CY1110074T1 - Ενωσεις βενζιμιδαζολιου - Google Patents
Ενωσεις βενζιμιδαζολιουInfo
- Publication number
- CY1110074T1 CY1110074T1 CY20101100543T CY101100543T CY1110074T1 CY 1110074 T1 CY1110074 T1 CY 1110074T1 CY 20101100543 T CY20101100543 T CY 20101100543T CY 101100543 T CY101100543 T CY 101100543T CY 1110074 T1 CY1110074 T1 CY 1110074T1
- Authority
- CY
- Cyprus
- Prior art keywords
- gastric acid
- petrol
- compounds
- inhibitory effect
- effect against
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Αντικείμενο της παρούσας εφεύρεσης είναι να παρέχει μία νέα χημική ένωση χρήσιμη ως θεραπευτικό ή προφυλακτικό παράγοντα για οξεο-συναφείς νόσους, που έχει εξαιρετικό ανασταλτικό αποτέλεσμα έναντι έκκρισης γαστρικού οξέος, εξαιρετικό αποτέλεσμα διατήρησης του ανασταλτικού αποτελέσματος έναντι έκκρισης γαστρικού οξέος, διατηρώντας με τον τρόπο αυτό ενδογαστρικό pΗ υψηλό για μεγάλο χρόνο και που έχει περισσότερο ασφαλή και κατάλληλη φυσικοχημική σταθερότητα. Παρεχόμενη είναι μία ένωση που αντιπροσωπεύεται από
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005117643 | 2005-04-15 | ||
US67584805P | 2005-04-29 | 2005-04-29 | |
EP06731998A EP1870409B1 (en) | 2005-04-15 | 2006-04-17 | Benzimidazole compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110074T1 true CY1110074T1 (el) | 2015-01-14 |
Family
ID=37115157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100543T CY1110074T1 (el) | 2005-04-15 | 2010-06-11 | Ενωσεις βενζιμιδαζολιου |
Country Status (23)
Country | Link |
---|---|
US (3) | US20070015782A1 (el) |
EP (1) | EP1870409B1 (el) |
JP (1) | JP4949246B2 (el) |
KR (1) | KR101285696B1 (el) |
AU (1) | AU2006237974B2 (el) |
BR (1) | BRPI0608400B8 (el) |
CA (1) | CA2602610C (el) |
CY (1) | CY1110074T1 (el) |
DE (1) | DE602006014261D1 (el) |
DK (1) | DK1870409T3 (el) |
ES (1) | ES2344467T3 (el) |
HK (1) | HK1117826A1 (el) |
HR (1) | HRP20100389T1 (el) |
IL (1) | IL186282A (el) |
ME (1) | ME01855B (el) |
NO (1) | NO339502B1 (el) |
NZ (1) | NZ561920A (el) |
PL (1) | PL1870409T3 (el) |
PT (1) | PT1870409E (el) |
RS (1) | RS51389B (el) |
RU (1) | RU2409573C2 (el) |
SI (1) | SI1870409T1 (el) |
WO (1) | WO2006112442A1 (el) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070015782A1 (en) * | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
JP5492417B2 (ja) * | 2006-10-13 | 2014-05-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 胃酸分泌抑制作用を有するベンズイミダゾール化合物 |
JP2009196894A (ja) * | 2006-10-13 | 2009-09-03 | Eisai R & D Management Co Ltd | スルフィニルベンズイミダゾール化合物またはその塩の製造方法 |
TWI460182B (zh) * | 2007-04-11 | 2014-11-11 | Daiichi Sankyo Co Ltd | 原酸酯之製造方法 |
SI2071986T1 (sl) | 2007-12-18 | 2012-04-30 | Nestec Sa | Sistem za pripravo napitka iz sestavin, podprt s kodiranim vloĹľkom |
EP2588467A1 (en) | 2010-07-01 | 2013-05-08 | Amgen Inc. | Heterocyclic compounds and their use as inhibitors of pi3k activity |
DK2894151T3 (da) | 2012-09-04 | 2021-01-11 | Shanghai hengrui pharmaceutical co ltd | Imidazolinderivater, fremgangsmåder til fremstilling deraf og anvendelse deraf i medicin |
EP2803666B1 (de) | 2013-05-17 | 2016-04-27 | Symrise AG | Cyclische Acetale und Ketale sowie deren Verwendung als Riechstoff |
JP6377334B2 (ja) * | 2013-10-25 | 2018-08-22 | 東洋鋼鈑株式会社 | 非線形光学色素、フォトリフラクティブ材料組成物、フォトリフラクティブ基材およびホログラム記録媒体 |
CN107428726B (zh) * | 2014-12-26 | 2021-03-16 | 国立大学法人东京大学 | 光学活性的质子泵抑制剂化合物的制备方法 |
US10544113B2 (en) | 2016-03-07 | 2020-01-28 | National Health Research Institute | Thiazolidinone compounds and use thereof |
CN112457175B (zh) * | 2020-11-03 | 2022-09-02 | 山东师范大学 | 一种制备1,3-二苄氧基-2-丙酮的方法 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
EP0187977B1 (en) | 1984-12-18 | 1990-08-29 | Otsuka Pharmaceutical Co., Ltd. | Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same |
JPS62277322A (ja) | 1986-02-13 | 1987-12-02 | Takeda Chem Ind Ltd | 安定化された腸溶性抗潰瘍固形組成物 |
JPS62207271A (ja) | 1986-03-06 | 1987-09-11 | Yamanouchi Pharmaceut Co Ltd | 2−ピリジルメチルチオ基または2−ピリジルメチルスルフイニル基で置換された縮合環化合物 |
GB2189699A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
JPH0643426B2 (ja) | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
