DE3481512D1 - Aroylbenzofuran- und aroylbenzothiophenessigsaeuren und -propionsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents
Aroylbenzofuran- und aroylbenzothiophenessigsaeuren und -propionsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- DE3481512D1 DE3481512D1 DE8484304793T DE3481512T DE3481512D1 DE 3481512 D1 DE3481512 D1 DE 3481512D1 DE 8484304793 T DE8484304793 T DE 8484304793T DE 3481512 T DE3481512 T DE 3481512T DE 3481512 D1 DE3481512 D1 DE 3481512D1
- Authority
- DE
- Germany
- Prior art keywords
- acids
- aroylbenzothiophenic
- aroylbenzofuranic
- production
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51354583A | 1983-07-14 | 1983-07-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3481512D1 true DE3481512D1 (de) | 1990-04-12 |
Family
ID=24043724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484304793T Expired - Fee Related DE3481512D1 (de) | 1983-07-14 | 1984-07-13 | Aroylbenzofuran- und aroylbenzothiophenessigsaeuren und -propionsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0132130B1 (de) |
JP (1) | JPS6038376A (de) |
KR (1) | KR880002533B1 (de) |
AR (1) | AR240815A1 (de) |
AT (1) | ATE50769T1 (de) |
AU (1) | AU567953B2 (de) |
CA (1) | CA1241008A (de) |
CS (1) | CS252476B2 (de) |
DE (1) | DE3481512D1 (de) |
DK (1) | DK347484A (de) |
ES (2) | ES8604554A1 (de) |
FI (1) | FI842738A (de) |
GR (1) | GR79949B (de) |
HU (1) | HU200450B (de) |
IL (1) | IL72409A (de) |
NO (1) | NO842878L (de) |
NZ (1) | NZ208894A (de) |
PH (1) | PH20790A (de) |
PL (4) | PL146523B1 (de) |
PT (1) | PT78905B (de) |
SU (2) | SU1409130A3 (de) |
ZA (1) | ZA845445B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0226670B1 (de) * | 1985-12-04 | 1991-04-10 | Imperial Chemical Industries Plc | Herstellung von Hydroxyaraldehyden |
GB8825505D0 (en) | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
US5656661A (en) * | 1994-07-27 | 1997-08-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
EP0773939B1 (de) * | 1994-07-27 | 2008-02-06 | Vanderbilt University | Dihydrobenzofurane und verwandte verbindungen als entzündungshemmende mittel |
US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
GB9814801D0 (en) * | 1998-07-09 | 1998-09-09 | Univ Strathclyde | Integrin dependent cell adhesion inhibitors |
JP2006518707A (ja) | 2002-12-10 | 2006-08-17 | ランバクシー ラボラトリーズ リミテッド | ムスカリン様受容体アンタゴニストとしての3,6−二置換アザビシクロ[3.1.0]ヘキサン誘導体 |
WO2023210740A1 (ja) * | 2022-04-28 | 2023-11-02 | 第一三共株式会社 | ベンゾチオフェン化合物 |
CN115403544B (zh) * | 2022-09-16 | 2024-05-31 | 台州永健医药科技有限公司 | 一种丹酚酸c的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2077733B1 (de) * | 1970-02-10 | 1973-03-16 | Roussel Uclaf | |
DE2909754A1 (de) * | 1979-03-13 | 1980-09-18 | Thomae Gmbh Dr K | Neue benzofuran- und benzothiophenderivate, deren herstellung und deren verwendung als arzneimittel |
US4237144A (en) * | 1979-06-21 | 1980-12-02 | Merck & Co., Inc. | 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans |
DE2931672A1 (de) * | 1979-08-04 | 1981-02-26 | Basf Ag | Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
JPS5951275A (ja) * | 1982-05-31 | 1984-03-24 | Sumitomo Chem Co Ltd | 新規な複素環化合物 |
EP0117675B1 (de) * | 1983-02-19 | 1986-07-23 | Beecham Group Plc | Benzofuran- und Benzothiophencarbonsäurederivate |
-
1984
- 1984-07-09 FI FI842738A patent/FI842738A/fi not_active Application Discontinuation
- 1984-07-13 PT PT78905A patent/PT78905B/pt unknown
- 1984-07-13 NO NO842878A patent/NO842878L/no unknown
- 1984-07-13 KR KR1019840004126A patent/KR880002533B1/ko not_active IP Right Cessation
- 1984-07-13 PL PL1984255163A patent/PL146523B1/pl unknown
- 1984-07-13 PH PH30987A patent/PH20790A/en unknown
- 1984-07-13 GR GR75294A patent/GR79949B/el unknown
- 1984-07-13 CA CA000458906A patent/CA1241008A/en not_active Expired
- 1984-07-13 ES ES534324A patent/ES8604554A1/es not_active Expired
- 1984-07-13 AR AR297217A patent/AR240815A1/es active
- 1984-07-13 SU SU843765004A patent/SU1409130A3/ru active
- 1984-07-13 AU AU30593/84A patent/AU567953B2/en not_active Ceased
- 1984-07-13 ZA ZA845445A patent/ZA845445B/xx unknown
- 1984-07-13 DE DE8484304793T patent/DE3481512D1/de not_active Expired - Fee Related
- 1984-07-13 CS CS845459A patent/CS252476B2/cs unknown
- 1984-07-13 AT AT84304793T patent/ATE50769T1/de not_active IP Right Cessation
- 1984-07-13 EP EP84304793A patent/EP0132130B1/de not_active Expired - Lifetime
- 1984-07-13 PL PL1984255164A patent/PL146833B1/pl unknown
- 1984-07-13 DK DK347484A patent/DK347484A/da not_active Application Discontinuation
- 1984-07-13 JP JP59146685A patent/JPS6038376A/ja active Pending
- 1984-07-13 PL PL1984248729A patent/PL145622B1/pl unknown
- 1984-07-13 HU HU842740A patent/HU200450B/hu not_active IP Right Cessation
- 1984-07-13 NZ NZ208894A patent/NZ208894A/en unknown
- 1984-07-13 IL IL72409A patent/IL72409A/xx unknown
- 1984-07-13 PL PL25516284A patent/PL255162A1/xx unknown
-
1985
- 1985-06-25 ES ES544539A patent/ES8607960A1/es not_active Expired
-
1986
- 1986-02-07 SU SU864024097A patent/SU1614762A3/ru active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |