ZA845445B - Aroyl benzofuran and benzothiopene acetic and proionic acids - Google Patents

Aroyl benzofuran and benzothiopene acetic and proionic acids

Info

Publication number
ZA845445B
ZA845445B ZA845445A ZA845445A ZA845445B ZA 845445 B ZA845445 B ZA 845445B ZA 845445 A ZA845445 A ZA 845445A ZA 845445 A ZA845445 A ZA 845445A ZA 845445 B ZA845445 B ZA 845445B
Authority
ZA
South Africa
Prior art keywords
benzothiopene
proionic
aroyl
benzofuran
acetic
Prior art date
Application number
ZA845445A
Other languages
English (en)
Inventor
James Patrick Dunn
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA845445B publication Critical patent/ZA845445B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA845445A 1983-07-14 1984-07-13 Aroyl benzofuran and benzothiopene acetic and proionic acids ZA845445B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51354583A 1983-07-14 1983-07-14

Publications (1)

Publication Number Publication Date
ZA845445B true ZA845445B (en) 1986-02-26

Family

ID=24043724

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845445A ZA845445B (en) 1983-07-14 1984-07-13 Aroyl benzofuran and benzothiopene acetic and proionic acids

Country Status (22)

Country Link
EP (1) EP0132130B1 (da)
JP (1) JPS6038376A (da)
KR (1) KR880002533B1 (da)
AR (1) AR240815A1 (da)
AT (1) ATE50769T1 (da)
AU (1) AU567953B2 (da)
CA (1) CA1241008A (da)
CS (1) CS252476B2 (da)
DE (1) DE3481512D1 (da)
DK (1) DK347484A (da)
ES (2) ES8604554A1 (da)
FI (1) FI842738A (da)
GR (1) GR79949B (da)
HU (1) HU200450B (da)
IL (1) IL72409A (da)
NO (1) NO842878L (da)
NZ (1) NZ208894A (da)
PH (1) PH20790A (da)
PL (4) PL146523B1 (da)
PT (1) PT78905B (da)
SU (2) SU1409130A3 (da)
ZA (1) ZA845445B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226670B1 (en) * 1985-12-04 1991-04-10 Imperial Chemical Industries Plc Process for hydroxyaraldehydes
GB8825505D0 (en) 1988-11-01 1988-12-07 Pfizer Ltd Therapeutic agents
US5656661A (en) * 1994-07-27 1997-08-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
JPH10506615A (ja) * 1994-07-27 1998-06-30 ザ、プロクター、エンド、ギャンブル、カンパニー 抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
GB9814801D0 (en) * 1998-07-09 1998-09-09 Univ Strathclyde Integrin dependent cell adhesion inhibitors
EP1572648B1 (en) 2002-12-10 2008-07-09 Ranbaxy Laboratories, Ltd. 3,6-disubstituted azabicyclo (3.1.0)-hexane derivatives as muscarinic receptor antagonists
TW202345792A (zh) * 2022-04-28 2023-12-01 日商第一三共股份有限公司 苯并噻吩化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2077733B1 (da) * 1970-02-10 1973-03-16 Roussel Uclaf
DE2909754A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue benzofuran- und benzothiophenderivate, deren herstellung und deren verwendung als arzneimittel
US4237144A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans
DE2931672A1 (de) * 1979-08-04 1981-02-26 Basf Ag Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
JPS5951275A (ja) * 1982-05-31 1984-03-24 Sumitomo Chem Co Ltd 新規な複素環化合物
DE3460315D1 (en) * 1983-02-19 1986-08-28 Beecham Group Plc Benzofuran and benzothiophene-carboxylic-acid derivatives

Also Published As

Publication number Publication date
PL255163A1 (en) 1986-07-15
PT78905A (en) 1984-08-01
AU3059384A (en) 1985-01-17
PT78905B (en) 1986-07-22
CA1241008A (en) 1988-08-23
DK347484A (da) 1985-01-15
NO842878L (no) 1985-01-15
SU1409130A3 (ru) 1988-07-07
CS545984A2 (en) 1987-01-15
HUT36108A (en) 1985-08-28
EP0132130A2 (en) 1985-01-23
PL255162A1 (en) 1986-07-15
KR880002533B1 (ko) 1988-11-28
FI842738A (fi) 1985-01-15
PL255164A1 (en) 1986-07-15
AR240815A1 (es) 1991-02-28
PL248729A1 (en) 1986-06-17
AU567953B2 (en) 1987-12-10
CS252476B2 (en) 1987-09-17
IL72409A (en) 1988-05-31
EP0132130A3 (en) 1986-12-10
ATE50769T1 (de) 1990-03-15
PL146523B1 (en) 1989-02-28
ES544539A0 (es) 1986-06-16
NZ208894A (en) 1987-01-23
PH20790A (en) 1987-04-14
ES8607960A1 (es) 1986-06-16
GR79949B (da) 1984-10-31
JPS6038376A (ja) 1985-02-27
ES8604554A1 (es) 1986-02-16
DK347484D0 (da) 1984-07-13
SU1614762A3 (ru) 1990-12-15
ES534324A0 (es) 1986-02-16
EP0132130B1 (en) 1990-03-07
IL72409A0 (en) 1984-11-30
PL145622B1 (en) 1988-10-31
KR850001202A (ko) 1985-03-16
PL146833B1 (en) 1989-03-31
FI842738A0 (fi) 1984-07-09
HU200450B (en) 1990-06-28
AR240815A2 (es) 1991-02-28
DE3481512D1 (de) 1990-04-12

Similar Documents

Publication Publication Date Title
PH18663A (en) N-substituted-amido-amino acids
GR80278B (en) Azahomoerythromycin d derivative and intermediates therefor
PH18657A (en) Amido-amino acids
ZA845445B (en) Aroyl benzofuran and benzothiopene acetic and proionic acids
GB2095256B (en) Oxazaphosphorin-4-thio-alkanesulphonic acids
EP0114734A3 (en) Pyridinylmethylamino-arylic acids
DE3276311D1 (en) Octahydro-2-(omega-mercaptoalkanoyl)3-oxo-1h-isoindole-1-carboxylic acids and esters
GB8519658D0 (en) Carboxylic acids
EP0141319A3 (en) Substituted phenoxyalcanoic-acid ester
GB8432537D0 (en) Scanning
GB2157288B (en) Cyclopropane derivatives
GB8319619D0 (en) Acetic anhydride
GB8319184D0 (en) Carboxylic acids
ZA819028B (en) Acyloxyalkenoic acids and process therefor
GB8412495D0 (en) Aryloxybenzoic acids
GB8418958D0 (en) Aryloxybenzoic acids
GB8420298D0 (en) Intermediates and derivatives
IE832789L (en) Diphenylmethylideneamino alkanoic acids and derivatives¹thereof
IE832640L (en) Imidazolylbenzoquinolizines and related intermediates
IE830468L (en) 2-aminomethylphenols and related intermediates
GB8300888D0 (en) Carboxylic acids
GB8319358D0 (en) Process and intermediates
GB8311427D0 (en) Process and intermediates
IE820423L (en) 7-acylamino-3-cephem-4-carboxylic acids and related¹intermediates
IE841808L (en) Aroylbenzofuran and benzothiophene acetic and propionic¹acids