CS208800B2 - Method of making the new indole derivatives - Google Patents
Method of making the new indole derivatives Download PDFInfo
- Publication number
- CS208800B2 CS208800B2 CS801663A CS166380A CS208800B2 CS 208800 B2 CS208800 B2 CS 208800B2 CS 801663 A CS801663 A CS 801663A CS 166380 A CS166380 A CS 166380A CS 208800 B2 CS208800 B2 CS 208800B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- methyl
- indol
- group
- yloxy
- ethyl ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Photoreceptors In Electrophotography (AREA)
- Power Steering Mechanism (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792909779 DE2909779A1 (de) | 1979-03-13 | 1979-03-13 | Neue indolderivate, deren herstellung und deren verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
CS208800B2 true CS208800B2 (en) | 1981-09-15 |
Family
ID=6065240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS801663A CS208800B2 (en) | 1979-03-13 | 1980-03-11 | Method of making the new indole derivatives |
Country Status (21)
Country | Link |
---|---|
US (1) | US4343811A (no) |
EP (1) | EP0015523B1 (no) |
JP (1) | JPS55124758A (no) |
AT (1) | ATE1642T1 (no) |
AU (1) | AU5636880A (no) |
CA (1) | CA1142519A (no) |
CS (1) | CS208800B2 (no) |
DD (1) | DD149804A5 (no) |
DE (2) | DE2909779A1 (no) |
ES (3) | ES488446A1 (no) |
FI (1) | FI800770A (no) |
GR (1) | GR75241B (no) |
HU (1) | HU180126B (no) |
IL (1) | IL59598A0 (no) |
NO (1) | NO800709L (no) |
NZ (1) | NZ193111A (no) |
PL (1) | PL222634A1 (no) |
PT (1) | PT70921B (no) |
SU (1) | SU1028247A3 (no) |
YU (1) | YU68180A (no) |
ZA (1) | ZA801441B (no) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA814057B (en) * | 1980-06-18 | 1982-07-28 | May & Baker Ltd | Indole and indoline derivatives |
DE3232968A1 (de) * | 1981-09-10 | 1983-06-09 | Degussa Ag, 6000 Frankfurt | Neue 2-(hydroxy-phenyl)-indole und verfahren zu deren herstellung |
US4543360A (en) * | 1981-09-10 | 1985-09-24 | Degussa Aktiengesellschaft | 2-(Hydroxy-phenyl)-indoles and process for their production |
GB2111050B (en) * | 1981-11-19 | 1985-09-11 | Ciba Geigy Ag | N-substituted-2-pyridylindoles |
US4478842A (en) * | 1981-11-19 | 1984-10-23 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
US4460777A (en) * | 1981-11-19 | 1984-07-17 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
US4759923A (en) * | 1987-06-25 | 1988-07-26 | Hercules Incorporated | Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives |
DE69728688T2 (de) | 1996-11-19 | 2004-08-19 | Amgen Inc., Thousand Oaks | Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel |
US6103733A (en) * | 1998-09-09 | 2000-08-15 | Bachmann; Kenneth A. | Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes |
US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
MX2007000762A (es) | 2004-07-22 | 2007-04-02 | Ptc Therapeutics Inc | Tienopiridinas para tratamientode hepatitis c. |
DE102006053064A1 (de) * | 2006-11-08 | 2008-05-21 | Universität Potsdam | Verfahren zur Herstellung aromatischer Diazoniumsalze |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2237361A1 (de) * | 1972-07-29 | 1974-02-14 | Boehringer Mannheim Gmbh | (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben |
US4070470A (en) * | 1974-06-24 | 1978-01-24 | Otsuka Pharmaceutical Co., Ltd. | Platelet aggregation inhibiting carbostyrils, their compositions and method of use |
-
1979
- 1979-03-13 DE DE19792909779 patent/DE2909779A1/de not_active Withdrawn
-
1980
- 1980-02-11 ES ES488446A patent/ES488446A1/es not_active Expired
- 1980-02-12 SU SU802879303A patent/SU1028247A3/ru active
- 1980-02-19 GR GR61231A patent/GR75241B/el unknown
- 1980-02-29 US US06/126,006 patent/US4343811A/en not_active Expired - Lifetime
- 1980-03-03 AT AT80101037T patent/ATE1642T1/de not_active IP Right Cessation
- 1980-03-03 EP EP80101037A patent/EP0015523B1/de not_active Expired
- 1980-03-03 DE DE8080101037T patent/DE3060932D1/de not_active Expired
- 1980-03-10 DD DD80219568A patent/DD149804A5/de unknown
- 1980-03-10 PT PT70921A patent/PT70921B/pt unknown
- 1980-03-11 JP JP3083480A patent/JPS55124758A/ja active Pending
- 1980-03-11 CS CS801663A patent/CS208800B2/cs unknown
- 1980-03-12 PL PL22263480A patent/PL222634A1/xx unknown
- 1980-03-12 NO NO800709A patent/NO800709L/no unknown
- 1980-03-12 IL IL59598A patent/IL59598A0/xx unknown
- 1980-03-12 YU YU00681/80A patent/YU68180A/xx unknown
- 1980-03-12 HU HU8080591A patent/HU180126B/hu unknown
- 1980-03-12 ZA ZA00801441A patent/ZA801441B/xx unknown
- 1980-03-12 AU AU56368/80A patent/AU5636880A/en not_active Abandoned
- 1980-03-12 FI FI800770A patent/FI800770A/fi not_active Application Discontinuation
- 1980-03-12 CA CA000347485A patent/CA1142519A/en not_active Expired
- 1980-03-12 NZ NZ193111A patent/NZ193111A/xx unknown
- 1980-04-09 ES ES490380A patent/ES490380A0/es active Granted
- 1980-04-09 ES ES490379A patent/ES8101047A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT70921B (de) | 1981-06-24 |
ATE1642T1 (de) | 1982-10-15 |
ES8101048A1 (es) | 1980-12-01 |
ES488446A1 (es) | 1980-10-01 |
ES490379A0 (es) | 1980-12-01 |
SU1028247A3 (ru) | 1983-07-07 |
HU180126B (en) | 1983-02-28 |
YU68180A (en) | 1983-04-30 |
IL59598A0 (en) | 1980-06-30 |
DD149804A5 (de) | 1981-07-29 |
EP0015523B1 (de) | 1982-10-13 |
JPS55124758A (en) | 1980-09-26 |
EP0015523A1 (de) | 1980-09-17 |
PT70921A (de) | 1980-04-01 |
DE2909779A1 (de) | 1980-09-18 |
PL222634A1 (no) | 1980-12-01 |
AU5636880A (en) | 1980-09-18 |
ZA801441B (en) | 1981-11-25 |
NZ193111A (en) | 1983-04-12 |
FI800770A (fi) | 1980-09-14 |
GR75241B (no) | 1984-07-13 |
ES8101047A1 (es) | 1980-12-01 |
NO800709L (no) | 1980-09-15 |
CA1142519A (en) | 1983-03-08 |
US4343811A (en) | 1982-08-10 |
DE3060932D1 (en) | 1982-11-18 |
ES490380A0 (es) | 1980-12-01 |
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