IT1296998B1 - Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d - Google Patents

Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d

Info

Publication number
IT1296998B1
IT1296998B1 IT97MI002835A ITMI972835A IT1296998B1 IT 1296998 B1 IT1296998 B1 IT 1296998B1 IT 97MI002835 A IT97MI002835 A IT 97MI002835A IT MI972835 A ITMI972835 A IT MI972835A IT 1296998 B1 IT1296998 B1 IT 1296998B1
Authority
IT
Italy
Prior art keywords
molecular weight
average molecular
composition made
reproducible characteristics
heparin fractions
Prior art date
Application number
IT97MI002835A
Other languages
English (en)
Inventor
Ambrosi Luigi De
Sergio Gonella
Original Assignee
Derivati Organici Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Derivati Organici Lab filed Critical Derivati Organici Lab
Priority to IT97MI002835A priority Critical patent/IT1296998B1/it
Priority to US09/213,538 priority patent/US20020010152A1/en
Publication of ITMI972835A1 publication Critical patent/ITMI972835A1/it
Application granted granted Critical
Publication of IT1296998B1 publication Critical patent/IT1296998B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT97MI002835A 1997-12-19 1997-12-19 Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d IT1296998B1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT97MI002835A IT1296998B1 (it) 1997-12-19 1997-12-19 Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d
US09/213,538 US20020010152A1 (en) 1997-12-19 1998-12-17 Composition consisting of heparin fractions having reproducible characteristics with average molecular weight equal to 5200d

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002835A IT1296998B1 (it) 1997-12-19 1997-12-19 Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d

Publications (2)

Publication Number Publication Date
ITMI972835A1 ITMI972835A1 (it) 1999-06-19
IT1296998B1 true IT1296998B1 (it) 1999-08-03

Family

ID=11378419

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI002835A IT1296998B1 (it) 1997-12-19 1997-12-19 Composizione costituita da frazioni di eparina avente caratteristiche riproducibili con peso molecolare medio di 5200 d

Country Status (2)

Country Link
US (1) US20020010152A1 (it)
IT (1) IT1296998B1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7781416B2 (en) * 2000-01-25 2010-08-24 Sigma-Tau Research Switzerland S.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
IT1316986B1 (it) * 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
US20080139503A1 (en) * 2000-01-25 2008-06-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
ITMI20021372A1 (it) * 2002-06-21 2003-12-22 Derivati Organici Lab Processo per la depolimerizzazione fisica dei glicosamminogliacani e prodotti da esso ottenuti
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CN102585023B (zh) * 2012-01-03 2015-04-29 浙江大学 海参多糖的电离辐射降解法

Also Published As

Publication number Publication date
US20020010152A1 (en) 2002-01-24
ITMI972835A1 (it) 1999-06-19

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Legal Events

Date Code Title Description
0001 Granted