ES476106A1 - Procedimiento para la preparacion de 4-espectinomicilamina. - Google Patents
Procedimiento para la preparacion de 4-espectinomicilamina.Info
- Publication number
- ES476106A1 ES476106A1 ES476106A ES476106A ES476106A1 ES 476106 A1 ES476106 A1 ES 476106A1 ES 476106 A ES476106 A ES 476106A ES 476106 A ES476106 A ES 476106A ES 476106 A1 ES476106 A1 ES 476106A1
- Authority
- ES
- Spain
- Prior art keywords
- spectinomycylamin
- substances
- preparation
- acceptable salts
- physiologically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedimiento para la preparación de 4-espectinomicilamina de la fórmula y de sus sales por adición de ácido con ácidos inorgánicos u orgánicos, que se caracteriza porque a) se hodrogena un derivado espectinomicínico de la fórmula general donde X significa un átomo de hidrógeno, un grupo orgánico, conocido a partir de la química de los péptidos, fácilmente separable mediante reducción, tal como el grupo benciloxicarbonilo, el grupò 4-bromo- ó 4-nitro-ó 4-cloro- benciloxicarbonilo, el grupo 4-metoxi ó 3,4,- dimetoxi- ¿3,4-metilen-dihidroxi- ó 3,4,5- trimetoxi- ó deciloxi ó 4- acetoxi- ó etoxi-carboniloxibenciloxicarbonilo *** ver imagen 01 *** ver imagen 02 *** ver imagen 03
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772756914 DE2756914A1 (de) | 1977-12-21 | 1977-12-21 | 4-spectinomycylamin und seine physiologisch vertraegliche salze, verfahren zur herstellung und diese stoffe enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES476106A1 true ES476106A1 (es) | 1979-04-16 |
Family
ID=6026673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES476106A Expired ES476106A1 (es) | 1977-12-21 | 1978-12-19 | Procedimiento para la preparacion de 4-espectinomicilamina. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4173647A (es) |
| EP (1) | EP0002680B1 (es) |
| JP (1) | JPS5488299A (es) |
| AT (1) | AT362064B (es) |
| AU (1) | AU523036B2 (es) |
| CA (1) | CA1112649A (es) |
| DE (2) | DE2756914A1 (es) |
| DK (1) | DK572578A (es) |
| ES (1) | ES476106A1 (es) |
| FI (1) | FI783900A (es) |
| GR (1) | GR65649B (es) |
| HU (1) | HU178126B (es) |
| IL (1) | IL56248A (es) |
| NO (1) | NO784299L (es) |
| NZ (1) | NZ189246A (es) |
| PH (1) | PH13871A (es) |
| PT (1) | PT68939A (es) |
| ZA (1) | ZA787236B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282152A (en) * | 1979-08-23 | 1981-08-04 | The Upjohn Company | Intermediates for preparing spectinomycin and analogs thereof |
| US4337347A (en) * | 1979-08-23 | 1982-06-29 | The Upjohn Company | Process for preparing analogs of spectinomycin |
| US4345086A (en) * | 1979-08-23 | 1982-08-17 | The Upjohn Company | Intermediate compounds in the preparation of spectinomycin |
| US4344882A (en) * | 1979-08-23 | 1982-08-17 | The Upjohn Company | Intermediate compounds in the preparation of spectinomycin |
| US4465848A (en) * | 1981-10-23 | 1984-08-14 | The Upjohn Company | Spectinomycin compounds |
| US4532336A (en) * | 1982-03-19 | 1985-07-30 | The Upjohn Company | 6'-Alkylspectinomycins |
| JPS5945890A (ja) * | 1982-09-09 | 1984-03-14 | Toyo Jozo Co Ltd | 新規抗生物質アクミマイシンおよびその製造法 |
| US4523022A (en) * | 1983-07-07 | 1985-06-11 | The Upjohn Company | Analogs of the antibiotic spectinomycin |
