ZA801441B - Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof - Google Patents

Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof

Info

Publication number
ZA801441B
ZA801441B ZA00801441A ZA801441A ZA801441B ZA 801441 B ZA801441 B ZA 801441B ZA 00801441 A ZA00801441 A ZA 00801441A ZA 801441 A ZA801441 A ZA 801441A ZA 801441 B ZA801441 B ZA 801441B
Authority
ZA
South Africa
Prior art keywords
indole derivatives
processes
preparation
pharmaceutical preparations
compounds
Prior art date
Application number
ZA00801441A
Other languages
English (en)
Inventor
G Griss
R Sauter
J Kaehling
W Grell
B Eisele
N Kaubisch
R Hurnaus
E Rupprecht
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA801441B publication Critical patent/ZA801441B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Power Steering Mechanism (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00801441A 1979-03-13 1980-03-12 Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof ZA801441B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792909779 DE2909779A1 (de) 1979-03-13 1979-03-13 Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA801441B true ZA801441B (en) 1981-11-25

Family

ID=6065240

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00801441A ZA801441B (en) 1979-03-13 1980-03-12 Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof

Country Status (21)

Country Link
US (1) US4343811A (xx)
EP (1) EP0015523B1 (xx)
JP (1) JPS55124758A (xx)
AT (1) ATE1642T1 (xx)
AU (1) AU5636880A (xx)
CA (1) CA1142519A (xx)
CS (1) CS208800B2 (xx)
DD (1) DD149804A5 (xx)
DE (2) DE2909779A1 (xx)
ES (3) ES488446A1 (xx)
FI (1) FI800770A (xx)
GR (1) GR75241B (xx)
HU (1) HU180126B (xx)
IL (1) IL59598A0 (xx)
NO (1) NO800709L (xx)
NZ (1) NZ193111A (xx)
PL (1) PL222634A1 (xx)
PT (1) PT70921B (xx)
SU (1) SU1028247A3 (xx)
YU (1) YU68180A (xx)
ZA (1) ZA801441B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE9329T1 (de) * 1980-06-18 1984-09-15 May & Baker Limited Indol- und indolin-derivate.
US4543360A (en) * 1981-09-10 1985-09-24 Degussa Aktiengesellschaft 2-(Hydroxy-phenyl)-indoles and process for their production
DE3232968A1 (de) * 1981-09-10 1983-06-09 Degussa Ag, 6000 Frankfurt Neue 2-(hydroxy-phenyl)-indole und verfahren zu deren herstellung
GB2111050B (en) * 1981-11-19 1985-09-11 Ciba Geigy Ag N-substituted-2-pyridylindoles
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
KR20000057137A (ko) 1996-11-19 2000-09-15 스티븐 엠. 오드레 아릴 및 헤테로아릴로 치환된 융합 피롤 항염증제
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
NZ553329A (en) 2004-07-22 2010-09-30 Ptc Therapeutics Inc Thienopyridines for treating hepatitis C
DE102006053064A1 (de) * 2006-11-08 2008-05-21 Universität Potsdam Verfahren zur Herstellung aromatischer Diazoniumsalze

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin

Also Published As

Publication number Publication date
DD149804A5 (de) 1981-07-29
SU1028247A3 (ru) 1983-07-07
AU5636880A (en) 1980-09-18
US4343811A (en) 1982-08-10
GR75241B (xx) 1984-07-13
PT70921B (de) 1981-06-24
PT70921A (de) 1980-04-01
IL59598A0 (en) 1980-06-30
ES8101047A1 (es) 1980-12-01
NZ193111A (en) 1983-04-12
EP0015523B1 (de) 1982-10-13
CS208800B2 (en) 1981-09-15
FI800770A (fi) 1980-09-14
DE3060932D1 (en) 1982-11-18
ES490380A0 (es) 1980-12-01
DE2909779A1 (de) 1980-09-18
YU68180A (en) 1983-04-30
ATE1642T1 (de) 1982-10-15
ES488446A1 (es) 1980-10-01
CA1142519A (en) 1983-03-08
HU180126B (en) 1983-02-28
ES8101048A1 (es) 1980-12-01
ES490379A0 (es) 1980-12-01
NO800709L (no) 1980-09-15
EP0015523A1 (de) 1980-09-17
JPS55124758A (en) 1980-09-26
PL222634A1 (xx) 1980-12-01

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