US5026560A (en) | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
JPH0222273A (ja) * | 1987-07-21 | 1990-01-25 | Yoshitomi Pharmaceut Ind Ltd | ピリジン化合物およびその医薬用途 |
JPH0633261B2 (ja) | 1988-01-22 | 1994-05-02 | 東京田辺製薬株式会社 | 新規なイミダゾ[4,5−bピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
SE9002206D0 (sv) * | 1990-06-20 | 1990-06-20 | Haessle Ab | New compounds |
CA2083606C (en) * | 1990-06-20 | 2001-08-21 | Arne Elof Brandstrom | Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use |
JP2820829B2 (ja) | 1991-03-07 | 1998-11-05 | 武田薬品工業株式会社 | 有核散剤およびその製造方法 |
JPH05117268A (ja) * | 1991-10-22 | 1993-05-14 | Yoshitomi Pharmaceut Ind Ltd | ピリジン化合物 |
JPH05177268A (ja) | 1992-01-09 | 1993-07-20 | Amada Co Ltd | 縦型パンチプレス |
AU746084B2 (en) | 1998-04-17 | 2002-04-11 | Taisho Pharmaceutical Co., Ltd. | Multiple-unit sustained release tablets |
CN100396675C (zh) | 1998-08-10 | 2008-06-25 | 加利福尼亚州大学董事会 | 质子泵抑制剂的前药 |
TW404832B (en) | 1999-01-27 | 2000-09-11 | Nang Kuang Pharmaceutical Co L | The oral medicine with good stability cotaining the omeprazole or the analogues |
WO2000050037A1 (en) | 1999-02-26 | 2000-08-31 | Nitromed, Inc. | Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use |
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
ES2168043B1 (es) | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
US20020064555A1 (en) * | 2000-09-29 | 2002-05-30 | Dan Cullen | Proton pump inhibitor formulation |
JP4331930B2 (ja) | 2001-10-17 | 2009-09-16 | 武田薬品工業株式会社 | 酸に不安定な薬物の高含量顆粒 |
PT2258351E (pt) | 2001-10-17 | 2013-07-29 | Takeda Pharmaceutical | Grânulos contendo lansoprazole em grande quantidade |
JP2003137771A (ja) | 2001-10-30 | 2003-05-14 | Nichiko Pharmaceutical Co Ltd | 難溶性薬物用医薬製剤 |
MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
US20040166162A1 (en) | 2003-01-24 | 2004-08-26 | Robert Niecestro | Novel pharmaceutical formulation containing a proton pump inhibitor and an antacid |
CA2518780C (en) * | 2003-03-12 | 2014-05-13 | Takeda Pharmaceutical Company Limited | Drug composition having active ingredient adhered at high concentration to spherical core |
US20060165793A1 (en) | 2003-08-04 | 2006-07-27 | Koji Ukai | Pharmaceutical preparation to be dispersed before administration |
US20070015782A1 (en) * | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
-
2006
- 2006-04-14 US US11/403,815 patent/US20070015782A1/en not_active Abandoned
- 2006-04-17 PT PT06731998T patent/PT1870409E/pt unknown
- 2006-04-17 SI SI200630712T patent/SI1870409T1/sl unknown
- 2006-04-17 AU AU2006237974A patent/AU2006237974B2/en active Active
- 2006-04-17 CA CA2602610A patent/CA2602610C/en active Active
- 2006-04-17 RU RU2007138053/04A patent/RU2409573C2/ru active
- 2006-04-17 PL PL06731998T patent/PL1870409T3/pl unknown
- 2006-04-17 JP JP2007528143A patent/JP4949246B2/ja active Active
- 2006-04-17 BR BRPI0608400A patent/BRPI0608400B8/pt active IP Right Grant
- 2006-04-17 DE DE602006014261T patent/DE602006014261D1/de active Active
- 2006-04-17 WO PCT/JP2006/308069 patent/WO2006112442A1/ja active Application Filing
- 2006-04-17 NZ NZ561920A patent/NZ561920A/en not_active IP Right Cessation
- 2006-04-17 ME MEP-2010-346A patent/ME01855B/me unknown
- 2006-04-17 DK DK06731998.8T patent/DK1870409T3/da active
- 2006-04-17 KR KR1020077023561A patent/KR101285696B1/ko active IP Right Grant
- 2006-04-17 ES ES06731998T patent/ES2344467T3/es active Active
- 2006-04-17 EP EP06731998A patent/EP1870409B1/en active Active
- 2006-04-17 RS RSP-2010/0346A patent/RS51389B/en unknown
- 2006-09-14 US US11/520,838 patent/US7425634B2/en active Active
-
2007
- 2007-09-25 IL IL186282A patent/IL186282A/en active IP Right Grant
- 2007-11-15 NO NO20075904A patent/NO339502B1/no not_active IP Right Cessation
-
2008
- 2008-07-17 HK HK08107942.6A patent/HK1117826A1/xx not_active IP Right Cessation
- 2008-08-11 US US12/189,590 patent/US8124780B2/en not_active Expired - Fee Related
-
2010
- 2010-06-11 CY CY20101100543T patent/CY1110074T1/el unknown
- 2010-07-15 HR HR20100389T patent/HRP20100389T1/hr unknown
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