CY1108001T1 - Παραγωγα μερικα αποθειωμενων γλυκοζαμινογλυκανων προικισμενα με αντι-αγγειογονο δραστηριοτητα και χωρις αντιπηκτικη επιδραση - Google Patents

Παραγωγα μερικα αποθειωμενων γλυκοζαμινογλυκανων προικισμενα με αντι-αγγειογονο δραστηριοτητα και χωρις αντιπηκτικη επιδραση

Info

Publication number
CY1108001T1
CY1108001T1 CY20071100140T CY071100140T CY1108001T1 CY 1108001 T1 CY1108001 T1 CY 1108001T1 CY 20071100140 T CY20071100140 T CY 20071100140T CY 071100140 T CY071100140 T CY 071100140T CY 1108001 T1 CY1108001 T1 CY 1108001T1
Authority
CY
Cyprus
Prior art keywords
glossamin
glycanes
producers
produced
effects
Prior art date
Application number
CY20071100140T
Other languages
English (en)
Inventor
Benito Casu
Giangiacomo Torri
Anna Maria Naggi
Giuseppe Giannini
Claudio Pisano
Sergio Penco
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of CY1108001T1 publication Critical patent/CY1108001T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Μερικώς αποθειωμένα παράγωγα γλυκοζαμινογλυκάνης παράγωγα περιγράφονται, συγκεκριμένα η ηπαρίνη, και περισσότερο συγκεκριμένα ενώσεις του τύπου (I), όπου οι ομάδες U, R και R1 έχουν τις έννοιες που υποδηλώνονται στην περιγραφή. Τα εν λόγω παράγωγα γλυκοζαμινογλυκάνης είναι προικισμένα με αντί-αγγείο- γόνο δραστηριότητα και είναι απαλλαγμένα αντιπηκτικής δραστηριότητας.
CY20071100140T 2000-01-25 2007-02-01 Παραγωγα μερικα αποθειωμενων γλυκοζαμινογλυκανων προικισμενα με αντι-αγγειογονο δραστηριοτητα και χωρις αντιπηκτικη επιδραση CY1108001T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000041A IT1316986B1 (it) 2000-01-25 2000-01-25 Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
EP01906098A EP1268558B1 (en) 2000-01-25 2001-01-24 Derivatives of partially desulphated glycosaminoglycans endowed with antiangiogenic activity and devoid of anticoagulating effect

Publications (1)

Publication Number Publication Date
CY1108001T1 true CY1108001T1 (el) 2013-09-04

Family

ID=11454382

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100140T CY1108001T1 (el) 2000-01-25 2007-02-01 Παραγωγα μερικα αποθειωμενων γλυκοζαμινογλυκανων προικισμενα με αντι-αγγειογονο δραστηριοτητα και χωρις αντιπηκτικη επιδραση

Country Status (22)

Country Link
US (4) US20030013682A1 (el)
EP (1) EP1268558B1 (el)
JP (1) JP5371167B2 (el)
KR (1) KR100812406B1 (el)
CN (1) CN100540570C (el)
AT (1) ATE348115T1 (el)
AU (1) AU782632B2 (el)
BR (1) BR0107696A (el)
CA (1) CA2397964C (el)
CY (1) CY1108001T1 (el)
CZ (1) CZ303030B6 (el)
DE (1) DE60125154T2 (el)
DK (1) DK1268558T3 (el)
ES (1) ES2277911T3 (el)
HK (1) HK1051867A1 (el)
HU (1) HU229509B1 (el)
IT (1) IT1316986B1 (el)
MX (1) MXPA02007195A (el)
PL (1) PL209479B1 (el)
PT (1) PT1268558E (el)
SK (1) SK287566B6 (el)
WO (1) WO2001055221A1 (el)

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Also Published As

Publication number Publication date
CZ303030B6 (cs) 2012-03-07
DK1268558T3 (da) 2007-04-10
ATE348115T1 (de) 2007-01-15
CA2397964A1 (en) 2001-08-02
US20100298263A1 (en) 2010-11-25
HK1051867A1 (en) 2003-08-22
CN100540570C (zh) 2009-09-16
MXPA02007195A (es) 2003-01-28
DE60125154T2 (de) 2007-10-25
HUP0204196A2 (hu) 2003-03-28
US8222231B2 (en) 2012-07-17
KR20020080381A (ko) 2002-10-23
ITRM20000041A0 (it) 2000-01-25
US20030013682A1 (en) 2003-01-16
KR100812406B1 (ko) 2008-03-11
AU782632B2 (en) 2005-08-18
PL357209A1 (en) 2004-07-26
CA2397964C (en) 2010-10-12
JP2003523460A (ja) 2003-08-05
WO2001055221A1 (en) 2001-08-02
DE60125154D1 (de) 2007-01-25
ES2277911T3 (es) 2007-08-01
ITRM20000041A1 (it) 2001-07-25
IT1316986B1 (it) 2003-05-26
EP1268558A1 (en) 2003-01-02
US20050107331A1 (en) 2005-05-19
JP5371167B2 (ja) 2013-12-18
HUP0204196A3 (en) 2003-05-28
SK287566B6 (sk) 2011-02-04
HU229509B1 (en) 2014-01-28
SK10672002A3 (sk) 2002-12-03
PL209479B1 (pl) 2011-09-30
CZ20022308A3 (cs) 2003-01-15
AU3406401A (en) 2001-08-07
BR0107696A (pt) 2002-10-15
US7790700B2 (en) 2010-09-07
US20050222084A1 (en) 2005-10-06
EP1268558B1 (en) 2006-12-13
CN1396930A (zh) 2003-02-12
PT1268558E (pt) 2007-02-28

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