en) 2004-09-30
TW200507871A (en) 2005-03-01
KR20110015674A (ko) 2011-02-16
JP2009084295A (ja) 2009-04-23
WO2004082709A1 (en) 2004-09-30
KR20110015675A (ko) 2011-02-16
CA2743313C (en) 2013-08-13
TWI328457B (en) 2010-08-11
JP2006520809A (ja) 2006-09-14
AU2009236033B2 (en) 2012-04-26
CA2526891A1 (en) 2004-09-30
US7833985B2 (en) 2010-11-16
AU2009236034A1 (en) 2009-12-03
CA2743539C (en) 2013-08-13
DK1605969T3 (da) 2013-04-29
AU2009236034B2 (en) 2012-04-26
PL1938832T3 (pl) 2013-06-28
PL2145630T3 (pl) 2013-04-30
US20060276627A1 (en) 2006-12-07
CA2526891C (en) 2013-08-13
JP4369985B2 (ja) 2009-11-25
ES2398788T3 (es) 2013-03-21
HK1084604A1 (en) 2006-08-04
TWI344371B (en) 2011-07-01
EP1605969A1 (en) 2005-12-21
EP2145630A3 (en) 2010-02-17
PT1605969E (pt) 2013-03-27
ES2400561T3 (es) 2013-04-10
AU2004222435A1 (en) 2004-09-30

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