| US4603212A (en) * | 1983-10-18 | 1986-07-29 | The Upjohn Company | Analogs of the antibiotic spectinomycin |
| US4578485A (en) * | 1984-02-08 | 1986-03-25 | The Upjohn Company | Synthesis of spectinomycin analogs by an improved Grignard process |
| DE3500005A1 (de) * | 1985-01-02 | 1986-07-10 | ESB Elektrostatische Sprüh- und Beschichtungsanlagen G.F. Vöhringer GmbH, 7758 Meersburg | Beschichtungskabine zum ueberziehen der oberflaeche von werkstuecken mit beschichtungspulver |
| WO1986005686A2 (en) * | 1985-03-29 | 1986-10-09 | The Upjohn Company | Treating chlamydia infections using spectinomycin analogs |
| AU2010275375B2 (en) * | 2009-07-24 | 2016-01-21 | University Of Tennessee Research Foundation | Spectinamides as anti-tuberculosis agents |
| JP6545177B2 (ja) * | 2013-09-29 | 2019-07-17 | セント ジュード チルドレンズ リサーチ ホスピタル インコーポレイテッド | 抗菌薬としてのアリール置換アミノメチルスペクチノマイシン類似体 |
| JP6923290B2 (ja) * | 2015-11-18 | 2021-08-18 | グローリー株式会社 | 貨幣処理装置および貨幣処理方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3165533A (en) * | 1962-01-22 | 1965-01-12 | Upjohn Co | Dihydroactinospectacin, amides and esters thereof |
| US3147277A (en) * | 1962-02-09 | 1964-09-01 | Upjohn Co | Nu, nu'-bis (alpha-sulfoalkyl) actinospectacins and process for their production |
-
1977
- 1977-12-21 DE DE19772756914 patent/DE2756914A1/de not_active Withdrawn
-
1978
- 1978-12-04 DE DE7878101542T patent/DE2860490D1/de not_active Expired
- 1978-12-04 AT AT863178A patent/AT362064B/de not_active IP Right Cessation
- 1978-12-04 EP EP78101542A patent/EP0002680B1/de not_active Expired
- 1978-12-04 US US05/965,869 patent/US4173647A/en not_active Expired - Lifetime
- 1978-12-12 JP JP15361278A patent/JPS5488299A/ja active Pending
- 1978-12-14 GR GR57882A patent/GR65649B/el unknown
- 1978-12-15 PH PH21950A patent/PH13871A/en unknown
- 1978-12-19 FI FI783900A patent/FI783900A/fi unknown
- 1978-12-19 ES ES476106A patent/ES476106A1/es not_active Expired
- 1978-12-19 PT PT68939A patent/PT68939A/pt unknown
- 1978-12-19 IL IL56248A patent/IL56248A/xx unknown
- 1978-12-20 NO NO784299A patent/NO784299L/no unknown
- 1978-12-20 DK DK572578A patent/DK572578A/da not_active Application Discontinuation
- 1978-12-20 AU AU42754/78A patent/AU523036B2/en not_active Expired
- 1978-12-20 NZ NZ189246A patent/NZ189246A/xx unknown
- 1978-12-20 CA CA318,320A patent/CA1112649A/en not_active Expired
- 1978-12-20 HU HU78TO1092A patent/HU178126B/hu unknown
- 1978-12-21 ZA ZA787236A patent/ZA787236B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI783900A (fi) | 1979-06-22 |
| HU178126B (en) | 1982-03-28 |
| DK572578A (da) | 1979-06-22 |
| DE2756914A1 (de) | 1979-07-05 |
| IL56248A0 (en) | 1979-03-12 |
| CA1112649A (en) | 1981-11-17 |
| AT362064B (de) | 1981-04-27 |
| AU523036B2 (en) | 1982-07-08 |
| PH13871A (en) | 1980-10-24 |
| EP0002680A2 (de) | 1979-07-11 |
| EP0002680A3 (en) | 1979-07-25 |
| NO784299L (no) | 1979-06-22 |
| ZA787236B (en) | 1980-08-27 |
| JPS5488299A (en) | 1979-07-13 |
| US4173647A (en) | 1979-11-06 |
| AU4275478A (en) | 1979-06-28 |
| EP0002680B1 (de) | 1981-02-11 |
| PT68939A (de) | 1979-01-01 |
| DE2860490D1 (en) | 1981-03-26 |
| GR65649B (en) | 1980-10-15 |
| IL56248A (en) | 1982-08-31 |
| NZ189246A (en) | 1981-03-16 |
| ATA863178A (de) | 1980-09-15 |
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