CS252476B2 - Method of benzofuranalkyl and benzothiophenylalkyl acids' new substituted derivatives production - Google Patents
Method of benzofuranalkyl and benzothiophenylalkyl acids' new substituted derivatives production Download PDFInfo
- Publication number
- CS252476B2 CS252476B2 CS845459A CS545984A CS252476B2 CS 252476 B2 CS252476 B2 CS 252476B2 CS 845459 A CS845459 A CS 845459A CS 545984 A CS545984 A CS 545984A CS 252476 B2 CS252476 B2 CS 252476B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- alkyl
- acid
- compound
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS856653A CS252494B2 (cs) | 1983-07-14 | 1985-09-18 | Způsob výroby nových substituovaných derivátů benzofuranalkylových a benzothiofenalkylových kyselin |
CS856652A CS252493B2 (cs) | 1983-07-14 | 1985-09-18 | Způsob výroby nových substituove^ých derivátů benzofuranalkylových a benzothiaofenalkylových kyselin |
CS856654A CS252495B2 (cs) | 1983-07-14 | 1985-09-18 | Způsob výroby nových substituovaných derivátů benzofuranalkylových a benzothiofenalkylových kyselin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51354583A | 1983-07-14 | 1983-07-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
CS545984A2 CS545984A2 (en) | 1987-01-15 |
CS252476B2 true CS252476B2 (en) | 1987-09-17 |
Family
ID=24043724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS845459A CS252476B2 (en) | 1983-07-14 | 1984-07-13 | Method of benzofuranalkyl and benzothiophenylalkyl acids' new substituted derivatives production |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0132130B1 (da) |
JP (1) | JPS6038376A (da) |
KR (1) | KR880002533B1 (da) |
AR (1) | AR240815A1 (da) |
AT (1) | ATE50769T1 (da) |
AU (1) | AU567953B2 (da) |
CA (1) | CA1241008A (da) |
CS (1) | CS252476B2 (da) |
DE (1) | DE3481512D1 (da) |
DK (1) | DK347484A (da) |
ES (2) | ES8604554A1 (da) |
FI (1) | FI842738A (da) |
GR (1) | GR79949B (da) |
HU (1) | HU200450B (da) |
IL (1) | IL72409A (da) |
NO (1) | NO842878L (da) |
NZ (1) | NZ208894A (da) |
PH (1) | PH20790A (da) |
PL (4) | PL146523B1 (da) |
PT (1) | PT78905B (da) |
SU (2) | SU1409130A3 (da) |
ZA (1) | ZA845445B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0226670B1 (en) * | 1985-12-04 | 1991-04-10 | Imperial Chemical Industries Plc | Process for hydroxyaraldehydes |
GB8825505D0 (en) | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
ES2301161T3 (es) * | 1994-07-27 | 2008-06-16 | Vanderbilt University | Compuestos de dihidrobenzofurano y compuestos relacionados utiles como agentes anti-inflamatorios. |
US5656661A (en) * | 1994-07-27 | 1997-08-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
GB9814801D0 (en) * | 1998-07-09 | 1998-09-09 | Univ Strathclyde | Integrin dependent cell adhesion inhibitors |
EP2177511A2 (en) | 2002-12-10 | 2010-04-21 | Ranbaxy Laboratories Limited | Process for preparing 3,6-disubstituted azabicyclo derivatives |
WO2023210740A1 (ja) * | 2022-04-28 | 2023-11-02 | 第一三共株式会社 | ベンゾチオフェン化合物 |
CN115403544B (zh) * | 2022-09-16 | 2024-05-31 | 台州永健医药科技有限公司 | 一种丹酚酸c的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2077733B1 (da) * | 1970-02-10 | 1973-03-16 | Roussel Uclaf | |
DE2909754A1 (de) * | 1979-03-13 | 1980-09-18 | Thomae Gmbh Dr K | Neue benzofuran- und benzothiophenderivate, deren herstellung und deren verwendung als arzneimittel |
US4237144A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans |
DE2931672A1 (de) * | 1979-08-04 | 1981-02-26 | Basf Ag | Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
JPS5951275A (ja) * | 1982-05-31 | 1984-03-24 | Sumitomo Chem Co Ltd | 新規な複素環化合物 |
EP0117675B1 (en) * | 1983-02-19 | 1986-07-23 | Beecham Group Plc | Benzofuran and benzothiophene-carboxylic-acid derivatives |
-
1984
- 1984-07-09 FI FI842738A patent/FI842738A/fi not_active Application Discontinuation
- 1984-07-13 CS CS845459A patent/CS252476B2/cs unknown
- 1984-07-13 IL IL72409A patent/IL72409A/xx unknown
- 1984-07-13 DK DK347484A patent/DK347484A/da not_active Application Discontinuation
- 1984-07-13 AT AT84304793T patent/ATE50769T1/de not_active IP Right Cessation
- 1984-07-13 NZ NZ208894A patent/NZ208894A/en unknown
- 1984-07-13 PL PL1984255163A patent/PL146523B1/pl unknown
- 1984-07-13 AR AR297217A patent/AR240815A1/es active
- 1984-07-13 ZA ZA845445A patent/ZA845445B/xx unknown
- 1984-07-13 HU HU842740A patent/HU200450B/hu not_active IP Right Cessation
- 1984-07-13 JP JP59146685A patent/JPS6038376A/ja active Pending
- 1984-07-13 CA CA000458906A patent/CA1241008A/en not_active Expired
- 1984-07-13 AU AU30593/84A patent/AU567953B2/en not_active Ceased
- 1984-07-13 PL PL1984248729A patent/PL145622B1/pl unknown
- 1984-07-13 KR KR1019840004126A patent/KR880002533B1/ko not_active IP Right Cessation
- 1984-07-13 ES ES534324A patent/ES8604554A1/es not_active Expired
- 1984-07-13 PT PT78905A patent/PT78905B/pt unknown
- 1984-07-13 SU SU843765004A patent/SU1409130A3/ru active
- 1984-07-13 PL PL1984255164A patent/PL146833B1/pl unknown
- 1984-07-13 EP EP84304793A patent/EP0132130B1/en not_active Expired - Lifetime
- 1984-07-13 PH PH30987A patent/PH20790A/en unknown
- 1984-07-13 DE DE8484304793T patent/DE3481512D1/de not_active Expired - Fee Related
- 1984-07-13 PL PL25516284A patent/PL255162A1/xx unknown
- 1984-07-13 GR GR75294A patent/GR79949B/el unknown
- 1984-07-13 NO NO842878A patent/NO842878L/no unknown
-
1985
- 1985-06-25 ES ES544539A patent/ES8607960A1/es not_active Expired
-
1986
- 1986-02-07 SU SU864024097A patent/SU1614762A3/ru active
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