CY1113005T1 - Διμερες ή τριμερες επιγαλλοκατεχινης με ανασταλτικη δραση στη λιπαση και/ή αντιοξειδωτικη δραση - Google Patents

Διμερες ή τριμερες επιγαλλοκατεχινης με ανασταλτικη δραση στη λιπαση και/ή αντιοξειδωτικη δραση

Info

Publication number
CY1113005T1
CY1113005T1 CY20121100503T CY121100503T CY1113005T1 CY 1113005 T1 CY1113005 T1 CY 1113005T1 CY 20121100503 T CY20121100503 T CY 20121100503T CY 121100503 T CY121100503 T CY 121100503T CY 1113005 T1 CY1113005 T1 CY 1113005T1
Authority
CY
Cyprus
Prior art keywords
lipase
activity
incorporated
meal
beverage
Prior art date
Application number
CY20121100503T
Other languages
English (en)
Inventor
Masaaki Nakai
Yuko Fukui
Sumio Asami
Original Assignee
Suntory Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Limited filed Critical Suntory Holdings Limited
Publication of CY1113005T1 publication Critical patent/CY1113005T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Birds (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Tea And Coffee (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Σκοπός της εν λόγω εφεύρεσης είναι να παρέχει αναστολέα της δράσης της λιπάσης που να παρουσιάζει ισχυρή ανασταλτική δράση ενάντια στην παγκρεατική λιπάση για τη μείωση της απορρόφησης λίπους από την κατανάλωση τροφίμων και/ή το οποίο να βοηθά στη μείωση και την πρόληψη της παχυσαρκίας, καθώς και παραγωγή τροφίμων ή ροφημάτων που να περιέχουν έναν τέτοιο αναστολέα της δράσης της λιπάσης. Άλλος στόχος της εφεύρεσης είναι η παροχή αναστολέα της λιπάσης που να προέρχεται από το τσάι, να ικανοποιεί το γευστικό κριτήριο των περισσότερων καταναλωτών, και ο οποίος δεν θα αλλοιώνει τη γεύση του τροφίμου ή του ροφήματος, όταν προστίθεται σε αυτό. Άλλος ένας στόχος της εφεύρεσης είναι η παροχή μεθόδου για την παραγωγή αναστολέων της λιπάσης όπως περιγράφηκε παραπάνω. Άλλος στόχος της εφεύρεσης είναι να παράσχει αντιοξειδωτικούς παράγοντες. Για την πραγματοποίηση αυτών των στόχων, τα διμερή επιγαλλοκατεχίνης (ομοδισφλαβόνες oolong) ή τριμερή προστίθενται στα τρόφιμα ή στα ροφήματα. Κατά συνέπεια, μπορεί να μειωθεί η απορρόφηση του λίπους που προέρχεται από την κατανάλωση τροφίμων και, επιπλέον, επιτυγχάνεται αντιοξειδωτική δράση. Οι ενώσεις της εφεύρεσης μπορούν να παραχθούν με αντίδραση της επιγαλλοκατεχίνης γαλλικού εστέρα με φορμαλδεΰδη με την παρουσία ενός οξέος.
CY20121100503T 2004-05-27 2012-06-06 Διμερες ή τριμερες επιγαλλοκατεχινης με ανασταλτικη δραση στη λιπαση και/ή αντιοξειδωτικη δραση CY1113005T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004158463A JP4668553B2 (ja) 2004-05-27 2004-05-27 リパーゼ阻害活性および／または抗酸化活性を有するエピガロカテキン二量体および三量体
EP05743859A EP1754702B1 (en) 2004-05-27 2005-05-26 Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidative activity

Publications (1)

Publication Number Publication Date
CY1113005T1 true CY1113005T1 (el) 2016-04-13

Family

ID=35450819

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100503T CY1113005T1 (el) 2004-05-27 2012-06-06 Διμερες ή τριμερες επιγαλλοκατεχινης με ανασταλτικη δραση στη λιπαση και/ή αντιοξειδωτικη δραση

