ZA801441B - Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof - Google Patents

Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof

Info

Publication number
ZA801441B
ZA801441B ZA00801441A ZA801441A ZA801441B ZA 801441 B ZA801441 B ZA 801441B ZA 00801441 A ZA00801441 A ZA 00801441A ZA 801441 A ZA801441 A ZA 801441A ZA 801441 B ZA801441 B ZA 801441B
Authority
ZA
South Africa
Prior art keywords
indole derivatives
processes
preparation
pharmaceutical preparations
compounds
Prior art date
Application number
ZA00801441A
Other languages
English (en)
Inventor
G Griss
R Sauter
J Kaehling
W Grell
B Eisele
N Kaubisch
R Hurnaus
E Rupprecht
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA801441B publication Critical patent/ZA801441B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Power Steering Mechanism (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00801441A 1979-03-13 1980-03-12 Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof ZA801441B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792909779 DE2909779A1 (de) 1979-03-13 1979-03-13 Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA801441B true ZA801441B (en) 1981-11-25

Family

ID=6065240

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00801441A ZA801441B (en) 1979-03-13 1980-03-12 Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof

Country Status (21)

Country Link
US (1) US4343811A (xx)
EP (1) EP0015523B1 (xx)
JP (1) JPS55124758A (xx)
AT (1) ATE1642T1 (xx)
AU (1) AU5636880A (xx)
CA (1) CA1142519A (xx)
CS (1) CS208800B2 (xx)
DD (1) DD149804A5 (xx)
DE (2) DE2909779A1 (xx)
ES (3) ES488446A1 (xx)
FI (1) FI800770A (xx)
GR (1) GR75241B (xx)
HU (1) HU180126B (xx)
IL (1) IL59598A0 (xx)
NO (1) NO800709L (xx)
NZ (1) NZ193111A (xx)
PL (1) PL222634A1 (xx)
PT (1) PT70921B (xx)
SU (1) SU1028247A3 (xx)
YU (1) YU68180A (xx)
ZA (1) ZA801441B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA814057B (en) * 1980-06-18 1982-07-28 May & Baker Ltd Indole and indoline derivatives
DE3232968A1 (de) * 1981-09-10 1983-06-09 Degussa Ag, 6000 Frankfurt Neue 2-(hydroxy-phenyl)-indole und verfahren zu deren herstellung
US4543360A (en) * 1981-09-10 1985-09-24 Degussa Aktiengesellschaft 2-(Hydroxy-phenyl)-indoles and process for their production
GB2111050B (en) * 1981-11-19 1985-09-11 Ciba Geigy Ag N-substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
DE69728688T2 (de) 1996-11-19 2004-08-19 Amgen Inc., Thousand Oaks Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
MX2007000762A (es) 2004-07-22 2007-04-02 Ptc Therapeutics Inc Tienopiridinas para tratamientode hepatitis c.
DE102006053064A1 (de) * 2006-11-08 2008-05-21 Universität Potsdam Verfahren zur Herstellung aromatischer Diazoniumsalze

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use

Also Published As

Publication number Publication date
PT70921B (de) 1981-06-24
ATE1642T1 (de) 1982-10-15
ES8101048A1 (es) 1980-12-01
CS208800B2 (en) 1981-09-15
ES488446A1 (es) 1980-10-01
ES490379A0 (es) 1980-12-01
SU1028247A3 (ru) 1983-07-07
HU180126B (en) 1983-02-28
YU68180A (en) 1983-04-30
IL59598A0 (en) 1980-06-30
DD149804A5 (de) 1981-07-29
EP0015523B1 (de) 1982-10-13
JPS55124758A (en) 1980-09-26
EP0015523A1 (de) 1980-09-17
PT70921A (de) 1980-04-01
DE2909779A1 (de) 1980-09-18
PL222634A1 (xx) 1980-12-01
AU5636880A (en) 1980-09-18
NZ193111A (en) 1983-04-12
FI800770A (fi) 1980-09-14
GR75241B (xx) 1984-07-13
ES8101047A1 (es) 1980-12-01
NO800709L (no) 1980-09-15
CA1142519A (en) 1983-03-08
US4343811A (en) 1982-08-10
DE3060932D1 (en) 1982-11-18
ES490380A0 (es) 1980-12-01

Similar Documents

Publication Publication Date Title
ZA801441B (en) Indole derivatives,processes for the preparation,and pharmaceutical preparations thereof
AU582235B2 (en) Quinolylglycinamide derivatives,the process for preparation thereof and their therapeutic application as psychotropic drugs
NZ208691A (en) Dihydrodibenzocycloheptylidene-ethylpiperazine derivatives and pharmaceutical compositions thereof
ES476106A1 (es) Procedimiento para la preparacion de 4-espectinomicilamina.
PL288409A1 (en) Method of obtaining novel derivatives of 4-phenyl-4-piperidinecarboxyamide
DE3064183D1 (en) 4-aryloxy- and 4-arylthio-3-phenylpiperidine derivatives, a process for the preparation of such compounds and pharmaceutical compositions containing them
DE3366558D1 (en) Novel derivative of thienopyridinone, its preparation and its therapeutic use
DE3461378D1 (en) Rifamycins derivatives and preparation and pharmaceutical compositions thereof
ES8100015A1 (es) Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina.
DE3261606D1 (en) Novel quinolinecarboxylic acid derivative, process for production thereof, and antibacterial agent containing said compound as active ingredient
IL71068A0 (en) N-arylpiperazine derivative,its preparation and pharmaceutical compositions containing it
HUT40110A (en) Process for preparing indole derivatives
DE3262166D1 (en) A new p-chlorophenoxyacetic acid derivative, its method of preparation and pharmaceutical composition
JPS5681583A (en) Nbbquaternary 100bromsandwicinn and 100bromisosandwicin derivative* their manufacture* ringgopen aldehyde base and hearttbeat periodic trouble remedy
IL61224A (en) 10-bromosandwicine and 10-bromoisosandwicine,their preparation and pharmaceutical compositions containing them
GR79114B (xx)
DE3469527D1 (en) Nortropine derivative, process for its preparation and its use
PT81066A (en) Arphamine derivatives a process for their preparation and the pharmaceutical compositions therewith
ES483304A1 (es) Un procedimiento para la preparacion de derivados de benzo- diacepina