Country Status (15)

Country Link
US (2) US7989492B2 (el)
EP (1) EP1754702B1 (el)
JP (1) JP4668553B2 (el)
KR (2) KR101213519B1 (el)
CN (1) CN100471850C (el)
AT (1) ATE548362T1 (el)
CY (1) CY1113005T1 (el)
DK (1) DK1754702T3 (el)
ES (1) ES2380701T3 (el)
HK (1) HK1103406A1 (el)
PL (1) PL1754702T3 (el)
PT (1) PT1754702E (el)
SG (1) SG186039A1 (el)
TW (1) TW200538146A (el)
WO (1) WO2005116005A1 (el)

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JP5563753B2 (ja) * 2008-08-29 2014-07-30 サントリーホールディングス株式会社 エピガロカテキンガレート重合体を有効成分とするグルコシルトランスフェラーゼ阻害剤
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JP7061303B2 (ja) * 2016-08-10 2022-04-28 国立大学法人九州大学 ６７ｋＤａラミニンレセプター活性化剤及びその使用
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KR102267472B1 (ko) * 2018-10-24 2021-06-21 전남대학교산학협력단 녹차 카테킨을 포함하는 중성지방 저감용 식품 조성물, 대사성 질환 개선용 식품 조성물 및 대사성 질환 예방 또는 치료용 약학 조성물
KR102672903B1 (ko) 2018-11-06 2024-06-10 (주)아모레퍼시픽 테아시넨신 a를 포함하는 화장료 조성물
KR102172267B1 (ko) * 2018-12-14 2020-10-30 한국기초과학지원연구원 에피갈로카테킨 갈레이트 이량체, 이의 제조방법 및 이를 이용한 화장료 조성물
TW202038742A (zh) * 2018-12-27 2020-11-01 日商花王股份有限公司 飲料及飲料用粉末食品
KR102238695B1 (ko) * 2019-03-29 2021-04-09 대구대학교 산학협력단 감마선 조사된 감탄닌을 유효성분으로 함유하는 피부 미백용 조성물
KR102221248B1 (ko) * 2019-08-05 2021-03-03 대구대학교 산학협력단 플라즈마 처리된 카테킨 유래 신규 화합물 및 이를 유효성분으로 함유하는 항비만용 조성물
KR102379821B1 (ko) * 2020-04-28 2022-03-30 한국핵융합에너지연구원 에피갈로카테킨 갈레이트 및 플로로글루시놀 혼합물에 플라즈마 처리하여 획득한 신규 화합물을 유효성분으로 함유하는 항비만용 조성물
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Also Published As

Publication number Publication date
US20110124887A1 (en) 2011-05-26
KR20070023758A (ko) 2007-02-28
US8309745B2 (en) 2012-11-13
US7989492B2 (en) 2011-08-02
HK1103406A1 (en) 2007-12-21
KR20110016507A (ko) 2011-02-17
EP1754702A4 (en) 2009-01-07
PL1754702T3 (pl) 2012-07-31
KR101077802B1 (ko) 2011-10-28
JP2005336117A (ja) 2005-12-08
US20080275258A1 (en) 2008-11-06
TW200538146A (en) 2005-12-01
TWI349548B (el) 2011-10-01
EP1754702B1 (en) 2012-03-07
CN100471850C (zh) 2009-03-25
SG186039A1 (en) 2012-12-28
CN1989123A (zh) 2007-06-27
ATE548362T1 (de) 2012-03-15
DK1754702T3 (da) 2012-05-21
PT1754702E (pt) 2012-04-12
KR101213519B1 (ko) 2012-12-18
EP1754702A1 (en) 2007-02-21
ES2380701T3 (es) 2012-05-17
WO2005116005A1 (ja) 2005-12-08
JP4668553B2 (ja) 2011-04-13

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